CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

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Browsing Family of Functional Category "Approved Drug"


IDNameSeedsMembers
CFFAD1 D(2) dopamine receptor ligand dibenzothiazepinone derivative Q... 2 7
CFFAD2 cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor xant... 18 210
CFFAD3 D(2) dopamine receptor ligand Benzisoxazole Derivative Risperi... 3 32
CFFAD4 Abelson tyrosine-protein kinase 2 inhibitor thiazole derivativ... 19 50
CFFAD5 Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
CFFAD6 Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
CFFAD7 Glucocorticoid receptor ligand glucocorticoid analog Dexameth... 13 248
CFFAD8 5-hydroxytryptamine receptor 1B ligand triptan Almotriptan Family 8 438
CFFAD9 Retinoic acid receptor ligand retinoid Isotretinoin Family 9 29
CFFAD10 5-hydroxytryptamine receptor 2C ligand Tetracyclic antidepress... 14 498
CFFAD11 Enoyl-[acyl-carrier-protein] reductase [NADH] inhibitor pyridi... 3 24
CFFAD12 Aldehyde dehydrogenase inhibitor thiocarbonyl compound Disulfi... 1 0
CFFAD13 Adenosine deaminase inhibitor pyrimido-pyrimidine derivative D... 6 25
CFFAD14 Calcineurin Inhibitor Cyclosporine Family 15 52
CFFAD15 NMDA receptor Ligand L-glutamic Acid Family 6 32
CFFAD16 D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
CFFAD17 Opioid receptor ligand synthetic opioid methadone analog Dextr... 2 108
CFFAD18 Vasopressin V2 receptor ligand peptide analog Desmopressin family 111 1472
CFFAD19 D(2) dopamine receptor and D(3) dopamine receptor ligand amino... 2 6
CFFAD20 Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
CFFAD21 Benzodiazepine receptor ligand benzodiazepine derivative Fludi... 11 78
CFFAD22 D(2) dopamine receptor ligand thienobenzodiazepine analog Olan... 3 2
CFFAD23 Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
CFFAD24 Beta adrenergic receptor ligand monosubstituted indole derivat... 14 475
CFFAD25 D(2) dopamine receptor ligand thioxanthene analog Flupenthixol... 2 3
CFFAD26 Nicotinic acetylcholine receptor ligand secondary aliphatic am... 3 0
CFFAD27 D(2) dopamine receptor ligand dibenzodiazepine derivative Cloz... 2 1
CFFAD28 Endothelin B receptor and Endothelin-1 receptor ligand pyrimid... 22 180
CFFAD29 5-hydroxytryptamine receptor 1A ligand azapirone derivative Bu... 4 20
CFFAD30 30S ribosomal subunit Inhibitor Tetracycline Family 6 1
CFFAD31 Oestrogen receptor Ligand Mitotane Family 1 25
CFFAD32 Calmodulin inhibitor phenothiazine derivative Trifluoperazine ... 3 30
CFFAD33 Solute carrier family 12 member 1 inhibitor hydrochlorothiazid... 4 4
CFFAD34 30S ribosomal subunit inhibitor aminoglycoside Neomycin Family 10 11
CFFAD35 G protein-activated inward rectifier potassium channel 4 ligan... 6 9
CFFAD36 Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
CFFAD37 Voltage-gated sodium channel ligand phenyltriazine analog Lamo... 2 4
CFFAD38 Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
CFFAD39 DNA binder bis-chloroethylnitrosourea analog Carmustine family 1 1
CFFAD40 5-hydroxytryptamine receptor 2C ligand phenylpiperazine analog... 1 4
CFFAD41 Solute carrier family 12 member 1 inhibitor aminobenzenesulfon... 1 0
CFFAD42 5-alpha reductase inhibitor azasteroid derivative Dutasteride ... 36 124
CFFAD43 5-alpha reductase inhibitor azasteroid derivative Finasteride ... 3 30
CFFAD44 DNA topoisomerase 2-beta inhibitor acridine derivative Amsacri... 1 4
CFFAD45 Beta adrenergic receptor Ligand Bethanidine Family 2 22
CFFAD46 Tumor necrosis factor inhibitor xanthine derivative Pentoxifyl... 5 69
CFFAD47 Thymidylate synthase inhibitor pyrrotopyrimidine derivative Pe... 4 23
CFFAD48 DNA binder anthracycline analog Doxorubicin family 9 32
CFFAD49 Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118
CFFAD50 Noradrenergic re-uptake and Serotonin re-uptake inhibitor phen... 18 41
CFFAD51 Lipase inhibitor lipstatin derivative Orlistat family 1 9
CFFAD52 Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
CFFAD53 Probable arabinosyltransferase Inhibitor Ethambutol Family 1 5
CFFAD54 HIV reverse transcriptase inhibitor phosphonate derivative Fos... 2 0
CFFAD55 DNA binder anthracycline analog Mitoxantrone family 2 15
CFFAD56 Alpha adrenergic receptor ligand dioxolane analog guanadrel fa... 1 0
CFFAD57 Reverse transcriptase inhibitor nucleotide adenosine monophosp... 4 24
CFFAD58 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Methyl... 9 7
CFFAD59 DNA binder platinum-based diaminocyclohexane analog Oxaliplati... 1 0
CFFAD60 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
CFFAD61 Alpha-2 adrenergic receptor ligand Clonidine derivative Lofexi... 2 2
CFFAD62 Beta adrenergic receptor ligand quinolone derivative Carteolol... 1 38
CFFAD63 Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
CFFAD64 D(2) dopamine receptor and D(3) dopamine receptor ligand indol... 4 123
CFFAD65 D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
CFFAD66 Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
CFFAD67 Delta-type opioid receptor ligand opiate analog Codeine Family 15 184
CFFAD68 Mu-type opioid receptor Ligand Fentanyl Family 9 647
CFFAD69 u-type opioid receptor ligand opiate analog Buprenorphine Family 78 234
CFFAD70 Muscarinic acetylcholine receptor M3 ligand quinuclidine deriv... 1 0
CFFAD71 D(2) dopamine receptor ligand phenylpiperazine derivative Arip... 3 53
CFFAD72 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 4 171
CFFAD73 Alpha adrenergic receptor ligand ergot alkaloid Dihydroergota... 7 12
CFFAD74 D(2) dopamine receptor ligand benzothiazolylpiperazine derivat... 6 56
CFFAD75 Alpha-1B adrenergic receptor ligand phenethylamine derivative ... 12 283
CFFAD76 Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
CFFAD77 Benzodiazepine receptor ligand benzodiazepine analog Chlordiaz... 1 0
CFFAD78 Aldosterone receptor ligand steroid Eplerenone family 2 3
CFFAD79 Alpha-1 adrenergic receptor ligand sulfamoyl substituted phene... 4 13
CFFAD80 Alpha-2 adrenergic receptor Ligand Yohimbine Family 7 52
CFFAD81 Beta adrenergic receptor Ligand Timolol Family 1 3
CFFAD82 Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
CFFAD83 Progesterone receptor ligand steroid Mifepristone family 14 75
CFFAD84 Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
CFFAD85 Androgen receptor Ligand Bicalutamide Family 3 21
CFFAD86 NMDA receptor Ligand dicarbamate derivative Felbamate Family 1 4
CFFAD87 Gonadotropin-releasing hormone receptor Ligand decapeptide ana... 9 162
CFFAD88 u-type opioid receptor ligand opiate opiate analog Oxymorphone... 22 105
CFFAD89 Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
CFFAD90 xanthine alkaloid Theobromine family 6 10
CFFAD91 D(2) dopamine receptor Ligand phenothiazine analog Prochlorper... 4 25
CFFAD92 Histamine H1 receptor ligand tricyclic antidepressant Loratadi... 5 163
CFFAD93 Histamine H1 receptor Ligand Terfenadine Family 3 50
CFFAD94 5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680
CFFAD95 Noradrenergic re-uptake and Serotonin re-uptake Inhibitor phen... 1 6
CFFAD96 Nicotinic acetylcholine receptor alpha subunit Ligand benzylis... 4 18
CFFAD97 Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
CFFAD98 50S ribosomal subunit Inhibitor macrolide ketolide antibiotics... 1 0
CFFAD99 50S ribosomal subunit inhibitor macrolide antibiotics Erythrom... 5 45
CFFAD100 Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
CFFAD101 Tubulin beta-2 chain inhibitor indole alkaloid Vinblastine Fa... 5 24
CFFAD102 Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
CFFAD103 Aminoglycoside antibiotics Micronomicin family 4 0
CFFAD104 Peptidoglycan synthase FtsI Inhibitor beta-lactam monobactam a... 2 22
CFFAD105 Serotonin re-uptake Inhibitor Citalopram Family 6 4
CFFAD106 Sodium/potassium-transporting ATPase Inhibitor Cardiac glycosi... 19 97
CFFAD107 Sodium channel Ligand xylidine derivative Mepivacaine Family 10 114
CFFAD108 Nicotinic acetylcholine receptor ligand aminosteroid Pancuroni... 3 5
CFFAD109 Adrenergic neuron Inhibitor guanidine azocine analog Guanethid... 1 0
CFFAD110 Adrenergic neuron Inhibitor guanidine isoquinoline analog Debr... 2 44
CFFAD111 Potassium voltage-gated channel subfamily D member 3 and Volta... 2 2
CFFAD112 Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
CFFAD113 Sodium channel Ligand hydantoin derivative Phenytoin Family 2 25
CFFAD114 Sodium/potassium-transporting ATPase subunit alpha-1 Inhibitor... 1 10
CFFAD115 SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand s... 1 2
CFFAD116 SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand R... 1 16
CFFAD117 Voltage-dependent calcium channel gamma-1 subunit Ligand Israd... 3 2
CFFAD118 SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand T... 3 35
CFFAD119 Glutamate receptor ionotropic, kainate 1 Ligand Topiramate Family 2 10
CFFAD120 Cytochrome P450 3A4 Inhibitor Clotrimazole Family 16 145
CFFAD121 Calcium channel Ligand Felodipine Family 4 25
CFFAD122 Alpha-1 adrenergic receptor ligand ergot alkaloid Ergotamine F... 1 0
CFFAD123 Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
CFFAD124 ATP-sensitive inward rectifier potassium channel 10 Ligand Min... 1 0
CFFAD125 30S ribosomal subunit inhibitor aminoglycoside Streptomycin Fa... 1 1
CFFAD126 Penicillin binding protein inhibitor cephalosporin Cefpodoxime... 8 90
CFFAD127 Inosine-5'-monophosphate dehydrogenase Inhibitor Mercaptopurin... 2 3
CFFAD128 3-beta-hydroxysteroid dehydrogenase Inhibitor Trilostane Family 2 0
CFFAD129 Acetylcholinesterase Inhibitor Rivastigmine Family 2 59
CFFAD130 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Amrino... 3 55
CFFAD131 Prostaglandin G/H synthase 2 Inhibitor Diflunisal Family 7 421
CFFAD132 5-aminoimidazole-4-carboxamidoribonucleotide (AICAR) transform... 1 0
CFFAD133 14-alpha sterol demethylase inhibitor imidazole derivative Mi... 6 59
CFFAD134 D-alanyl-D-alanine carboxypeptidase Inhibitor Cefalotin Family 2 13
CFFAD135 Dihydroorotate dehydrogenase Inhibitor Atovaquone Family 1 4
CFFAD136 Epidermal Growth Factor family 111 209
CFFAD137 DNA topoisomerase 2-beta Inhibitor Gatifloxacin Family 9 52
CFFAD138 DNA topoisomerase 2-beta and DNA topoisomerase 2-beta inhibito... 9 181
CFFAD139 Serine/threonine-protein kinase mTOR and Serine/threonine-prot... 14 34
CFFAD140 Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0
CFFAD141 Gamma-aminobutyric acid uptake Inhibitor Tiagabine Family 1 16
CFFAD142 Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
CFFAD143 Glycogen synthase kinase-3 Inhibitor Lithium Family 1 1
CFFAD144 DNA polymerase/reverse transcriptase and Reverse transcriptase... 3 5
CFFAD145 HIV protease Inhibitor Indinavir Family 36 211
CFFAD146 HIV protease Inhibitor Ritonavir Family 12 49
CFFAD147 HIV protease Inhibitor Amprenavir Family 7 15
CFFAD148 HIV protease Inhibitor Saquinavir Family 64 428
CFFAD149 HIV reverse transcriptase Inhibitor Stavudine Family 1 5
CFFAD150 Inosine-5'-monophosphate dehydrogenase Inhibitor Ribavirin Family 3 3
CFFAD151 Maltase-glucoamylase, intestinal Inhibitor Acarbose Family 2 2
CFFAD152 Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
CFFAD153 Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Sibu... 7 127
CFFAD154 Histamine H1 receptor Ligand Doxepin Family 8 89
CFFAD155 P2Y purinoceptor 12 Inhibitor Clopidogrel Family 2 3
CFFAD156 Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
CFFAD157 Potassium-transporting ATPase alpha chain 1 Inhibitor Rabepraz... 4 113
CFFAD158 Prostaglandin G/H synthase 2 inhibitor Oxicam derivative Pirox... 1 0
CFFAD159 Farnesyl pyrophosphate synthase (Fragment) and Receptor-type t... 1 2
CFFAD160 Reverse transcriptase Inhibitor Delavirdine Family 1 68
CFFAD161 Reverse transcriptase Inhibitor Nevirapine Family 23 640
CFFAD162 Trypsin inhibitor polypeptide Aprotinin Family 7 68
CFFAD163 Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
CFFAD164 Amiloride-sensitive sodium channel subunit alpha Ligand Amilor... 3 10
CFFAD165 Solute carrier family 12 member 1 and Solute carrier family 12... 2 2
CFFAD166 Antithrombin-III Inhibitor Heparin Family 2 74
CFFAD167 cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Cilo... 1 8
CFFAD168 Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
CFFAD169 Nicotinic acetylcholine receptor Ligand Cisatracurium Besylate... 1 0
CFFAD170 RNA polymerase inhibitor rifamycin derivative Rifampin Family 3 1
CFFAD171 Peptidyl-prolyl cis-trans isomerase A and Peptidyl-prolyl cis-... 2 35
CFFAD172 Plasminogen Inhibitor Tranexamic Acid Family 4 14
CFFAD173 Plasminogen Inhibitor Aminocaproic Acid Family 4 37
CFFAD174 NMDA receptor Ligand Magnesium Family 2 0
CFFAD175 Acetyl-CoA carboxylase 2 Inhibitor Metformin Family 1 0
CFFAD176 AMP-activated protein kinase Inhibitor Phenformin Family 5 14
CFFAD177 Cannabinoid receptor 1 Ligand Marinol Family 32 454
CFFAD178 Chloride channel protein 2 Ligand Lubiprostone Family 1 1
CFFAD179 Dopamine receptor ligand L-Tyrosine derivative Levodopa Family 4 59
CFFAD180 Lipoprotein lipase Inhibitor Gemfibrozil Family 1 28
CFFAD181 Vitamin D3 receptor ligand Vitamin D analog Calcitriol Family 49 120
CFFAD182 Opioid receptor ligand opiate Levorphanol Family 18 537
CFFAD183 DNA Binder Cisplatin Family 1 1
CFFAD184 DNA Binder Primaquine Family 3 245
CFFAD185 Vasopressin V1a receptor Ligand Felypressin Family 12 820
CFFAD186 5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family 7 460
CFFAD187 5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
CFFAD188 D(2) dopamine receptor Ligand Nemonapride Family 70 283
CFFAD189 Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
CFFAD190 Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
CFFAD191 Alpha adrenergic receptor ligand L-Tyrosine derivative Methyld... 2 3
CFFAD192 D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
CFFAD193 Alpha-1 adrenergic receptor ligand Dextroamphetamine derivativ... 5 29
CFFAD194 Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
CFFAD195 Alpha-2 adrenergic receptor Ligand Clonidine Family 4 20
CFFAD196 Alpha-2 adrenergic receptor Ligand Guanabenz Family 2 9
CFFAD197 Alpha-2 adrenergic receptor Ligand Dexmedetomidine Family 32 639
CFFAD198 Alpha-2 adrenergic receptor Ligand Tizanidine Family 1 1
CFFAD199 Alpha-2 adrenergic receptor Ligand Oxymetazoline Family 5 4
CFFAD200 Benzodiazepine receptor ligand benzodiazepine derivative Oxaze... 4 0
CFFAD201 Benzodiazepine receptor Ligand Alprazolam Family 4 35
CFFAD202 Benzodiazepine receptor Ligand Clorazepate Family 2 3
CFFAD203 Benzodiazepine receptor Ligand Midazolam Family 5 160
CFFAD204 Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
CFFAD205 Beta-2 adrenergic receptor Ligand Formoterol Family 16 63
CFFAD206 Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
CFFAD207 Beta-2 adrenergic receptor Ligand Pirbuterol Family 1 1
CFFAD208 Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
CFFAD209 D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
CFFAD210 Alpha adrenergic receptor ligand phenothiazine derivative Thio... 4 10
CFFAD211 D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
CFFAD212 Extracellular calcium-sensing receptor ligand Cinacalcet Family 2 30
CFFAD213 Gamma-aminobutyric acid B receptor Ligand Baclofen Family 5 12
CFFAD214 Gamma-aminobutyric acid B receptor Ligand Progabide Family 1 3
CFFAD215 Gamma-aminobutyric acid receptor ligand benzodiazepine derivat... 2 8
CFFAD216 Gastrin/cholecystokinin type B receptor ligand peptide Pentaga... 26 1171
CFFAD217 Glutamate-gated chloride channel Ligand Ivermectin Family 3 18
CFFAD218 Lipoprotein lipase Inhibitor Clofibrate Family 3 28
CFFAD219 Muscarinic acetylcholine receptor Ligand Bethanechol Family 3 2
CFFAD220 Mu-type opioid receptor ligand opiate Remifentanil Family 10 24
CFFAD221 Neuronal acetylcholine receptor subunit alpha-4 Ligand Varenic... 3 54
CFFAD222 Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
CFFAD223 Opioid receptor Ligand Methadone Family 3 39
CFFAD224 Oxytocin receptor Ligand Oxytocin Family 30 182
CFFAD225 Peroxisome proliferator-activated receptor alpha Ligand Fenofi... 3 127
CFFAD226 Peroxisome proliferator-activated receptor gamma Ligand Piogli... 2 29
CFFAD227 Prostaglandin E2 receptor EP2 subtype Ligand Iloprost Family 2 37
CFFAD228 Prostaglandin F2-alpha receptor ligand prostaglandin analog Tr... 4 35
CFFAD229 Retinoid X receptor Ligand Bexarotene Family 7 492
CFFAD230 Sigma non-opioid intracellular receptor 1 ligand opiate Dextro... 9 33
CFFAD231 Toll-like receptor 7 Ligand Imiquimod Family 3 237
CFFAD232 Voltage-dependent L-type calcium channel subunit alpha-1C Liga... 2 12
CFFAD233 Alpha-2A adrenergic receptor Ligand Brimonidine Family 3 6
CFFAD234 D(1B) dopamine receptor Ligand Apomorphine Family 30 271
CFFAD235 D(2) dopamine receptor Ligand Bromocriptine Family 2 0
CFFAD236 Glutamate receptor ionotropic, NMDA 2A Ligand Glycine Family 1 1
CFFAD237 Vitamin D3 receptor ligand Vitamin D analog Cholecalciferol Fa... 7 270
CFFAD238 Noradrenergic re-uptake inhibitor Dibenzazepine Imipramine Family 8 178
CFFAD239 5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
CFFAD240 Sodium channel protein type 10 subunit alpha Ligand Tetracaine... 6 166
CFFAD241 Aldosterone receptor Ligand Spironolactone Family 1 21
CFFAD242 Alpha adrenergic receptor Ligand Dapiprazole Family 1 7
CFFAD243 Alpha adrenergic receptor Ligand Phentolamine Family 2 9
CFFAD244 Alpha-1D adrenergic receptor Ligand Terazosin Family 28 638
CFFAD245 Androgen receptor ligand aniline derivative Flutamide Family 3 9
CFFAD246 Androgen receptor ligand aniline derivative Nilutamide Family 1 1
CFFAD247 Beta adrenergic receptor Ligand Levobunolol Family 6 133
CFFAD248 Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
CFFAD249 Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
CFFAD250 Calcium channel ligand dihydropyridine derivative Nisoldipine ... 18 94
CFFAD251 Cannabinoid receptor 1 Ligand Rimonabant Family 20 260
CFFAD252 C-C chemokine receptor type 5 Ligand Maraviroc Family 29 81
CFFAD253 Cysteinyl leukotriene receptor 1 Ligand Montelukast Family 37 29
CFFAD254 D(2) dopamine receptor Ligand Sulpiride Family 7 38
CFFAD255 D(2) dopamine receptor Ligand Loxapine Family 5 6
CFFAD256 D(2) dopamine receptor Ligand Remoxipride Family 12 84
CFFAD257 D(2) dopamine receptor Ligand Haloperidol Family 5 53
CFFAD258 Delta-aminolevulinic acid dehydratase Inhibitor Aminolevulinic... 3 2
CFFAD259 D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
CFFAD260 Dopamine receptor Ligand Domperidone Family 2 21
CFFAD261 Dopamine receptor Ligand Thiothixene Family 2 1
CFFAD262 Oestrogen receptor ligand steroid Estradiol derivative Fulvest... 3 64
CFFAD263 Glucocorticoid receptor ligand glucocorticoid analog Flunisol... 10 41
CFFAD264 Heat shock protein 90, putative Inhibitor Amlexanox Family 1 2
CFFAD265 Histamine H1 receptor Ligand Clemastine Family 5 76
CFFAD266 Histamine H1 receptor Ligand Cetirizine Family 4 4
CFFAD267 Histamine H1 receptor Ligand Astemizole Family 7 240
CFFAD268 Histamine H1 receptor Ligand Propiomazine Family 4 10
CFFAD269 Histamine H1 receptor Ligand Ketotifen Family 2 8
CFFAD270 Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
CFFAD271 Histamine H1 receptor Ligand Azelastine Family 14 29
CFFAD272 Histamine H1 receptor Ligand Dimenhydrinate Family 1 0
CFFAD273 Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
CFFAD274 Histamine H1 receptor Ligand Levocabastine Family 1 1
CFFAD275 Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
CFFAD276 Histamine H2 receptor Ligand Cimetidine Family 2 14
CFFAD277 Histamine H2 receptor Ligand Nizatidine Family 1 3
CFFAD278 Histamine H2 receptor Ligand Ranitidine Family 1 6
CFFAD279 Histamine H2 receptor Ligand Famotidine Family 1 2
CFFAD280 Muscarinic acetylcholine receptor Ligand Flutropium Bromide Fa... 6 45
CFFAD281 Muscarinic acetylcholine receptor M2 ligand Tropane alkaloid S... 7 16
CFFAD282 Muscarinic acetylcholine receptor M3 Ligand Tiotropium Family 6 2
CFFAD283 Muscarinic acetylcholine receptor M4 Ligand Tropicamide Family 3 73
CFFAD284 Muscarinic acetylcholine receptor M5 Ligand Metixene Family 5 24
CFFAD285 Neuronal acetylcholine receptor subunit alpha-2 ligand aminost... 2 0
CFFAD286 Neuronal acetylcholine receptor subunit alpha-2 Ligand Metocur... 18 169
CFFAD287 Opioid receptor Ligand Sufentanil Family 4 13
CFFAD288 Prostaglandin E2 receptor EP2 subtype Ligand Alprostadil Family 11 127
CFFAD289 Solute carrier family 12 member 1 Inhibitor Bumetanide Family 2 11
CFFAD290 Substance-P receptor Ligand Aprepitant Family 4 8
CFFAD291 Type-1 angiotensin II receptor Ligand Valsartan Family 2 27
CFFAD292 Type-1 angiotensin II receptor Ligand Irbesartan Family 8 46
CFFAD293 5-hydroxytryptamine receptor 3A Ligand Palonosetron Family 12 403
CFFAD294 5-hydroxytryptamine receptor 3A Ligand Dolasetron Family 12 171
CFFAD295 Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
CFFAD296 Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
CFFAD297 Neuronal acetylcholine receptor subunit alpha-2 Ligand Decamet... 4 40
CFFAD298 Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
CFFAD299 Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
CFFAD300 23S rRNA Inhibitor Linezolid Family 1 19
CFFAD301 30S ribosomal subunit Inhibitor Amikacin Family 4 1
CFFAD302 30S ribosomal subunit Inhibitor Demeclocycline Family 3 2
CFFAD303 30S ribosomal subunit inhibitor aminoglycoside Spectinomycin F... 1 1
CFFAD304 30S ribosomal subunit inhibitor Aminoglycoside Netilmicin Family 2 2
CFFAD305 30S ribosomal subunit Inhibitor Minocycline Family 2 2
CFFAD306 50S ribosomal subunit inhibitor macrolide Azithromycin Family 2 5
CFFAD307 50S ribosomal subunit Inhibitor Clindamycin Family 2 6
CFFAD308 50S ribosomal subunit inhibitor macrolide Troleandomycin Family 1 2
CFFAD309 Alpha adrenergic receptor Ligand Droperidol Family 20 244
CFFAD310 Alpha-1B adrenergic receptor Ligand Propericiazine Family 2 0
CFFAD311 cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Vardena... 3 39
CFFAD312 Corticosteroid-binding globulin inhibitor corticosteroid analo... 6 10
CFFAD313 Corticosteroid-binding globulin Inhibitor Rimexolone Family 6 138
CFFAD314 Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
CFFAD315 Delta-type opioid receptor Ligand Loperamide Family 8 55
CFFAD316 Gamma-aminobutyric acid A receptor Ligand Zopiclone Family 2 1
CFFAD317 Melatonin receptor type 1A Ligand Melatonin Family 20 988
CFFAD318 Penicillin binding protein Inhibitor Ertapenem Family 1 0
CFFAD319 Penicillin binding protein inhibitor β-lactam aminopenicillin ... 12 359
CFFAD320 Penicillin binding protein Inhibitor Ceftazidime Family 1 27
CFFAD321 Penicillin binding protein inhibitor β-lactam carbacephem Lora... 1 5
CFFAD322 Penicillin binding protein Inhibitor Cloxacillin Family 4 6
CFFAD323 Penicillin binding protein inhibitor β-lactam cephalosporin Ce... 3 38
CFFAD324 Penicillin-binding protein 2B Inhibitor Imipenem Family 3 40
CFFAD325 Penicillin binding protein Inhibitor Cefadroxil Family 5 17
CFFAD326 Penicillin binding protein inhibitor cephalosporin Cefditoren ... 1 2
CFFAD327 Penicillin binding protein Inhibitor Cefuroxime Family 1 7
CFFAD328 Penicillin binding protein inhibitor β-lactam cephalosporin Ce... 2 15
CFFAD329 Penicillin binding protein Inhibitor Cefazolin Family 2 7
CFFAD330 Penicillin binding protein Inhibitor Cefpiramide Family 3 6
CFFAD331 Penicillin binding protein inhibitor β-lactam cephamycin Cefot... 2 2
CFFAD332 Penicillin binding protein Inhibitor Cefradine Family 2 3
CFFAD333 Penicillin binding protein inhibitor cephalosporin Ceftibuten ... 2 2
CFFAD334 Penicillin binding protein Inhibitor Ticarcillin Family 2 0
CFFAD335 Peptidyl tranferase Inhibitor Chloramphenicol Family 1 3
CFFAD336 Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
CFFAD337 Retinoic acid receptor gamma Ligand Tazarotene Family 1 0
CFFAD338 Serotonin re-uptake Inhibitor Paroxetine Family 6 19
CFFAD339 Sodium/potassium-transporting ATPase subunit alpha-1 Inhibitor... 2 2
CFFAD340 Sodium/potassium-transporting ATPase subunit alpha-1 Inhibitor... 1 1
CFFAD341 Sodium/potassium-transporting ATPase subunit alpha-1 Inhibitor... 3 15
CFFAD342 Thromboxane A2 receptor Ligand Ridogrel Family 7 83
CFFAD343 Tubulin beta chain Inhibitor Paclitaxel Family 7 19
CFFAD344 Tyrosine 3-monooxygenase Inhibitor L-tyrosine Family 4 36
CFFAD345 5-hydroxytryptamine receptor 2B Ligand Minaprine Family 2 42
CFFAD346 Alpha adrenergic receptor Ligand Tolazoline Family 7 51
CFFAD347 Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
CFFAD348 Beta adrenergic receptor Ligand Metipranolol Family 5 1
CFFAD349 Beta-1 adrenergic receptor Ligand Acebutolol Family 2 27
CFFAD350 Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
CFFAD351 Calcium channel ligand dihydropyridine derivative Nicardipine ... 10 16
CFFAD352 DNA polymerase inhibitor guanosine analog Aciclovir Family 4 41
CFFAD353 DNA polymerase catalytic subunit Inhibitor Famciclovir Family 1 6
CFFAD354 Histamine H1 receptor Ligand Diphenhydramine Family 5 75
CFFAD355 Calcium-activated potassium channel subunit alpha-1 Ligand Qui... 3 46
CFFAD356 NMDA receptor ligand Adamantane derivative Memantine Family 4 5
CFFAD357 Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Dulo... 8 6
CFFAD358 Potassium voltage-gated channel subfamily H member 2 Ligand Do... 5 30
CFFAD359 Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
CFFAD360 Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 1 0
CFFAD361 Ryanodine receptor 2 Ligand Dantrolene Family 1 0
CFFAD362 Sodium channel protein type 1 subunit alpha ligand sulfonamide... 1 4
CFFAD363 Sodium channel protein type 1 subunit alpha Ligand Phenacemide... 5 6
CFFAD364 Sodium channel protein type 1 subunit alpha Ligand Levetiracet... 7 56
CFFAD365 Sodium channel protein type 5 subunit alpha Ligand Indecainide... 2 41
CFFAD366 Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
CFFAD367 Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
CFFAD368 Sodium channel protein type 5 subunit alpha Ligand Hexylcaine ... 4 94
CFFAD369 Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
CFFAD370 Sodium channel protein type 5 subunit alpha Ligand Mephenytoin... 5 51
CFFAD371 Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
CFFAD372 Sodium channel protein type 5 subunit alpha Ligand Moricizine ... 1 0
CFFAD373 Sodium channel protein type 5 subunit alpha Ligand Proparacain... 2 26
CFFAD374 Sodium channel protein type 5 subunit alpha Ligand Procainamid... 7 291
CFFAD375 Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
CFFAD376 Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
CFFAD377 Solute carrier family 12 member 1 Inhibitor Chlorthalidone Family 1 0
CFFAD378 SUR1-type K(ATP) channel Ligand Gliclazide Family 2 0
CFFAD379 Type-1 angiotensin II receptor Ligand Losartan Family 3 90
CFFAD380 Type-1 angiotensin II receptor Ligand Candesartan Family 3 75
CFFAD381 Voltage-dependent L-type calcium channel Ligand Bepridil Family 2 2
CFFAD382 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 0
CFFAD383 Voltage-gated sodium channel Ligand Riluzole Family 1 17
CFFAD384 Voltage-gated sodium channel Ligand Oxcarbazepine Family 1 4
CFFAD385 DNA Binder Bleomycin Family 3 1
CFFAD386 DNA Binder Cyclophosphamide Family 2 3
CFFAD387 DNA Binder Dacarbazine Family 1 0
CFFAD388 DNA Binder Metronidazole Family 1 5
CFFAD389 DNA Binder Carboplatin Family 1 0
CFFAD390 DNA Binder Dactinomycin Family 2 6
CFFAD391 Tyrosine 3-monooxygenase Inhibitor Tetrahydrobiopterin Family 3 8
CFFAD392 Keratin Inhibitor Griseofulvin Family 1 11
CFFAD393 Insulin receptor Ligand Insulin, Porcine Family 61 205
CFFAD394 4-aminobutyrate aminotransferase, mitochondrial Inhibitor Pyru... 1 2
CFFAD395 Aldehyde oxidase inhibitor para-naphthoquinone Menadione Family 22 503
CFFAD396 Succinate-semialdehyde dehydrogenase, mitochondrial Inhibitor ... 1 4
CFFAD397 Glucan synthesis regulatory protein Inhibitor Anidulafungin Fa... 2 5
CFFAD398 Glucan synthesis regulatory protein Inhibitor Caspofungin Family 17 71
CFFAD399 Glucan synthesis regulatory protein Inhibitor Micafungin Family 1 1
CFFAD400 Steroid 17-alpha-hydroxylase/17,20 lyase Inhibitor Progesteron... 20 283
CFFAD401 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Lova... 13 79
CFFAD402 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Ator... 3 24
CFFAD403 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Fluv... 6 53
CFFAD404 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor Stat... 2 4
CFFAD405 4-aminobutyrate aminotransferase, mitochondrial Inhibitor Diva... 2 28
CFFAD406 4-aminobutyrate aminotransferase, mitochondrial Inhibitor Viga... 1 0
CFFAD407 Acetylcholinesterase Inhibitor Tacrine Family 12 515
CFFAD408 Acetylcholinesterase Inhibitor Galantamine Family 4 49
CFFAD409 Acetylcholinesterase Inhibitor Donepezil Family 23 242
CFFAD410 Acetylcholinesterase Inhibitor Physostigmine Family 13 155
CFFAD411 Acetylcholinesterase Inhibitor Edrophonium Family 7 40
CFFAD412 Acetylcholinesterase Inhibitor Neostigmine Family 4 76
CFFAD413 ADP/ATP translocase 1 Inhibitor Clodronate Family 1 0
CFFAD414 Adenosine deaminase Inhibitor Pentostatin Family 4 13
CFFAD415 Alcohol dehydrogenase [NADP(+)] Inhibitor Fomepizole Family 2 1
CFFAD416 Aldose reductase Inhibitor Sulindac Family 4 12
CFFAD417 Alkaline phosphatase, tissue-nonspecific isozyme Inhibitor Lev... 2 5
CFFAD418 Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
CFFAD419 Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
CFFAD420 Amiloride-sensitive sodium channel subunit alpha Ligand Triamt... 8 98
CFFAD421 Amine oxidase [flavin-containing] A Inhibitor Moclobemide Family 5 255
CFFAD422 Amine oxidase [flavin-containing] A inhibitor hydrazine antide... 1 1
CFFAD423 Amine oxidase [flavin-containing] B Inhibitor Phenelzine Family 7 15
CFFAD424 Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26
CFFAD425 Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 16 374
CFFAD426 Angiotensin-converting enzyme inhibitor Phosphonate-containing... 7 41
CFFAD427 Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
CFFAD428 Angiotensin-converting enzyme Inhibitor Moexipril Family 5 469
CFFAD429 Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
CFFAD430 Angiotensin-converting enzyme Inhibitor Captopril Family 13 27
CFFAD431 Arachidonate 5-lipoxygenase Inhibitor Zileuton Family 1 27
CFFAD432 Beta adrenergic receptor Ligand Dipivefrin Family 3 55
CFFAD433 Calcineurin inhibitor macrolactam Pimecrolimus Family 24 1
CFFAD434 cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor xant... 3 7
CFFAD435 Carbonic anhydrase Inhibitor Ethoxzolamide Family 2 42
CFFAD436 Carbonic anhydrase Inhibitor Methazolamide Family 1 3
CFFAD437 Carbonic anhydrase Inhibitor Acetazolamide Family 6 15
CFFAD438 Carbonic anhydrase Inhibitor Dichlorphenamide Family 1 2
CFFAD439 Carbonic anhydrase Inhibitor Brinzolamide Family 2 38
CFFAD440 Carbonic anhydrase 2 Inhibitor Benzthiazide Family 1 0
CFFAD441 Carbonic anhydrase 2 Inhibitor Cyclothiazide Family 1 0
CFFAD442 Carbonic anhydrase 2 Inhibitor Chlorothiazide Family 1 1
CFFAD443 Carbonic anhydrase 2 Inhibitor Ethinamate Family 1 0
CFFAD444 Catechol O-methyltransferase Inhibitor Tolcapone Family 7 19
CFFAD445 Catechol O-methyltransferase Inhibitor Entacapone Family 1 4
CFFAD446 Ceramide glucosyltransferase Inhibitor Miglustat Family 4 73
CFFAD447 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Enoxim... 1 0
CFFAD448 cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor Anag... 2 8
CFFAD449 cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Sildena... 17 40
CFFAD450 cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
CFFAD451 Hyaluronate family 4 186
CFFAD452 Cyclooxygenase Inhibitor Indomethacin Family 6 271
CFFAD453 Cyclooxygenase Inhibitor Ketorolac Family 3 40
CFFAD454 Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
CFFAD455 Cyclooxygenase Inhibitor Diclofenac Family 6 37
CFFAD456 Cyclooxygenase Inhibitor Flurbiprofen Family 18 294
CFFAD457 Cyclooxygenase Inhibitor Oxaprozin Family 33 450
CFFAD458 Prostaglandin G/H synthase 2 Inhibitor Ketoprofen Family 5 84
CFFAD459 Aromatase Inhibitor Testolactone Family 1 3
CFFAD460 Aromatase Inhibitor Letrozole Family 7 17
CFFAD461 14-alpha sterol demethylase Inhibitor Fluconazole Family 1 12
CFFAD462 14-alpha sterol demethylase Inhibitor Terconazole Family 4 46
CFFAD463 Dipeptidase 1 Inhibitor Cilastatin Family 1 17
CFFAD464 Peptide deformylase, mitochondrial Inhibitor Pyrimethamine Family 10 145
CFFAD465 Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
CFFAD466 Peptide deformylase, mitochondrial Inhibitor Trimetrexate Family 4 311
CFFAD467 Dihydroorotate dehydrogenase Inhibitor Leflunomide Family 1 1
CFFAD468 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 9 88
CFFAD469 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 2 3
CFFAD470 Dipeptidyl peptidase 4 Inhibitor Sitagliptin Family 6 4
CFFAD471 DNA (cytosine-5)-methyltransferase Inhibitor Azacitidine Family 2 4
CFFAD472 DNA polymerase Inhibitor Valaciclovir Family 2 0
CFFAD473 DNA polymerase Inhibitor Cytarabine Family 5 62
CFFAD474 DNA topoisomerase 1 Inhibitor Irinotecan Family 5 29
CFFAD475 DNA topoisomerase 2-beta Inhibitor Dexrazoxane Family 4 3
CFFAD476 DNA topoisomerase 2-beta Inhibitor Etoposide Family 3 29
CFFAD477 DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inh... 3 40
CFFAD478 DNA-dependent RNA polymerase beta subunit (Fragment) inhibitor... 2 2
CFFAD479 Epidermal growth factor receptor Ligand Gefitinib Family 26 600
CFFAD480 Farnesyl pyrophosphate synthase Inhibitor Risedronate Family 4 28
CFFAD481 Fatty acid synthase Inhibitor Cerulenin Family 1 1
CFFAD482 Fatty acid synthase subunit beta Inhibitor Pyrazinamide Family 1 4
CFFAD483 Fatty-acid amide hydrolase 1 Inhibitor Thiopental Family 2 4
CFFAD484 Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
CFFAD485 Fumarate reductase flavoprotein subunit Inhibitor Thiabendazol... 3 20
CFFAD486 Gamma-aminobutyric acid B receptor Ligand Gabapentin Family 4 26
CFFAD487 Gamma-aminobutyric acid receptor Ligand Piperazine Family 2 6
CFFAD488 Gamma-aminobutyric acid receptor subunit alpha-1 ligand Barbit... 4 0
CFFAD489 Gamma-aminobutyric acid receptor subunit alpha-1 ligand barbit... 4 1
CFFAD490 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Etomid... 3 10
CFFAD491 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Clobaz... 1 10
CFFAD492 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Meprob... 1 0
CFFAD493 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Methar... 2 0
CFFAD494 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Picrot... 2 2
CFFAD495 Gamma-aminobutyric acid receptor subunit alpha-1 ligand barbit... 1 0
CFFAD496 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Ethano... 1 0
CFFAD497 Gamma-aminobutyric acid receptor subunit alpha-1 ligand halog... 1 1
CFFAD498 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Methyp... 1 1
CFFAD499 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Flumaz... 10 100
CFFAD500 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Hexoba... 2 0
showing 1 to 500 of 1114. <<First <Prev Page 1 Next> Last>>

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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