CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

showing 1 to 134 of 134. <<First <Prev Page 1 Next> Last>>
show families with seed and member seed only

Browsing Family of Functional Category "Approved Drug"


IDNameSeedsMembers
CFFAD12 Aldehyde dehydrogenase inhibitor thiocarbonyl compound Disulfi... 1 0
CFFAD26 Nicotinic acetylcholine receptor ligand secondary aliphatic am... 3 0
CFFAD41 Solute carrier family 12 member 1 inhibitor aminobenzenesulfon... 1 0
CFFAD54 HIV reverse transcriptase inhibitor phosphonate derivative Fos... 2 0
CFFAD56 Alpha adrenergic receptor ligand dioxolane analog guanadrel fa... 1 0
CFFAD59 DNA binder platinum-based diaminocyclohexane analog Oxaliplati... 1 0
CFFAD70 Muscarinic acetylcholine receptor M3 ligand quinuclidine deriv... 1 0
CFFAD77 Benzodiazepine receptor ligand benzodiazepine analog Chlordiaz... 1 0
CFFAD98 50S ribosomal subunit Inhibitor macrolide ketolide antibiotics... 1 0
CFFAD103 Aminoglycoside antibiotics Micronomicin family 4 0
CFFAD109 Adrenergic neuron Inhibitor guanidine azocine analog Guanethid... 1 0
CFFAD122 Alpha-1 adrenergic receptor ligand ergot alkaloid Ergotamine F... 1 0
CFFAD124 ATP-sensitive inward rectifier potassium channel 10 Ligand Min... 1 0
CFFAD128 3-beta-hydroxysteroid dehydrogenase Inhibitor Trilostane Family 2 0
CFFAD132 5-aminoimidazole-4-carboxamidoribonucleotide (AICAR) transform... 1 0
CFFAD140 Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0
CFFAD158 Prostaglandin G/H synthase 2 inhibitor Oxicam derivative Pirox... 1 0
CFFAD169 Nicotinic acetylcholine receptor Ligand Cisatracurium Besylate... 1 0
CFFAD174 NMDA receptor Ligand Magnesium Family 2 0
CFFAD175 Acetyl-CoA carboxylase 2 Inhibitor Metformin Family 1 0
CFFAD200 Benzodiazepine receptor ligand benzodiazepine derivative Oxaze... 4 0
CFFAD235 D(2) dopamine receptor Ligand Bromocriptine Family 2 0
CFFAD272 Histamine H1 receptor Ligand Dimenhydrinate Family 1 0
CFFAD285 Neuronal acetylcholine receptor subunit alpha-2 ligand aminost... 2 0
CFFAD310 Alpha-1B adrenergic receptor Ligand Propericiazine Family 2 0
CFFAD318 Penicillin binding protein Inhibitor Ertapenem Family 1 0
CFFAD334 Penicillin binding protein Inhibitor Ticarcillin Family 2 0
CFFAD337 Retinoic acid receptor gamma Ligand Tazarotene Family 1 0
CFFAD360 Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 1 0
CFFAD361 Ryanodine receptor 2 Ligand Dantrolene Family 1 0
CFFAD372 Sodium channel protein type 5 subunit alpha Ligand Moricizine ... 1 0
CFFAD377 Solute carrier family 12 member 1 Inhibitor Chlorthalidone Family 1 0
CFFAD378 SUR1-type K(ATP) channel Ligand Gliclazide Family 2 0
CFFAD382 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 0
CFFAD387 DNA Binder Dacarbazine Family 1 0
CFFAD389 DNA Binder Carboplatin Family 1 0
CFFAD406 4-aminobutyrate aminotransferase, mitochondrial Inhibitor Viga... 1 0
CFFAD413 ADP/ATP translocase 1 Inhibitor Clodronate Family 1 0
CFFAD440 Carbonic anhydrase 2 Inhibitor Benzthiazide Family 1 0
CFFAD441 Carbonic anhydrase 2 Inhibitor Cyclothiazide Family 1 0
CFFAD443 Carbonic anhydrase 2 Inhibitor Ethinamate Family 1 0
CFFAD447 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Enoxim... 1 0
CFFAD472 DNA polymerase Inhibitor Valaciclovir Family 2 0
CFFAD488 Gamma-aminobutyric acid receptor subunit alpha-1 ligand Barbit... 4 0
CFFAD492 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Meprob... 1 0
CFFAD493 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Methar... 2 0
CFFAD495 Gamma-aminobutyric acid receptor subunit alpha-1 ligand barbit... 1 0
CFFAD496 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Ethano... 1 0
CFFAD500 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Hexoba... 2 0
CFFAD502 Glutamate receptor AMPA subtype Ligand Halothane Family 1 0
CFFAD533 Prostaglandin G/H synthase 1 Inhibitor Balsalazide Family 1 0
CFFAD539 Ribonucleoside-diphosphate reductase large subunit Inhibitor H... 1 0
CFFAD550 Thioredoxin reductase Inhibitor Auranofin Family 1 0
CFFAD555 Thyroid peroxidase Inhibitor Carbimazole Family 1 0
CFFAD556 Thyroid peroxidase Inhibitor Methimazole Family 1 0
CFFAD597 Solute carrier family 12 member 1 Inhibitor Potassium Chloride... 1 0
CFFAD634 70S prokaryotic ribosome Inhibitor Capreomycin Family 2 0
CFFAD636 Acetylcholinesterase Inhibitor Malathion Family 1 0
CFFAD653 ATP-sensitive inward rectifier potassium channel 10 Ligand Gly... 1 0
CFFAD657 ATP-sensitive inward rectifier potassium channel 10 ligand Sul... 1 0
CFFAD672 Calcium-activated potassium channel subunit alpha-1 ligand phe... 1 0
CFFAD680 Cholinesterase Inhibitor Hexafluronium Bromide Family 1 0
CFFAD681 Collagen Inhibitor Vitamin C Family 2 0
CFFAD692 DNA Binder Busulfan Family 1 0
CFFAD697 DNA Binder Altretamine Family 1 0
CFFAD700 DNA Binder Oxamniquine Family 1 0
CFFAD725 Guanylate cyclase Inhibitor Nitric Oxide Family 1 0
CFFAD742 Interleukin-1 beta Inhibitor Gallium Nitrate Family 1 0
CFFAD768 Neuronal acetylcholine receptor subunit alpha-4 Ligand Pentoli... 1 0
CFFAD770 NMDA receptor Ligand Ketamine Family 1 0
CFFAD773 Penicillin binding protein Inhibitor Cyclacillin Family 1 0
CFFAD787 Phospholipase A2 Inhibitor Hydrocortamate Family 1 0
CFFAD794 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 1 0
CFFAD797 Mineralocorticoid receptor ligand Spironolactone analog Drospi... 1 0
CFFAD811 Serum albumin Inhibitor Bismuth Family 1 0
CFFAD825 Vascular endothelial growth factor Inhibitor Pegaptanib Family 1 0
CFFAD828 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 0
CFFAD833 Urease subunit alpha Inhibitor Acetohydroxamic Acid Family 1 0
CFFAD840 Somatostatin Inhibitor Cysteamine Family 2 0
CFFAD851 Inositol 1,4,5-trisphosphate receptor type 3 Ligand Nitropruss... 1 0
CFFAD857 Bacterial outer membrane inhibitor polymyxin Colistimethate F... 1 0
CFFAD861 D-alanine--D-alanine ligase A Inhibitor Cycloserine Family 2 0
CFFAD871 D-alanyl-D-alanine carboxypeptidase Inhibitor Cephalosporin Fa... 1 0
CFFAD878 Gamma-aminobutyric acid A receptor Ligand Gaboxadol Family 3 0
CFFAD885 Inosine-5'-monophosphate dehydrogenase Inhibitor Mizoribine Fa... 1 0
CFFAD886 Fumarate reductase flavoprotein subunit Inhibitor Morantel Tar... 1 0
CFFAD887 Ribonucleoside-diphosphate reductase subunit M2 Inhibitor Mote... 1 0
CFFAD889 Fumarate reductase flavoprotein subunit Inhibitor Oxantel Pamo... 1 0
CFFAD891 D(2) dopamine receptor Ligand Quinagolide Family 2 0
CFFAD892 Potassium voltage-gated channel subfamily KQT member 4 Ligand ... 1 0
CFFAD895 Sodium channel protein type 5 subunit alpha Ligand Tetrodotoxi... 2 0
CFFAD903 5-hydroxytryptamine receptor 1A Ligand Treximet Family 1 0
CFFAD908 Cyclooxygenase Inhibitor Asasantin Family 1 0
CFFAD920 Peptide deformylase, mitochondrial Inhibitor MCB-3837 Family 1 0
CFFAD923 NMDA receptor Ligand Nitrous Oxide Family 1 0
CFFAD924 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor OZ... 1 0
CFFAD926 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor Py... 1 0
CFFAD932 Low affinity immunoglobulin gamma Fc region receptor II-a Liga... 1 0
CFFAD933 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 1 0
CFFAD936 Serotonin re-uptake Inhibitor Tianeptine Family 1 0
CFFAD939 Nicotinic acetylcholine receptor Ligand Varenicline Tartrate F... 1 0
CFFAD953 Tubulin Inhibitor Eribulin Family 1 0
CFFAD961 Spinosad family 1 0
CFFAD967 Ceftobiprole Medocaril family 1 0
CFFAD969 Sugammadex family 1 0
CFFAD973 benzoporphyrin derivative Talaporfin Family 2 0
CFFAD974 Hexyl Aminolevulinate family 1 0
CFFAD976 Biapenem family 1 0
CFFAD977 DNA Binder Amrubicin Hcl Family 3 0
CFFAD978 Gusperimus family 1 0
CFFAD990 cephalosporin Cefoselis Family 1 0
CFFAD992 Serine/threonine-protein kinase mTOR Inhibitor Zotarolimus Family 3 0
CFFAD999 DNA Binder Zinostatin Stimalamer Family 2 0
CFFAD1005 Ecabet family 1 0
CFFAD1009 Cefotiam Hexetil family 1 0
CFFAD1017 Flomoxef family 1 0
CFFAD1019 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor Fo... 1 0
CFFAD1021 Sultamicillin Tosilate family 1 0
CFFAD1022 Cefteram Pivoxil family 1 0
CFFAD1031 Deflazacort family 1 0
CFFAD1034 Cefbuperazone family 1 0
CFFAD1039 Astromycin family 1 0
CFFAD1049 Inosine Pranobex family 1 0
CFFAD1051 Sulprostone family 1 0
CFFAD1058 Rorifone family 1 0
CFFAD1077 Epicillin family 1 0
CFFAD1078 Fusafungine family 2 0
CFFAD1079 Tranylcypromine family 1 0
CFFAD1084 Sarkomycin family 1 0
CFFAD1085 DNA intercalative bis-alkylating agents Inhibitor Carzinophili... 1 0
CFFAD1086 Muscarinic acetylcholine receptor M1 Ligand Fesoterodine Fumar... 1 0
CFFAD1093 Serine/threonine-protein kinase B-raf Inhibitor Vemurafenib Fa... 2 0
CFFAD1099 Gamma-aminobutyric acid A receptor Ligand Fospropofol Family 1 0
CFFAD1114 IV iron Inhibitor Feraheme/ Rienso Family 1 0
showing 1 to 134 of 134. <<First <Prev Page 1 Next> Last>>

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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