CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

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Browsing Family of Functional Category "Approved Drug"


IDNameSeedsMembers
CFFAD501 Gamma-aminobutyric acid receptor subunit alpha-1 ligand benzod... 1 2
CFFAD502 Glutamate receptor AMPA subtype Ligand Halothane Family 1 0
CFFAD503 Glutamate receptor AMPA subtype Ligand Desflurane Family 1 1
CFFAD504 Glutamate receptor AMPA subtype Ligand Sevoflurane Family 1 8
CFFAD505 Glutathione S-transferase Inhibitor Praziquantel Family 5 167
CFFAD506 Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
CFFAD507 HBV polymerase Inhibitor Entecavir Family 1 2
CFFAD508 HBV polymerase inhibitor thymidine nucleoside analog Telbivudi... 12 128
CFFAD509 Histamine N-methyltransferase inhibitor aminoquinoline Amodiaq... 8 23
CFFAD510 HIV reverse transcriptase inhibitor thymidine nucleoside analo... 4 14
CFFAD511 HIV reverse transcriptase inhibitor guanosine analog Didanosin... 20 166
CFFAD512 HIV reverse transcriptase Inhibitor Abacavir Family 3 9
CFFAD513 HIV-1 protease Inhibitor Nelfinavir Family 11 26
CFFAD514 HIV-1 protease Inhibitor Atazanavir Family 16 58
CFFAD515 HIV-1 protease Inhibitor Lopinavir Family 4 25
CFFAD516 Reverse transcriptase Inhibitor Efavirenz Family 1 20
CFFAD517 Insulin-degrading enzyme inhibitor cyclic polypeptide Bacitrac... 30 259
CFFAD518 Isoleucine--tRNA ligase Inhibitor Mupirocin Family 3 3
CFFAD519 Multidrug resistance protein Inhibitor Benzquinamide Family 1 41
CFFAD520 Neuraminidase Inhibitor Oseltamivir Family 12 26
CFFAD521 Neuraminidase Inhibitor Zanamivir Family 6 7
CFFAD522 Niemann-Pick C1-like protein 1 Inhibitor Ezetimibe Family 1 4
CFFAD523 Noradrenergic re-uptake Inhibitor Phentermine Family 2 11
CFFAD524 Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
CFFAD525 Noradrenergic re-uptake Inhibitor Mazindol Family 16 24
CFFAD526 P2Y purinoceptor 12 Inhibitor Ticlopidine Family 2 4
CFFAD527 Potassium-transporting ATPase alpha chain 1 Inhibitor Pantopra... 1 3
CFFAD528 Prolyl 4-hydroxylase alpha subunit Inhibitor Hydralazine Family 1 4
CFFAD529 Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
CFFAD530 Prostaglandin G/H synthase 1 Inhibitor Suprofen Family 4 52
CFFAD531 Prostaglandin G/H synthase 1 Inhibitor Salicyclic Acid Family 3 39
CFFAD532 Prostaglandin G/H synthase 1 Inhibitor Bromfenac Family 1 4
CFFAD533 Prostaglandin G/H synthase 1 Inhibitor Balsalazide Family 1 0
CFFAD534 Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
CFFAD535 Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
CFFAD536 Prostaglandin G/H synthase 2 Inhibitor Tenoxicam Family 1 1
CFFAD537 Prostaglandin G/H synthase 2 Inhibitor Celecoxib Family 3 97
CFFAD538 Prostaglandin G/H synthase 2 Inhibitor Etoricoxib Family 2 99
CFFAD539 Ribonucleoside-diphosphate reductase large subunit Inhibitor H... 1 0
CFFAD540 Serotonin re-uptake Inhibitor Fluvoxamine Family 2 1
CFFAD541 Serotonin re-uptake inhibitor Dibenzazepine Clomipramine Family 2 23
CFFAD542 Signal transducer and activator of transcription 3 Inhibitor A... 5 249
CFFAD543 Solute carrier family 12 member 1 Inhibitor Torasemide Family 13 75
CFFAD544 Solute carrier family 12 member 1 Inhibitor Ethacrynic Acid Fa... 3 42
CFFAD545 Solute carrier family 12 member 3 Inhibitor Metolazone Family 2 2
CFFAD546 Squalene monooxygenase Inhibitor Naftifine Family 8 32
CFFAD547 Succinate-semialdehyde dehydrogenase, mitochondrial Inhibitor ... 1 2
CFFAD548 Synaptic vesicular amine transporter inhibitor indole alkaloi... 3 11
CFFAD549 Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
CFFAD550 Thioredoxin reductase Inhibitor Auranofin Family 1 0
CFFAD551 Prothrombin Inhibitor Argatroban Family 5 41
CFFAD552 Thymidylate synthase Inhibitor Raltitrexed Family 1 15
CFFAD553 Thymidylate synthase inhibitor thymidine nucleoside analog Flo... 8 48
CFFAD554 Thymidylate synthase Inhibitor Capecitabine Family 1 6
CFFAD555 Thyroid peroxidase Inhibitor Carbimazole Family 1 0
CFFAD556 Thyroid peroxidase Inhibitor Methimazole Family 1 0
CFFAD557 Tryptase Inhibitor Pentamidine Family 2 20
CFFAD558 Type-1 angiotensin II receptor Ligand Telmisartan Family 4 181
CFFAD559 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor Fo... 1 1
CFFAD560 Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
CFFAD561 Vitamin K epoxide reductase complex subunit 1 Inhibitor Phenin... 5 44
CFFAD562 Vitamin K epoxide reductase complex subunit 1 Inhibitor Acenoc... 2 46
CFFAD563 Xanthine dehydrogenase/oxidase Inhibitor Allopurinol Family 1 2
CFFAD564 4-hydroxyphenylpyruvate dioxygenase Inhibitor Nitisinone Family 4 43
CFFAD565 Cyclooxygenase Inhibitor Acetaminophen Family 2 42
CFFAD566 Prostaglandin G/H synthase 2 Inhibitor Etodolac Family 1 9
CFFAD567 Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
CFFAD568 Inosine-5'-monophosphate dehydrogenase 1 Inhibitor Azathioprin... 1 2
CFFAD569 Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
CFFAD570 DNA Binder Chlorambucil Family 3 11
CFFAD571 DNA Binder Clofazimine Family 1 2
CFFAD572 DNA Binder Mechlorethamine Family 2 1
CFFAD573 Oestrogen receptor Ligand Raloxifene Family 4 169
CFFAD574 Multidrug resistance-associated protein 1 Inhibitor Sulfinpyra... 1 3
CFFAD575 Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82
CFFAD576 Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
CFFAD577 Troponin C, slow skeletal and cardiac muscles Inhibitor Levosi... 1 4
CFFAD578 Troponin C, slow skeletal and cardiac muscles Inhibitor Dihydr... 1 1
CFFAD579 Glutamate receptor AMPA subtype ligand halogenated ether Enfl... 2 1
CFFAD580 4-aminobutyrate aminotransferase, mitochondrial Inhibitor Pyri... 3 16
CFFAD581 4-aminobutyrate aminotransferase, mitochondrial Inhibitor L-al... 3 23
CFFAD582 Prostaglandin G/H synthase 1 Inhibitor Gamma-homolinolenic Aci... 10 149
CFFAD583 Tyrosine 3-monooxygenase Inhibitor L-phenylalanine Family 19 144
CFFAD584 Acetylcholinesterase Inhibitor Pyridostigmine Family 5 197
CFFAD585 Angiotensin-converting enzyme Inhibitor Perindopril Family 3 9
CFFAD586 Coagulation factor X inhibitor low molecular weight heparins F... 3 1
CFFAD587 Corticosteroid-binding globulin inhibitor corticosteroid analo... 11 112
CFFAD588 Cyclooxygenase Inhibitor Meclofenamic Acid Family 4 11
CFFAD589 DNA topoisomerase 2-beta Inhibitor Nalidixic Acid Family 2 5
CFFAD590 Estrogen receptor beta Ligand Conjugated Estrogens Family 12 210
CFFAD591 Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
CFFAD592 Histamine receptor Ligand Histamine Phosphate Family 6 78
CFFAD593 Protein Tat Inhibitor Penicillamine Family 1 2
CFFAD594 Phospholipase A2 Inhibitor Quinacrine Family 13 95
CFFAD595 Prostacyclin receptor Ligand Dinoprost Tromethamine Family 2 1
CFFAD596 Receptor-type tyrosine-protein phosphatase S Ligand Etidronic ... 1 3
CFFAD597 Solute carrier family 12 member 1 Inhibitor Potassium Chloride... 1 0
CFFAD598 Thymidylate synthase Inhibitor Fluorouracil Family 3 10
CFFAD599 Tyrosinase Inhibitor Monobenzone Family 6 197
CFFAD600 D(2) dopamine receptor Ligand Sertindole Family 3 173
CFFAD601 D(2) dopamine receptor Ligand Chlorprothixene Family 1 5
CFFAD602 Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
CFFAD603 Muscarinic acetylcholine receptor Ligand Oxyphencyclimine Family 1 2
CFFAD604 Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
CFFAD605 Muscarinic acetylcholine receptor Ligand Anisotropine Methylbr... 1 1
CFFAD606 Androgen receptor ligand Anabolic steroid Dromostanolone Family 9 408
CFFAD607 Androgen receptor ligand anabolic androgenic steroid Testoster... 8 198
CFFAD608 Cholesterol side-chain cleavage enzyme, mitochondrial and Arom... 9 26
CFFAD609 D(2) dopamine receptor Ligand Zuclopenthixol Family 1 1
CFFAD610 D(2) dopamine receptor Ligand Amisulpride Family 1 2
CFFAD611 DNA Binder Hydroxystilbamidine Isethionate Family 1 1
CFFAD612 Epidermal growth factor receptor and Receptor tyrosine-protein... 9 65
CFFAD613 Oestrogen receptor ligand steroid Estradiol Family 18 147
CFFAD614 Progesterone receptor ligand steroidal progestin Etonogestrel ... 8 31
CFFAD615 Progesterone receptor Ligand Ethynodiol Diacetate Family 1 2
CFFAD616 Gamma-aminobutyric acid A receptor Ligand Acamprosate Family 1 2
CFFAD617 Histamine H1 receptor Ligand Doxylamine Family 2 91
CFFAD618 Progesterone receptor ligand steroidal progestin Medroxyproges... 6 20
CFFAD619 Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
CFFAD620 Noradrenergic re-uptake Inhibitor Protriptyline Family 3 25
CFFAD621 Tumor necrosis factor Inhibitor Thalidomide Family 3 50
CFFAD622 Aromatic-L-amino-acid decarboxylase Inhibitor Vitamin B6 Family 6 13
CFFAD623 Pyruvate decarboxylase Inhibitor Vitamin B1 Family 2 13
CFFAD624 Alpha-N-acetylglucosaminidase Inhibitor N-acetyl-d-glucosamine... 4 78
CFFAD625 Biliverdin reductase A and Solute carrier Family 23 member 2 i... 9 112
CFFAD626 Mannitol 2-dehydrogenase and Mannitol-1-phosphate 5-dehydrogen... 1 28
CFFAD627 Sodium channel protein type 10 subunit alpha and Sodium channe... 1 7
CFFAD628 Transient receptor potential cation channel subfamily A member... 1 32
CFFAD629 Fungal outer membrane inhibitor polyene Nystatin Family 4 4
CFFAD630 50S ribosomal subunit inhibitor macrolide Roxithromycin Family 2 1
CFFAD631 50S ribosomal subunit Inhibitor Retapamulin Family 1 1
CFFAD632 50S ribosomal subunit inhibitor macrolide Josamycin Family 6 6
CFFAD633 5-alpha reductase Inhibitor Azelaic Acid Family 11 166
CFFAD634 70S prokaryotic ribosome Inhibitor Capreomycin Family 2 0
CFFAD635 Acetylcholinesterase Inhibitor Ambenonium Family 4 71
CFFAD636 Acetylcholinesterase Inhibitor Malathion Family 1 0
CFFAD637 Acetylcholinesterase Inhibitor Isoflurophate Family 2 2
CFFAD638 Alpha adrenergic receptor Ligand Bevantolol Family 4 48
CFFAD639 Alpha-2 adrenergic receptor Ligand Guanfacine Family 4 9
CFFAD640 Alpha-2 adrenergic receptor Ligand Nicergoline Family 1 1
CFFAD641 Androgen receptor Ligand Oxandrolone Family 1 2
CFFAD642 Androgen receptor ligand steroidal progestin Cyproterone Family 2 5
CFFAD643 Type-1 angiotensin II receptor Ligand Olmesartan Family 13 65
CFFAD644 Type-1 angiotensin II receptor Ligand Eprosartan Family 36 176
CFFAD645 Angiotensin-converting enzyme Inhibitor Spirapril Family 17 86
CFFAD646 Angiotensin-converting enzyme inhibitor Dicarboxylate-containi... 7 54
CFFAD647 Oestrogen receptor ligand Dienestrol Family 35 440
CFFAD648 Arachidonate 5-lipoxygenase Inhibitor Diethylcarbamazine Family 1 1
CFFAD649 Bile salt export pump Inhibitor Probucol Family 1 36
CFFAD650 ATP-sensitive inward rectifier potassium channel 10 Ligand Mit... 1 6
CFFAD651 ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
CFFAD652 ATP-sensitive inward rectifier potassium channel 10 Ligand Gli... 2 45
CFFAD653 ATP-sensitive inward rectifier potassium channel 10 Ligand Gly... 1 0
CFFAD654 ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
CFFAD655 ATP-sensitive inward rectifier potassium channel 10 Ligand Chl... 1 2
CFFAD656 ATP-sensitive inward rectifier potassium channel 10 Ligand Gli... 1 2
CFFAD657 ATP-sensitive inward rectifier potassium channel 10 ligand Sul... 1 0
CFFAD658 Beta-lactamase Inhibitor Tazobactam Family 2 3
CFFAD659 Peptide deformylase, mitochondrial Inhibitor Trimethoprim Family 67 482
CFFAD660 DNA topoisomerase 2-beta Inhibitor Rosoxacin Family 1 5
CFFAD661 Benzodiazepine receptor ligand benzodiazepine derivative Fluni... 2 22
CFFAD662 Benzodiazepine receptor Ligand Clotiazepam Family 1 1
CFFAD663 Beta adrenergic receptor Ligand Bretylium Family 3 11
CFFAD664 Beta-1 adrenergic receptor Ligand Practolol Family 2 82
CFFAD665 Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
CFFAD666 Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
CFFAD667 Beta-2 adrenergic receptor Ligand Clenbuterol Family 2 19
CFFAD668 Beta-lactamase Inhibitor Clavulanate Family 2 1
CFFAD669 Tubulin beta chain Inhibitor Mebendazole Family 12 84
CFFAD670 Tubulin beta chain Inhibitor Albendazole Family 1 9
CFFAD671 Calcium-activated potassium channel subunit alpha-1 Ligand Chl... 2 15
CFFAD672 Calcium-activated potassium channel subunit alpha-1 ligand phe... 1 0
CFFAD673 Calmodulin Inhibitor Aprindine Family 1 4
CFFAD674 Carbonic anhydrase Inhibitor Diazoxide Family 1 2
CFFAD675 Carnitine O-palmitoyltransferase 1, muscle isoform Inhibitor P... 1 4
CFFAD676 Carnitine O-palmitoyltransferase 1, muscle isoform Inhibitor L... 1 5
CFFAD677 cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Papaver... 53 741
CFFAD678 Gastrin/cholecystokinin type B receptor ligand oligopeptide Ce... 35 209
CFFAD679 Cholinesterase Inhibitor Echothiophate Iodide Family 1 1
CFFAD680 Cholinesterase Inhibitor Hexafluronium Bromide Family 1 0
CFFAD681 Collagen Inhibitor Vitamin C Family 2 0
CFFAD682 Cyclooxygenase Inhibitor Icosapent Family 7 14
CFFAD683 Prostaglandin G/H synthase 2 Inhibitor Meloxicam Family 1 1
CFFAD684 Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
CFFAD685 Prostaglandin G/H synthase 2 Inhibitor Phenylbutazone Family 1 1
CFFAD686 Prostaglandin G/H synthase 2 Inhibitor Carprofen Family 1 5
CFFAD687 Cysteinyl leukotriene receptor 1 Ligand Cinalukast Family 1 2
CFFAD688 Cysteinyl leukotriene receptor 1 Ligand Pranlukast Family 21 72
CFFAD689 D(2) dopamine receptor Ligand Molindone Family 1 5
CFFAD690 D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
CFFAD691 DNA Binder Adenine Family 19 55
CFFAD692 DNA Binder Busulfan Family 1 0
CFFAD693 DNA Binder glucosamine derivative Streptozocin Family 1 3
CFFAD694 DNA Binder purine nucleoside Adenosine analog Nelarabine Family 2 10
CFFAD695 DNA Binder Procarbazine Family 8 358
CFFAD696 DNA Binder Pipobroman Family 1 1
CFFAD697 DNA Binder Altretamine Family 1 0
CFFAD698 DNA Binder Uracil Mustard Family 1 1
CFFAD699 DNA Binder Lomustine Family 1 1
CFFAD700 DNA Binder Oxamniquine Family 1 0
CFFAD701 DNA Binder Furazolidone Family 2 2
CFFAD702 DNA Binder Mitomycin Family 2 3
CFFAD703 DNA Binder Methoxsalen Family 10 1638
CFFAD704 DNA topoisomerase 2-beta Inhibitor Cinoxacin Family 2 17
CFFAD705 DNA topoisomerase 2-beta Inhibitor Novobiocin Family 1 3
CFFAD706 DNA topoisomerase 2-beta Inhibitor Lucanthone Family 2 7
CFFAD707 DNA-directed RNA polymerase subunit beta Inhibitor Rifaximin F... 1 1
CFFAD708 Dopamine receptor ligand norcamphene derivative Fencamfamine F... 3 41
CFFAD709 Elongation factor G Inhibitor Fusidic Acid Family 3 34
CFFAD710 Oestrogen receptor Ligand Chlorotrianisene Family 2 102
CFFAD711 Oestrogen receptor Ligand Mestranol Family 2 29
CFFAD712 Oestrogen receptor Ligand Danazol Family 2 6
CFFAD713 Farnesyl pyrophosphate synthase (Fragment) inhibitor Bisphosph... 2 2
CFFAD714 Farnesyl pyrophosphate synthase Inhibitor Ibandronate Family 2 3
CFFAD715 Farnesyl pyrophosphate synthase Inhibitor Zoledronate Family 3 31
CFFAD716 Fibroblast growth factor receptor 2 Ligand Pentosan Polysulfat... 1 2
CFFAD717 Follicle-stimulating hormone receptor Ligand Suramin Family 1 7
CFFAD718 Gamma-aminobutyric acid A receptor Ligand Bromazepam Family 2 60
CFFAD719 Gamma-aminobutyric acid A receptor Ligand Lindane Family 1 1
CFFAD720 Glucocorticoid receptor Ligand Fluticasone Propionate Family 3 5
CFFAD721 Glucocorticoid receptor ligand corticosteroid Prednisone Family 2 1
CFFAD722 Phospholipase A2 Inhibitor Halobetasol Propionate Family 3 5
CFFAD723 Glutamate dehydrogenase Inhibitor Hexachlorophene Family 1 6
CFFAD724 Growth hormone-releasing hormone receptor ligand polypeptide ... 14 34
CFFAD725 Guanylate cyclase Inhibitor Nitric Oxide Family 1 0
CFFAD726 Guanylate cyclase Inhibitor Isosorbide Dinitrate Family 2 2
CFFAD727 Guanylate cyclase Inhibitor Nitroglycerin Family 2 2
CFFAD728 Histamine H1 receptor Ligand Bepotastine Family 2 2
CFFAD729 Histamine H1 receptor Ligand Pheniramine Family 10 380
CFFAD730 Histamine H1 receptor Ligand Pemirolast Family 1 2
CFFAD731 Histamine H1 receptor Ligand Triprolidine Family 19 316
CFFAD732 Histamine H1 receptor Ligand Emedastine Family 5 115
CFFAD733 Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
CFFAD734 Histamine H1 receptor Ligand Epinastine Family 2 26
CFFAD735 Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
CFFAD736 Histamine H1 receptor Ligand Chlophedianol Family 4 46
CFFAD737 Histamine H2 receptor Ligand Betazole Family 1 2
CFFAD738 Histone deacetylase 1 Inhibitor Vorinostat Family 26 138
CFFAD739 DNA polymerase Inhibitor Cidofovir Family 1 1
CFFAD740 HIV-1 protease Inhibitor Tipranavir Family 25 10
CFFAD741 Matrix protein 2 inhibitor Adamantane derivative Rimantadine F... 3 1
CFFAD742 Interleukin-1 beta Inhibitor Gallium Nitrate Family 1 0
CFFAD743 Interleukin-1 beta Inhibitor Glucosamine Family 5 13
CFFAD744 Kappa-type opioid receptor Ligand Dezocine Family 36 46
CFFAD745 14-alpha sterol demethylase Inhibitor Posaconazole Family 1 5
CFFAD746 Maltase-glucoamylase, intestinal Inhibitor Voglibose Family 5 17
CFFAD747 Mineralocorticoid receptor ligand steroid progestogen analog D... 3 240
CFFAD748 Amine oxidase [flavin-containing] B Inhibitor Rasagiline Family 2 11
CFFAD749 Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
CFFAD750 Muscarinic acetylcholine receptor Ligand Cyclopentolate Family 10 11
CFFAD751 Muscarinic acetylcholine receptor Ligand Pilocarpine Family 3 29
CFFAD752 Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
CFFAD753 Muscarinic acetylcholine receptor Ligand Mepenzolate Family 35 11
CFFAD754 Muscarinic acetylcholine receptor M1 Ligand Oxyphenonium Family 12 5
CFFAD755 Muscarinic acetylcholine receptor M1 Ligand Dicyclomine Family 1 2
CFFAD756 Muscarinic acetylcholine receptor M2 Ligand Gallamine Triethio... 1 14
CFFAD757 Muscarinic acetylcholine receptor M3 Ligand Solifenacin Family 6 10
CFFAD758 Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45
CFFAD759 Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
CFFAD760 Muscarinic acetylcholine receptor M3 Ligand Succinylcholine Fa... 2 6
CFFAD761 Mu-type opioid receptor ligand opiate Alfentanil Family 1 2
CFFAD762 Mu-type opioid receptor Ligand Anileridine Family 3 18
CFFAD763 Mu-type opioid receptor Ligand Diphenoxylate Family 5 6
CFFAD764 Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
CFFAD765 Mu-type opioid receptor Ligand Alvimopan Family 32 325
CFFAD766 Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
CFFAD767 Neuronal acetylcholine receptor subunit alpha-4 Ligand Trimeth... 1 2
CFFAD768 Neuronal acetylcholine receptor subunit alpha-4 Ligand Pentoli... 1 0
CFFAD769 Neprilysin Inhibitor Candoxatril Family 1 3
CFFAD770 NMDA receptor Ligand Ketamine Family 1 0
CFFAD771 Noradrenergic re-uptake Inhibitor Maprotiline Family 6 33
CFFAD772 Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
CFFAD773 Penicillin binding protein Inhibitor Cyclacillin Family 1 0
CFFAD774 Penicillin binding protein Inhibitor Cephapirin Family 1 6
CFFAD775 Penicillin binding protein inhibitor β-lactam aminopenicillin ... 3 1
CFFAD776 Penicillin binding protein inhibitor β-lactam ureidopenicillin... 4 9
CFFAD777 Penicillin binding protein Inhibitor Penicillin V Family 1 25
CFFAD778 Penicillin binding protein Inhibitor Nafcillin Family 1 1
CFFAD779 Penicillin binding protein Inhibitor Meticillin Family 1 3
CFFAD780 Penicillin binding protein Inhibitor Cefacetrile Family 1 19
CFFAD781 Penicillin binding protein Inhibitor Pivmecillinam Family 2 2
CFFAD782 Penicillin binding protein inhibitor β-lactam cephalosporin Ce... 1 4
CFFAD783 Peptidoglycan synthase FtsI inhibitor cephalosporins Cefotiam ... 3 13
CFFAD784 Peptidoglycan synthase FtsI inhibitor β-lactam cephalosporin C... 2 6
CFFAD785 Peptidoglycan synthase FtsI Inhibitor Latamoxef Family 1 10
CFFAD786 Peroxisome proliferator-activated receptor alpha Ligand Bezafi... 2 17
CFFAD787 Phospholipase A2 Inhibitor Hydrocortamate Family 1 0
CFFAD788 Mannose-6-phosphate isomerase Inhibitor Sulfacetamide Family 19 117
CFFAD789 Mannose-6-phosphate isomerase Inhibitor Sulfoxone Family 3 20
CFFAD790 Mannose-6-phosphate isomerase Inhibitor Sulfanilamide Family 4 8
CFFAD791 Plasminogen Inhibitor Streptokinase Family 1 3
CFFAD792 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 1 1
CFFAD793 Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 5 60
CFFAD794 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 1 0
CFFAD795 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 8 15
CFFAD796 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 3 101
CFFAD797 Mineralocorticoid receptor ligand Spironolactone analog Drospi... 1 0
CFFAD798 Progesterone receptor Ligand Desogestrel Family 2 5
CFFAD799 Progesterone receptor Ligand Norgestimate Family 1 1
CFFAD800 Prostacyclin receptor Ligand Epoprostenol Family 4 33
CFFAD801 Prostacyclin receptor Ligand Treprostinil Family 1 2
CFFAD802 Prostaglandin F2-alpha receptor Ligand Latanoprost Family 4 18
CFFAD803 Prostaglandin F2-alpha receptor Ligand Bimatoprost Family 1 4
CFFAD804 Prothrombin Inhibitor Ximelagatran Family 5 48
CFFAD805 Renin Inhibitor Aliskiren Family 28 107
CFFAD806 Renin Inhibitor Remikiren Family 100 126
CFFAD807 Serotonin re-uptake Inhibitor Dexfenfluramine Family 6 31
CFFAD808 Serum albumin Inhibitor Gadobenate Dimeglumine Family 1 2
CFFAD809 Serum albumin Inhibitor Iodipamide Family 2 23
CFFAD810 Serum albumin Inhibitor Sodium Lauryl Family 3 12
CFFAD811 Serum albumin Inhibitor Bismuth Family 1 0
CFFAD812 Sodium channel Ligand Permethrin Family 1 25
CFFAD813 Squalene monooxygenase Inhibitor Tolnaftate Family 1 4
CFFAD814 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 1 5
CFFAD815 Dihydropterin pyrophosphokinase-dihydropteroate synthase inhib... 4 14
CFFAD816 Thymidylate synthase Inhibitor Leucovorin/5-fluorouracil Family 9 83
CFFAD817 Thyroid peroxidase and Type I iodothyronine deiodinase Inhibit... 1 3
CFFAD818 Toll-like receptor 7 Ligand Docosanol Family 3 68
CFFAD819 Translocator protein Inhibitor Chlormezanone Family 1 1
CFFAD820 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 9
CFFAD821 Tubulin Inhibitor Colchicine Family 4 160
CFFAD822 Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
CFFAD823 Type-1 angiotensin II receptor Ligand Saprisartan Family 1 12
CFFAD824 Type-1 angiotensin II receptor Ligand Tasosartan Family 10 29
CFFAD825 Vascular endothelial growth factor Inhibitor Pegaptanib Family 1 0
CFFAD826 Voltage-dependent calcium channel gamma-1 subunit Ligand Dilti... 2 27
CFFAD827 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 3 5
CFFAD828 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 0
CFFAD829 14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
CFFAD830 14-alpha sterol demethylase inhibitor imidazole derivative Ti... 2 2
CFFAD831 14-alpha sterol demethylase Inhibitor Voriconazole Family 1 5
CFFAD832 Vitamin K-dependent gamma-carboxylase Inhibitor Anisindione Fa... 3 243
CFFAD833 Urease subunit alpha Inhibitor Acetohydroxamic Acid Family 1 0
CFFAD834 Integral membrane protein LmrP Inhibitor Quinupristin Family 1 2
CFFAD835 NADH-ubiquinone oxidoreductase chain 3 Inhibitor Nadh Family 4 11
CFFAD836 Solute carrier family 22 member 6 Inhibitor Probenecid Family 2 22
CFFAD837 Parasitic pyruvate:ferredoxin oxidoreductase Inhibitor Nitazox... 1 2
CFFAD838 Peptidyl-transferase domain of the bacterial ribosome Inhibito... 1 1
CFFAD839 Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
CFFAD840 Somatostatin Inhibitor Cysteamine Family 2 0
CFFAD841 Cycloinulo-oligosaccharide fructanotransferase Inhibitor Inuli... 1 4
CFFAD842 Cytochrome P450 2D6 Inhibitor Glutethimide Family 1 1
CFFAD843 D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
CFFAD844 Estramustine binding protein Inhibitor Estramustine Family 1 1
CFFAD845 Folate receptor gamma Ligand Folic Acid Family 4 100
CFFAD846 Food vacuoles Inhibitor Mefloquine Family 2 25
CFFAD847 Solute carrier family 52, riboflavin transporter, member 2 Inh... 2 3
CFFAD848 Hemoglobin subunit alpha Inhibitor Iron Dextran Family 1 1
CFFAD849 Hemoglobin subunit alpha Inhibitor Iron Family 1 2
CFFAD850 Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
CFFAD851 Inositol 1,4,5-trisphosphate receptor type 3 Ligand Nitropruss... 1 0
CFFAD852 26S proteasome Inhibitor Bortezomib Family 7 65
CFFAD853 Atrial natriuretic peptide receptor 1 Ligand Nesiritide Family 6 111
CFFAD854 Bacterial outer membrane Inhibitor Polymyxin B Family 17 181
CFFAD855 Bacterial outer membrane inhibitor polymyxin Colistin Family 26 160
CFFAD856 Bacterial outer membrane Inhibitor Daptomycin Family 6 50
CFFAD857 Bacterial outer membrane inhibitor polymyxin Colistimethate F... 1 0
CFFAD858 Bacterial outer membrane Inhibitor Vancomycin Family 8 1
CFFAD859 Fungal outer membrane Inhibitor Haloprogin Family 1 7
CFFAD860 Malignant cancer cells Inhibitor Arsenic Trioxide Family 1 1
CFFAD861 D-alanine--D-alanine ligase A Inhibitor Cycloserine Family 2 0
CFFAD862 Methylmalonyl-CoA mutase, mitochondrial Inhibitor Hydroxocobal... 2 4
CFFAD863 Peroxisome proliferator-activated receptor gamma Ligand Trogli... 2 28
CFFAD864 Prostaglandin G/H synthase 2 Inhibitor Rofecoxib Family 3 46
CFFAD865 Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
CFFAD866 Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
CFFAD867 Histamine H1 receptor Ligand Antazoline Family 5 57
CFFAD868 Ornithine decarboxylase Inhibitor Eflornithine Family 3 4
CFFAD869 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Barbit... 1 1
CFFAD870 Multidrug resistance-associated protein 1 Inhibitor Biricodar ... 6 40
CFFAD871 D-alanyl-D-alanine carboxypeptidase Inhibitor Cephalosporin Fa... 1 0
CFFAD872 Peroxisome proliferator-activated receptor alpha Ligand Ciprof... 1 5
CFFAD873 Amine oxidase [flavin-containing] A Inhibitor Clorgyline Family 3 6
CFFAD874 D(2) dopamine receptor Ligand Dapotum D Family 1 1
CFFAD875 Serum albumin Inhibitor Ebselen Family 3 62
CFFAD876 Aldose reductase Inhibitor Epalrestat Family 2 12
CFFAD877 1-deoxy-D-xylulose-5-phosphate reductoisomerase Inhibitor Fosm... 1 2
CFFAD878 Gamma-aminobutyric acid A receptor Ligand Gaboxadol Family 3 0
CFFAD879 Proto-oncogene tyrosine-protein kinase Src Inhibitor Herbimyci... 5 20
CFFAD880 Aldehyde oxidase Inhibitor Isovanillin Family 6 429
CFFAD881 5-hydroxytryptamine 2 receptor Ligand Ketanserin Family 10 253
CFFAD882 High affinity nerve growth factor receptor Ligand Lestaurtinib... 6 126
CFFAD883 Histamine H1 receptor Ligand Mepyramine Family 5 65
CFFAD884 Histamine H1 receptor Ligand Mizolastine Family 14 603
CFFAD885 Inosine-5'-monophosphate dehydrogenase Inhibitor Mizoribine Fa... 1 0
CFFAD886 Fumarate reductase flavoprotein subunit Inhibitor Morantel Tar... 1 0
CFFAD887 Ribonucleoside-diphosphate reductase subunit M2 Inhibitor Mote... 1 0
CFFAD888 SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
CFFAD889 Fumarate reductase flavoprotein subunit Inhibitor Oxantel Pamo... 1 0
CFFAD890 SUR2-type K(ATP) channel Ligand Pinacidil Family 1 8
CFFAD891 D(2) dopamine receptor Ligand Quinagolide Family 2 0
CFFAD892 Potassium voltage-gated channel subfamily KQT member 4 Ligand ... 1 0
CFFAD893 Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
CFFAD894 5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
CFFAD895 Sodium channel protein type 5 subunit alpha Ligand Tetrodotoxi... 2 0
CFFAD896 Inosine-5'-monophosphate dehydrogenase Inhibitor Tiazofurin Fa... 1 1
CFFAD897 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI Inhibitor T... 6 28
CFFAD898 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodi... 1 4
CFFAD899 Endothelin-1 receptor Ligand Ambrisentan Family 12 40
CFFAD900 Xanthine dehydrogenase/oxidase Inhibitor Febuxostat Family 1 6
CFFAD901 Oestrogen receptor Ligand Lasofoxifene Family 19 152
CFFAD902 Thrombopoietin receptor Ligand Revolade/promacta Family 2 20
CFFAD903 5-hydroxytryptamine receptor 1A Ligand Treximet Family 1 0
CFFAD904 Epidermal growth factor receptor and Receptor tyrosine-protein... 3 140
CFFAD905 Sodium/potassium-transporting ATPase subunit alpha-1 Inhibitor... 3 5
CFFAD906 Dihydroorotate dehydrogenase inhibitor sesquiterpene lactone A... 2 1
CFFAD907 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor Ar... 4 5
CFFAD908 Cyclooxygenase Inhibitor Asasantin Family 1 0
CFFAD909 Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
CFFAD910 Bacterial outer membrane Inhibitor Cefozopran Family 2 1
CFFAD911 Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
CFFAD912 Reverse transcriptase Inhibitor Etravirine Family 1 2
CFFAD913 Bacterial outer membrane Inhibitor Faropenem Family 1 1
CFFAD914 Alpha-2 adrenergic receptor Ligand Guanfacine Extended Release... 5 45
CFFAD915 Growth hormone receptor Ligand Ibutamoren Family 7 41
CFFAD916 Omega 1 Benzodiazepine receptor Ligand Indiplon Family 4 25
CFFAD917 Acyl-CoA desaturase Inhibitor Isoxyl Family 5 62
CFFAD918 Somatostatin receptor type 2 ligand octapeptide Lanreotide Family 93 156
CFFAD919 Sodium/potassium-transporting ATPase subunit alpha-1 inhibitor... 1 1
CFFAD920 Peptide deformylase, mitochondrial Inhibitor MCB-3837 Family 1 0
CFFAD921 Muscarinic acetylcholine receptor Ligand Mebeverine Family 2 27
CFFAD922 Insulin receptor Ligand Meglitinides Family 9 25
CFFAD923 NMDA receptor Ligand Nitrous Oxide Family 1 0
CFFAD924 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor OZ... 1 0
CFFAD925 Sarcoplasmic/endoplasmic reticulum calcium ATPase inhibitor qu... 2 60
CFFAD926 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor Py... 1 0
CFFAD927 DNA topoisomerase 2-beta Inhibitor Quinolones Family 2 2
CFFAD928 Integrase Inhibitor Raltegravir Family 3 3
CFFAD929 Sodium channel Ligand Rufinamide Family 1 3
CFFAD930 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Simv... 4 27
CFFAD931 Endothelin-1 receptor Ligand Sitaxsentan Family 6 24
CFFAD932 Low affinity immunoglobulin gamma Fc region receptor II-a Liga... 1 0
CFFAD933 Dihydropterin pyrophosphokinase-dihydropteroate synthase Inhib... 1 0
CFFAD934 5-hydroxytryptamine receptor 4 Ligand Tegaserod Family 2 2
CFFAD935 16S rRNA Inhibitor Tetracyclines Family 2 18
CFFAD936 Serotonin re-uptake Inhibitor Tianeptine Family 1 0
CFFAD937 Vasopressin V2 receptor Ligand Tolvaptan Family 1 4
CFFAD938 Histamine H1 receptor Ligand Tranilast Family 5 125
CFFAD939 Nicotinic acetylcholine receptor Ligand Varenicline Tartrate F... 1 0
CFFAD940 Prothrombin Inhibitor Ximelegatran Family 8 157
CFFAD941 mRNA of IE2 region of cytomegalovirus Inhibitor Fomivirsen Family 10 2
CFFAD942 Prostaglandin G/H synthase 2 Inhibitor Benzisoxazole Derivativ... 8 38
CFFAD943 Thymidylate synthase Inhibitor Flucytosine Family 1 2
CFFAD944 Retinoic acid receptor and Retinoid X receptor Ligand Vitamin ... 1 8
CFFAD945 Dipeptidyl peptidase 4 Inhibitor Vildagliptin Family 5 7
CFFAD946 Diacylglycerol O-acyltransferase 2 and Hydroxycarboxylic acid ... 4 45
CFFAD947 P2Y purinoceptor 12 Inhibitor Prasugrel Family 1 1
CFFAD948 Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
CFFAD949 G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
CFFAD950 Carbamoyl-phosphate synthase [ammonia], mitochondrial Inhibito... 5 13
CFFAD951 Histamine H1 receptor Ligand Alcaftadine Family 1 4
CFFAD952 Prothrombin Inhibitor Dabigatran Family 7 182
CFFAD953 Tubulin Inhibitor Eribulin Family 1 0
CFFAD954 Tubulin Inhibitor Ixabepilone Family 1 3
CFFAD955 Smoothened homolog Inhibitor Vismodegib Family 1 19
CFFAD956 ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
CFFAD957 20S proteasome Inhibitor Carfilzomib Family 5 17
CFFAD958 ribosome Inhibitor Omacetaxine Mepesuccinate Family 2 3
CFFAD959 Ingenol Mebutate family 6 1
CFFAD960 Cystic fibrosis transmembrane conductance regulator and Anocta... 12 74
CFFAD961 Spinosad family 1 0
CFFAD962 RNA polymerase Inhibitor Fidaxomicin Family 1 1
CFFAD963 cephalosporin Ceftaroline Family 2 9
CFFAD964 Mifamurtide family 3 3
CFFAD965 Zucapsacin family 7 177
CFFAD966 Nalfurafine Hcl family 33 107
CFFAD967 Ceftobiprole Medocaril family 1 0
CFFAD968 Dienogest family 1 3
CFFAD969 Sugammadex family 1 0
CFFAD970 Trabectedin family 1 2
CFFAD971 Hydroxyprogesterone family 4 37
CFFAD972 Glutamine receptor Ligand L-alanyl-l-glutamine Family 3 101
CFFAD973 benzoporphyrin derivative Talaporfin Family 2 0
CFFAD974 Hexyl Aminolevulinate family 1 0
CFFAD975 Temoporfin family 1 3
CFFAD976 Biapenem family 1 0
CFFAD977 DNA Binder Amrubicin Hcl Family 3 0
CFFAD978 Gusperimus family 1 0
CFFAD979 Fudosteine family 4 34
CFFAD980 benzoporphyrin derivative Verteporfin Family 1 1
CFFAD981 Trimegestone family 7 25
CFFAD982 Hidrosmin family 14 61
CFFAD983 thyrotropin-releasing hormone analog Taltirelin Family 7 29
CFFAD984 Egualen family 1 1
CFFAD985 Kinetin family 2 39
CFFAD986 Cathelicidin antimicrobial peptide Inhibitor Colforsin Daropat... 2 25
CFFAD987 Arglabin family 4 38
CFFAD988 Mobenakin family 2 5
CFFAD989 Dermatan family 1 11
CFFAD990 cephalosporin Cefoselis Family 1 0
CFFAD991 5-hydroxytryptamine receptor ligand azapirone derivative Tando... 7 16
CFFAD992 Serine/threonine-protein kinase mTOR Inhibitor Zotarolimus Family 3 0
CFFAD993 Prezatide Copper Acetate family 4 86
CFFAD994 Betain Anhydrous family 3 9
CFFAD995 Thymalfasin family 10 31
CFFAD996 Tirilazad Mesylate family 1 8
CFFAD997 Angiotensin-converting enzyme Inhibitor Temocapril Family 4 15
CFFAD998 Dopamine receptor Ligand Docarpamine Family 1 8
CFFAD999 DNA Binder Zinostatin Stimalamer Family 2 0
CFFAD1000 Unoprostone Isopropyl Ester family 1 3
showing 501 to 1000 of 1114. <<First <Prev Page 2 Next> Last>>

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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