CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

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Browsing Family of Functional Category "Clinical Trial Drug"


IDNameSeedsMembers
CFFCD1 Tyrosine-protein phosphatase non-receptor type 6 Ligand Sodium... 1 0
CFFCD2 Stromelysin-1 Inhibitor PG-530742 Family 4 23
CFFCD3 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 1 1
CFFCD4 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 5 81
CFFCD5 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 6 1
CFFCD6 Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Family 2 75
CFFCD7 Cyclin-dependent kinase 2 and Cyclin-dependent kinase 7 Inhibi... 11 38
CFFCD8 RAC-gamma serine/threonine-protein kinase and Ribosomal protei... 3 5
CFFCD9 Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
CFFCD10 Integrin alpha-4 Inhibitor R1295 Family 18 59
CFFCD11 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 3 15
CFFCD12 Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
CFFCD13 Cathepsin G and Neutrophil elastase Inhibitor Dermolastin Family 1 15
CFFCD14 Platelet-activating factor acetylhydrolase Inhibitor Gsk 65903... 1 0
CFFCD15 Mitogen-activated protein kinase 12 Inhibitor SB681323 Family 1 0
CFFCD16 Transient receptor potential cation channel subfamily V member... 15 158
CFFCD17 Transient receptor potential cation channel subfamily V member... 12 108
CFFCD18 Histamine H3 receptor Ligand ABT-239 Family 8 20
CFFCD19 Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Family 8 56
CFFCD20 Nitric oxide synthase, endothelial Inhibitor Acclaim Family 2 15
CFFCD21 Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
CFFCD22 Heat shock protein HSP 90-alpha Inhibitor Alvespimycin Family 7 0
CFFCD23 Arachidonate 5-lipoxygenase-activating protein Inhibitor AM803... 1 0
CFFCD24 C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
CFFCD25 C-X-C chemokine receptor type 4 Ligand AMD-3100 Family 3 6
CFFCD26 Leukotriene B4 receptor 1 Ligand Amelubant Family 1 0
CFFCD27 Melanin-concentrating hormone receptor 1 Ligand Amg 076 Family 2 8
CFFCD28 Transient receptor potential cation channel subfamily V member... 42 32
CFFCD29 Transient receptor potential cation channel subfamily V member... 2 0
CFFCD30 Tumor necrosis factor Inhibitor AN0128 Family 1 0
CFFCD31 Cholesteryl ester transfer protein Inhibitor Anacetrapib Family 3 63
CFFCD32 B2 bradykinin receptor Ligand Anatibant Family 49 15
CFFCD33 Glucose-dependent insulinotropic receptor Ligand APD668 Family 3 8
CFFCD34 Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
CFFCD35 Kinesin-like protein KIF11 Inhibitor ARRY-520 Family 1 3
CFFCD36 Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
CFFCD37 Heat shock protein HSP 90-alpha Inhibitor AT13387 Family 1 3
CFFCD38 Cyclin-dependent kinase 2 Inhibitor AT7519 Family 2 14
CFFCD39 Aurora kinase B and Aurora kinase A Inhibitor AT9283 Family 2 0
CFFCD40 Farnesyltransferase beta subunit, putative Inhibitor AZD3409 F... 2 2
CFFCD41 Transient receptor potential cation channel subfamily V member... 16 295
CFFCD42 Purine nucleoside phosphorylase Inhibitor BCX-34 Family 2 31
CFFCD43 Purine nucleoside phosphorylase Inhibitor Forodesine Family 11 54
CFFCD44 Histidine decarboxylase Inhibitor Bf-derm1 Family 12 95
CFFCD45 Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Family 15 81
CFFCD46 Mitogen-activated protein kinase 12 Inhibitor Birb 796 Family 20 43
CFFCD47 Microsomal triglyceride transfer protein large subunit Inhibit... 15 208
CFFCD48 Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
CFFCD49 Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 1 4
CFFCD50 Mitogen-activated protein kinase 8 Inhibitor CC-401 Family 1 0
CFFCD51 C-C chemokine receptor type 2 Ligand CCX915 Family 3 25
CFFCD52 Lysosomal alpha-glucosidase Inhibitor Celgosivir Family 1 1
CFFCD53 Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
CFFCD54 Neurotensin receptor type 1 Ligand CGX-1160 Family 1 0
CFFCD55 Puromycin-sensitive aminopeptidase Inhibitor CHR-2797 Family 1 2
CFFCD56 Histamine H3 receptor Ligand Cipralisant Family 36 70
CFFCD57 Macrophage migration inhibitory factor Inhibitor COR100140 Family 1 0
CFFCD58 Farnesyltransferase beta subunit, putative Inhibitor Cp-609,75... 2 11
CFFCD59 Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 29 421
CFFCD60 Serine/threonine-protein kinase PLK1 Inhibitor CYC-800 Family 1 0
CFFCD61 Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Family 32 52
CFFCD62 Platelet-activating factor acetylhydrolase Inhibitor Darapladi... 15 3
CFFCD63 Cholecystokinin receptor type A Ligand Dexloxiglumide Family 5 59
CFFCD64 Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 3 206
CFFCD65 Prostaglandin E2 receptor EP3 subtype Ligand DG041 Family 9 16
CFFCD66 Leukotriene A-4 hydrolase Inhibitor DG051 Family 2 8
CFFCD67 Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
CFFCD68 Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
CFFCD69 Cadherin-2 Inhibitor Exherin Family 2 9
CFFCD70 Egl nine homolog 2 Inhibitor FG-4592 Family 1 4
CFFCD71 Histone deacetylase 4 Inhibitor FK-228 Family 5 1
CFFCD72 Cyclin-dependent kinase 2 Inhibitor Flavopiridol Family 4 124
CFFCD73 Cholecystokinin receptor type A Ligand Gi 181771 Family 3 18
CFFCD74 Nuclear factor NF-kappa-B p100 subunit Inhibitor GMX1777 Family 3 7
CFFCD75 Telomerase protein component 1 Inhibitor GRN163L Family 5 29
CFFCD76 Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Family 40 84
CFFCD77 Centromere-associated protein E Inhibitor GSK-923295 Family 1 0
CFFCD78 Glycine receptor subunit beta Ligand Gw 468816 Family 4 67
CFFCD79 Hypoxia-inducible factor 1-alpha Inhibitor Hif-1alpha Family 7 107
CFFCD80 Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Family 3 58
CFFCD81 B2 bradykinin receptor Ligand Icatibant Family 9 27
CFFCD82 Microsomal triglyceride transfer protein large subunit Inhibit... 1 0
CFFCD83 Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor INCB1... 4 5
CFFCD84 C-C chemokine receptor type 2 Ligand INCB3284 Family 1 0
CFFCD85 Heat shock protein HSP 90-alpha Inhibitor IPI-504 Family 3 5
CFFCD86 Glucosylceramidase Inhibitor Isofagomine Tartrate Family 1 0
CFFCD87 Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
CFFCD88 Motilin receptor Ligand KOS-2187 Family 1 1
CFFCD89 Poly [ADP-ribose] polymerase 1 Inhibitor KU-0059436 Family 21 45
CFFCD90 B2 bradykinin receptor Ligand Labradimil Family 1 1
CFFCD91 Squalene synthase Inhibitor Lapaquistat Acetate Family 27 38
CFFCD92 Serine/threonine-protein kinase PLK1 Inhibitor LC-445 Family 2 0
CFFCD93 Cholecystokinin receptor type A Ligand Lintitript Family 1 0
CFFCD94 Nitric oxide synthase, endothelial Inhibitor L-NAME Family 3 2
CFFCD95 Nitric oxide synthase, endothelial Inhibitor L-NMMA Family 7 19
CFFCD96 Farnesyltransferase beta subunit, putative Inhibitor Lonafarni... 36 87
CFFCD97 Glucokinase Inhibitor Lonidamine Family 1 7
CFFCD98 Leukotriene B4 receptor 1 Ligand Ltb 019 Family 3 35
CFFCD99 Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
CFFCD100 Multidrug resistance protein 3 Inhibitor LY335979 Family 1 3
CFFCD101 Metabotropic glutamate receptor 3 Ligand LY354740 Family 7 12
CFFCD102 Metabotropic glutamate receptor 3 Ligand LY404039 Family 4 0
CFFCD103 Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
CFFCD104 Fructose-1,6-bisphosphatase 1 Inhibitor MB07803 Family 3 55
CFFCD105 Peroxisome proliferator-activated receptor delta Ligand MBX-80... 2 2
CFFCD106 Neurotensin receptor type 1 Ligand Meclinertant Family 3 11
CFFCD107 Motilin receptor Ligand Mitemcinal Family 5 0
CFFCD108 Aurora kinase A Inhibitor MLN8054 Family 2 5
CFFCD109 Hepatocyte growth factor receptor and Mast/stem cell growth fa... 1 0
CFFCD110 Histone deacetylase 1 Inhibitor MS-275 Family 4 41
CFFCD111 C-X-C chemokine receptor type 4 Ligand MSX-122 Family 1 0
CFFCD112 Corticotropin-releasing factor receptor 1 Ligand NBI-34041 Family 1 0
CFFCD113 Corticotropin-releasing factor receptor 1 Ligand NBI-37582 Family 2 0
CFFCD114 Melanin-concentrating hormone receptor 1 Ligand NGD-4715 Family 1 1
CFFCD115 Transient receptor potential cation channel subfamily V member... 15 457
CFFCD116 Phosphodiesterase and Thromboxane-A synthase Inhibitor NM-702 ... 1 0
CFFCD117 Nitric oxide synthase, brain Inhibitor NXN-188 Family 1 7
CFFCD118 Cathepsin K Inhibitor Odanacatib Family 33 84
CFFCD119 Calcitonin gene-related peptide 1 Inhibitor Olcegepant Family 6 9
CFFCD120 Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
CFFCD121 Prostaglandin E2 receptor EP4 subtype Ligand ONO-4819 Family 11 16
CFFCD122 Neuromedin-K receptor Ligand Osanetant Family 38 192
CFFCD123 RAC-gamma serine/threonine-protein kinase Inhibitor Perifosine... 1 3
CFFCD124 Nuclear factor NF-kappa-B p100 subunit Inhibitor PG-490-88 Family 3 0
CFFCD125 Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
CFFCD126 Heparanase Inhibitor PI-88 Family 2 2
CFFCD127 Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor P... 1 0
CFFCD128 Glucokinase Inhibitor PSN-101 Family 1 0
CFFCD129 Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
CFFCD130 Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
CFFCD131 Thioredoxin Inhibitor PX-12 Family 1 5
CFFCD132 Histone deacetylase 1 Inhibitor PXD101 Family 3 24
CFFCD133 Integrin beta-1 Inhibitor R411 Family 33 44
CFFCD134 Tyrosine-protein kinase SYK Inhibitor R788 Family 3 7
CFFCD135 Cathepsin K Inhibitor Relacatib Family 26 32
CFFCD136 Signal transducer and activator of transcription 3 Inhibitor R... 3 3
CFFCD137 B-lymphocyte antigen CD19 Inhibitor SAR3419 Family 1 0
CFFCD138 Neuromedin-K receptor Ligand SB222200 Family 17 235
CFFCD139 Transient receptor potential cation channel subfamily V member... 6 66
CFFCD140 Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
CFFCD141 Mitogen-activated protein kinase 12 Inhibitor SCIO-469 Family 1 7
CFFCD142 Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
CFFCD143 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD144 Hepatocyte growth factor receptor Ligand SGX523 Family 1 15
CFFCD145 Heat shock protein HSP 90-alpha Inhibitor SNX-5422 Family 2 2
CFFCD146 Substance-K receptor Ligand Sr 144190 Family 2 0
CFFCD147 Coagulation factor X and Prothrombin Inhibitor SR-123781A Family 4 1
CFFCD148 NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
CFFCD149 Interleukin-12 subunit alpha Inhibitor STA-5326 Family 2 51
CFFCD150 Heat shock protein HSP 90-alpha Inhibitor STA-9090 Family 2 0
CFFCD151 Steryl-sulfatase Inhibitor Stx 64 Family 7 160
CFFCD152 C-X-C chemokine receptor type 3 Ligand T487 Family 1 0
CFFCD153 Transcription factor AP-1 Inhibitor T-5224 Family 1 0
CFFCD154 Neuromedin-K receptor Ligand Talnetant Family 3 49
CFFCD155 72 kDa type IV collagenase Inhibitor Tanomastat Family 1 4
CFFCD156 Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
CFFCD157 Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
CFFCD158 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 13
CFFCD159 Fibroblast growth factor receptor 3 Ligand TKI258 Family 2 1
CFFCD160 Toll-like receptor 9 Ligand TLR9 Agonist Family 8 8
CFFCD161 Cholesteryl ester transfer protein Inhibitor Torcetrapib Family 1 8
CFFCD162 Coagulation factor IX Inhibitor TTP889 Family 1 0
CFFCD163 Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
CFFCD164 Phospholipase A2, membrane associated Inhibitor Varespladib Fa... 37 190
CFFCD165 Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 28 56
CFFCD166 Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
CFFCD167 Mitogen-activated protein kinase 12 Inhibitor VX-745 Family 1 16
CFFCD168 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD169 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD170 Hepatocyte growth factor receptor and Vascular endothelial gro... 28 178
CFFCD171 Farnesyltransferase beta subunit, putative Inhibitor Zarnestra... 10 56
CFFCD172 Serine/threonine-protein kinase PLK1 Inhibitor Zk-thiazolidino... 1 0
CFFCD173 Muscarinic acetylcholine receptor M1 Ligand Talsaclidine Isome... 1 0
CFFCD174 Arachidonate 5-lipoxygenase Inhibitor Linazolast Family 1 1
CFFCD175 Aldose reductase Inhibitor Sorbinil Family 3 23
CFFCD176 Hemagglutinin Inhibitor Arbidol Family 1 4
CFFCD177 Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
CFFCD178 Arachidonate 5-lipoxygenase Inhibitor Lonapalene Family 1 31
CFFCD179 C-C chemokine receptor type 5 Ligand Vicriviroc Family 4 31
CFFCD180 Thromboxane A2 receptor Ligand Ifetroban Family 29 22
CFFCD181 Calcium-activated potassium channel subunit alpha-1 Ligand ICA... 14 14
CFFCD182 Retinoic acid receptor alpha Ligand LG100268 Family 2 33
CFFCD183 Muscarinic acetylcholine receptor M1 Ligand Sabcomeline Family 3 4
CFFCD184 23S rRNA Inhibitor Evernimicin Family 1 0
CFFCD185 Aldose reductase Inhibitor Zenarestat Family 1 2
CFFCD186 Prostaglandin G/H synthase 2 Inhibitor Rpr 200765a Family 9 125
CFFCD187 Adenosine receptor A1 Ligand CVT-124 Family 5 6
CFFCD188 Neuraminidase Inhibitor Peramivir Family 8 26
CFFCD189 Adenosine receptor A2a Ligand Atl-146e Family 33 94
CFFCD190 Thymidylate synthase Inhibitor Plevitrexed (r)-isomer Family 1 1
CFFCD191 DNA topoisomerase 2-beta Inhibitor TOP-53 Family 2 12
CFFCD192 Nonstructural protein 5b Inhibitor T-705 Family 1 0
CFFCD193 Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
CFFCD194 Lipase Inhibitor Cetilistat Family 1 13
CFFCD195 Multidrug resistance protein Inhibitor Tariquidar Family 3 60
CFFCD196 Endothelin-1 receptor Ligand Atrasentan Family 127 336
CFFCD197 Multidrug resistance protein Inhibitor Valspodar Family 1 1
CFFCD198 Type-2 angiotensin II receptor Ligand PS433540 Family 1 0
CFFCD199 Arachidonate 5-lipoxygenase Inhibitor Licofelone Family 2 6
CFFCD200 Muscarinic acetylcholine receptor M1 Ligand Talsaclidine Fumar... 1 0
CFFCD201 C-C chemokine receptor type 5 Ligand GW873140 Family 6 78
CFFCD202 Multidrug resistance-associated protein 1 Inhibitor Benzbromar... 2 16
CFFCD203 Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
CFFCD204 Adenosine receptor A2a Ligand KW-6002 Family 18 195
CFFCD205 Arachidonate 5-lipoxygenase Inhibitor ABT-761 Family 1 3
CFFCD206 Thromboxane A2 receptor Ligand Bibv 308 Family 14 40
CFFCD207 Thromboxane A2 receptor Ligand Ramatroban Family 13 49
CFFCD208 Dopamine reuptake Inhibitor Brasofensine Family 1 0
CFFCD209 Toll-like receptor 7 Ligand Isatoribine Family 1 2
CFFCD210 Cannabinoid receptor 1 Ligand Taranabant Family 20 30
CFFCD211 Muscarinic acetylcholine receptor M1 Ligand Xanomeline Tartrat... 1 0
CFFCD212 DNA topoisomerase 2-beta Inhibitor Salvicine Family 2 9
CFFCD213 Tubulin beta chain Inhibitor Tasidotin Family 1 1
CFFCD214 Melatonin receptor type 1A Ligand Agomelatine Family 12 164
CFFCD215 P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Family 10 18
CFFCD216 Acetyl-CoA acetyltransferase, mitochondrial Inhibitor Benoxapr... 1 76
CFFCD217 D(2) dopamine receptor Ligand Nomifensine Family 6 100
CFFCD218 Dopamine reuptake Inhibitor Amineptine Family 2 5
CFFCD219 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 2
CFFCD220 Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
CFFCD221 HER Inhibitor AC480 Family 4 67
CFFCD222 Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
CFFCD223 Epidermal growth factor receptor and Receptor tyrosine-protein... 16 89
CFFCD224 Epidermal growth factor receptor and Receptor tyrosine-protein... 1 0
CFFCD225 Vascular endothelial growth factor receptor 2 Ligand Ptk787/zk... 5 38
CFFCD226 Vascular endothelial growth factor receptor 2 Ligand CP-547632... 1 9
CFFCD227 Mast/stem cell growth factor receptor Kit and Vascular endothe... 1 4
CFFCD228 Macrophage colony-stimulating factor 1 and Vascular endothelia... 1 1
CFFCD229 Vascular endothelial growth factor receptor 2 Ligand Cediranib... 8 38
CFFCD230 Vascular endothelial growth factor receptor 2 Ligand BAY-57-93... 1 0
CFFCD231 Fibroblast growth factor receptor 3 Ligand BMS-582664 Family 2 23
CFFCD232 Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
CFFCD233 Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
CFFCD234 Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
CFFCD235 Dual specificity mitogen-activated protein kinase kinase Inhib... 5 13
CFFCD236 Insulin-like growth factor 1 receptor Ligand AEW-541 Family 12 140
CFFCD237 Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
CFFCD238 Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 25 40
CFFCD239 Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 67 130
CFFCD240 NAD-dependent protein deacetylase sirtuin-1 Inhibitor GSK18407... 1 0
CFFCD241 Oxytocin receptor Ligand GSK221149 Family 1 26
CFFCD242 Histamine H3 receptor Ligand GSK239512 Family 2 65
CFFCD243 cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 15 18
CFFCD244 Substance-P receptor Ligand GSK424887 Family 8 184
CFFCD245 Corticotropin-releasing factor receptor 1 Ligand GSK561679 Family 5 6
CFFCD246 Muscarinic acetylcholine receptor M1 Ligand GSK573719 Family 2 0
CFFCD247 D(3) dopamine receptor Ligand GSK618334 Family 10 21
CFFCD248 Beta-2 adrenergic receptor Ligand GW642444 Family 3 7
CFFCD249 Orexin receptor type 1 Ligand SB-649868 Family 7 3
CFFCD250 C-X-C chemokine receptor type 2 Ligand SB-656933 Family 3 7
CFFCD251 Glucocorticoid receptor Ligand GW685698X Family 2 1
CFFCD252 5-hydroxytryptamine receptor 6 Ligand SB-742457 Family 9 66
CFFCD253 Histamine H1 receptor and Histamine H3 receptor Ligand GSK8357... 2 2
CFFCD254 Motilin receptor Ligand GSK962040 Family 30 457
CFFCD255 Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 13 18
CFFCD256 Sodium channel Ligand GSK1014802 Family 4 92
CFFCD257 Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
CFFCD258 Dual specificity mitogen-activated protein kinase kinase Inhib... 1 0
CFFCD259 Integrase Inhibitor S-349572 Family 3 0
CFFCD260 Gastrin-releasing peptide receptor Ligand GSK1292263 Family 1 0
CFFCD261 Mu-type opioid receptor Ligand GSK1521498 Family 1 0
CFFCD262 Bcl-2-like protein 1 and Apoptosis regulator Bcl-2 Inhibitor A... 4 6
CFFCD263 Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
CFFCD264 Peroxisome proliferator-activated receptor alpha Ligand Alegli... 29 7
CFFCD265 Dipeptidyl peptidase 4 Inhibitor Alogliptin Family 6 25
CFFCD266 Angiopoietin-1 and Angiopoietin-2 Inhibitor Amg 386 Family 1 1
CFFCD267 Dual specificity mitogen-activated protein kinase kinase Inhib... 1 3
CFFCD268 NAD(P)H dehydrogenase [quinone] 1 Inhibitor Apaziquone Family 1 0
CFFCD269 Coagulation factor X Inhibitor Apixaban Family 34 52
CFFCD270 Atrial natriuretic peptide receptor 1 Ligand Ataciguat Family 7 45
CFFCD271 Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
CFFCD272 Cannabinoid receptor 1 Ligand AVE1625 Family 2 19
CFFCD273 Nicotinic acetylcholine receptor Ligand AZD0328 Family 11 97
CFFCD274 Prothrombin Inhibitor AZD0837 Family 1 0
CFFCD275 Aurora kinase B and Aurora kinase A Inhibitor AZD1152 Family 24 11
CFFCD276 Macrophage metalloelastase Inhibitor AZD1236 Family 1 0
CFFCD277 Cannabinoid receptor 1 Ligand AZD1940 Family 1 0
CFFCD278 Prostaglandin D2 receptor 2 Ligand AZD1981 Family 11 28
CFFCD279 Cannabinoid receptor 1 Ligand AZD2207 Family 18 48
CFFCD280 Gamma-aminobutyric acid B receptor Ligand AZD3355 Family 4 9
CFFCD281 Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor AZD40... 1 0
CFFCD282 C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
CFFCD283 Myeloperoxidase Inhibitor AZD5904 Family 1 2
CFFCD284 Prostaglandin D2 receptor 2 Ligand AZD5985 Family 1 0
CFFCD285 Dual specificity mitogen-activated protein kinase kinase Inhib... 2 0
CFFCD286 Gamma-aminobutyric acid A receptor Ligand AZD6280 Family 1 0
CFFCD287 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
CFFCD288 Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Family 26 90
CFFCD289 Serine/threonine-protein kinase mTOR Inhibitor AZD8055 Family 2 2
CFFCD290 Dual specificity mitogen-activated protein kinase kinase Inhib... 2 20
CFFCD291 DNA topoisomerase 1 Inhibitor Beta-lapachone Family 3 66
CFFCD292 B-lymphocyte antigen CD20 Inhibitor Bevacizumab+rituximab Family 1 5
CFFCD293 P2Y purinoceptor 12 Inhibitor Brilinta Family 1 1
CFFCD294 Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Family 3 16
CFFCD295 Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Family 2 9
CFFCD296 Cholesteryl ester transfer protein Inhibitor CP-800569 Family 5 81
CFFCD297 Cannabinoid receptor 1 Ligand CP-945598 Family 18 173
CFFCD298 Tumor necrosis factor Inhibitor Cytofab Family 1 10
CFFCD299 Tumor necrosis factor receptor superfamily member 5 Ligand Dac... 48 288
CFFCD300 Cholesteryl ester transfer protein Inhibitor Dalcetrapib Family 1 2
CFFCD301 Tumor necrosis factor receptor superfamily member 10A and Tumo... 6 34
CFFCD302 Alpha-1A adrenergic receptor Ligand Dutasteride & Tamsulosin F... 1 0
CFFCD303 Glucagon receptor Ligand Dwlip-gcgrrx Family 5 26
CFFCD304 Integrin alpha-4 Inhibitor Firategrast Family 3 93
CFFCD305 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 0
CFFCD306 Reverse transcriptase Inhibitor IDX899 Family 2 118
CFFCD307 Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family 3 130
CFFCD308 Sodium/glucose cotransporter 2 Inhibitor Isis-5glt2rx Family 1 8
CFFCD309 C-reactive protein Inhibitor ISIS-CRP Family 4 105
CFFCD310 Neuronal acetylcholine receptor subunit alpha-4 Ligand Isproni... 49 172
CFFCD311 Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
CFFCD312 Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
CFFCD313 5-hydroxytryptamine receptor Ligand Lu AA21004 Family 13 39
CFFCD314 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor MK-0... 3 32
CFFCD315 Gamma secretase Inhibitor MK-0752 Family 4 15
CFFCD316 Wee1-like protein kinase Inhibitor MK-1775 Family 1 0
CFFCD317 RAC-gamma serine/threonine-protein kinase Inhibitor MK-2206 Fa... 2 0
CFFCD318 Poly [ADP-ribose] polymerase 1 Inhibitor MK-4827 Family 8 43
CFFCD319 Aurora kinase B and Aurora kinase A Inhibitor MK-5108 Family 1 0
CFFCD320 Adenosine receptor A1 Ligand MK-7418 Family 21 116
CFFCD321 Hepatocyte growth factor receptor Ligand MK-8033 Family 19 42
CFFCD322 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 1 1
CFFCD323 NEDD8-activating enzyme E1 catalytic subunit Inhibitor MLN4924... 2 0
CFFCD324 Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
CFFCD325 Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 13 242
CFFCD326 B-lymphocyte antigen CD20 Inhibitor Ofatumumab Family 2 0
CFFCD327 Substance-P receptor Ligand Orvepitant Family 11 46
CFFCD328 Coagulation factor X Inhibitor Otamixaban Family 9 21
CFFCD329 Epidermal growth factor receptor and Receptor tyrosine-protein... 8 31
CFFCD330 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 2 2
CFFCD331 Coagulation factor X Inhibitor PD-348292 Family 7 0
CFFCD332 Metabotropic glutamate receptor 1 Ligand PF-1913539 Family 130 817
CFFCD333 D(3) dopamine receptor Ligand PF-217830 Family 21 7
CFFCD334 DNA damage-inducible transcript 4 protein Inhibitor PF-4523655... 1 0
CFFCD335 Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 1 16
CFFCD336 E3 ubiquitin-protein ligase Mdm2 Inhibitor R7112 Family 1 13
CFFCD337 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 2 1
CFFCD338 Glucokinase Inhibitor R7201 Family 22 105
CFFCD339 HIV protease Inhibitor Danoprevir Family 3 0
CFFCD340 Placenta growth factor Inhibitor R7334 Family 1 2
CFFCD341 Sodium/glucose cotransporter 2 Inhibitor Remogliflozin Etabona... 1 1
CFFCD342 Toll-like receptor 4 Ligand Resatorvid Family 2 3
CFFCD343 B-lymphocyte antigen CD20 Inhibitor Rituxan Immunology Family 10 17
CFFCD344 Extracellular calcium-sensing receptor Ligand Ronacaleret Family 2 9
CFFCD345 Peroxisome proliferator-activated receptor gamma Ligand Rosigl... 1 2
CFFCD346 Dipeptidyl peptidase 4 Inhibitor Saxagliptin Family 3 5
CFFCD347 Corticotropin-releasing factor receptor 1 Ligand SSR125543 Family 2 1
CFFCD348 Peptidoglycan synthase FtsI Inhibitor Sulopenem Family 2 0
CFFCD349 Dipeptidyl peptidase 4 Inhibitor TAK-100 Family 5 7
CFFCD350 Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
CFFCD351 Gonadotropin-releasing hormone receptor Ligand TAK-385 Family 2 0
CFFCD352 Coagulation factor X Inhibitor TAK-442 Family 3 12
CFFCD353 KiSS-1 receptor Ligand TAK-683 Family 2 5
CFFCD354 Hepatocyte growth factor receptor Ligand TAK-701 Family 3 4
CFFCD355 Aurora kinase B Inhibitor TAK-901 Family 1 0
CFFCD356 Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
CFFCD357 cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor UK-3690... 35 10
CFFCD358 Endothelin-1 receptor Ligand Zibotentan Family 1 0
CFFCD359 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 159
CFFCD360 Muscarinic acetylcholine receptor Ligand Aclidinium Bromide Fa... 8 2
CFFCD361 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 7
CFFCD362 Pigment epithelium-derived factor Inhibitor Adpedr Family 2 112
CFFCD363 Protein kinase C Inhibitor AEB07 Family 1 0
CFFCD364 Thrombopoietin receptor Ligand AKR-501 Family 2 8
CFFCD365 Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
CFFCD366 Urokinase-type plasminogen activator Inhibitor Amediplase Family 1 28
CFFCD367 Beta-3 adrenergic receptor Ligand Amibegron Family 8 46
CFFCD368 D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
CFFCD369 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Apre... 1 4
CFFCD370 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
CFFCD371 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
CFFCD372 Kappa-type opioid receptor Ligand Asimadoline Family 14 54
CFFCD373 Progesterone receptor Ligand Asoprisnil Family 1 0
CFFCD374 Signal transducer and activator of transcription 3 Inhibitor A... 1 1
CFFCD375 D(3) dopamine receptor Ligand AVE-5997EF Family 1 5
CFFCD376 Potassium voltage-gated channel subfamily A member 5 Ligand Az... 1 3
CFFCD377 Glutamate receptor AMPA subtype Ligand Becampanel Family 2 20
CFFCD378 Cyclooxygenase Inhibitor Benzydamine Family 1 8
CFFCD379 C-C chemokine receptor type 3 Ligand Bertilimumab?? Family 3 9
CFFCD380 Adenosine receptor A2a Ligand BG-9928 Family 8 11
CFFCD381 Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 9 17
CFFCD382 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3 27
CFFCD383 Adenosine receptor A2a Ligand BIIB014 Family 26 92
CFFCD384 Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Family 9 46
CFFCD385 5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 3 67
CFFCD386 Sodium channel Ligand Carisbamate Family 1 0
CFFCD387 Cannabinoid receptor 1 Ligand Cbd Cannabis Derivative Family 1 3
CFFCD388 Integrin alpha-4 Inhibitor CDP323 Family 8 17
CFFCD389 D-alanyl-D-alanine carboxypeptidase Inhibitor Ceftobiprole Family 1 0
CFFCD390 23S rRNA Inhibitor Cethromycin Family 1 0
CFFCD391 Adenosine receptor A3 Ligand CF101 Family 24 560
CFFCD392 Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 3
CFFCD393 cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
CFFCD394 Calcitonin gene-related peptide 1 Inhibitor Cizolirtine Family 3 15
CFFCD395 Arachidonate 5-lipoxygenase Inhibitor CJ-13610 Family 2 6
CFFCD396 NMDA receptor Ligand CNS-5161 Family 3 18
CFFCD397 Corticotropin-releasing factor receptor 1 Ligand Cp-316,311 Fa... 5 74
CFFCD398 Corticotropin-releasing factor receptor 2 Ligand Crf-r2 Antago... 1 0
CFFCD399 Neuromedin-K receptor and Substance-K receptor Ligand CS-003 F... 2 14
CFFCD400 Glutamate receptor AMPA subtype Ligand CX-516 Family 9 24
CFFCD401 Substance-P receptor Ligand DA-5018 Family 14 73
CFFCD402 Reverse transcriptase Inhibitor Dapivirine Family 5 72
CFFCD403 5-hydroxytryptamine receptor 3A Ligand DDP-225 Family 1 7
CFFCD404 Adenosine receptor A2a Ligand Dexefaroxan Family 11 46
CFFCD405 Translocator protein Inhibitor Dextofisopam Family 3 250
CFFCD406 P2Y purinoceptor 2 Inhibitor Diquafosol Family 2 44
CFFCD407 Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
CFFCD408 Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89
CFFCD409 Potassium voltage-gated channel subfamily A member 5 Ligand Dr... 1 2
CFFCD410 NMDA receptor Ligand D-serine Family 1 7
CFFCD411 Vascular endothelial growth factor receptor 2 Ligand E 7080 Fa... 7 17
CFFCD412 Tubulin Inhibitor E 7974 Family 1 7
CFFCD413 Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
CFFCD414 Sigma non-opioid intracellular receptor 1 Ligand E-5842 Family 1 0
CFFCD415 NMDA receptor Ligand EAA-090 Family 1 2
CFFCD416 Sodium channel Ligand Eslicarbazepine Acetate Family 3 1
CFFCD417 Thrombopoietin receptor Ligand Eltrombopag Family 1 1
CFFCD418 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 23
CFFCD419 Translocator protein Inhibitor Emapunil Family 7 89
CFFCD420 Growth hormone receptor Ligand EP-51216 Family 34 390
CFFCD421 Substance-P receptor Ligand Ezlopitant Family 10 207
CFFCD422 Glutamate receptor 1 Ligand Farampator Family 1 1
CFFCD423 Interferon gamma Inhibitor Fumaric Acid Family 3 10
CFFCD424 DNA Binder Glufosfamide Family 1 0
CFFCD425 5-hydroxytryptamine receptor 2A and D(1B) dopamine receptor Li... 1 1
CFFCD426 Glutamate carboxypeptidase 2 Inhibitor GPI-16072 Family 7 8
CFFCD427 Gp29 Inhibitor GRN163 Family 1 0
CFFCD428 Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 7 61
CFFCD429 Beta-2 adrenergic receptor Ligand GSK642444 Family 4 10
CFFCD430 Prostaglandin G/H synthase 2 Inhibitor GSK-644784 Family 2 0
CFFCD431 Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 0
CFFCD432 Prostaglandin G/H synthase 2 Inhibitor GW-406381 Family 3 10
CFFCD433 Beta-3 adrenergic receptor Ligand GW-427353 Family 3 5
CFFCD434 Adenosine receptor A2a Ligand GW-493838 Family 1 0
CFFCD435 Corticotropin-releasing factor receptor 1 Ligand GW876008 Family 3 30
CFFCD436 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 1 0
CFFCD437 Interleukin-1 beta and Interleukin-6 Inhibitor Ibudilast Family 2 11
CFFCD438 Alpha-2 adrenergic receptor Ligand Idazoxan Family 6 26
CFFCD439 Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
CFFCD440 Interleukin-1 Inhibitor K-832 Family 1 0
CFFCD441 5-hydroxytryptamine receptor 3A Ligand KB-6806 Family 12 11
CFFCD442 Voltage-gated sodium channel Ligand Lacosamide Family 1 10
CFFCD443 D(2) dopamine receptor Ligand Lamectacin Family 1 0
CFFCD444 C-X-C motif chemokine 2 Inhibitor Laquinamod Family 2 2
CFFCD445 D(1B) dopamine receptor Ligand LE-300 Family 65 452
CFFCD446 5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38
CFFCD447 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 1 0
CFFCD448 NMDA receptor Ligand Magnesium Family 2 1 1
CFFCD449 Apoptosis regulator Bcl-2 Inhibitor MCI-186 Family 2 25
CFFCD450 C-C chemokine receptor type 2 Ligand MLN1202 Family 1 0
CFFCD451 5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
CFFCD452 Adenosine receptor A2a Ligand MRE-0094 Family 10 108
CFFCD453 Sigma non-opioid intracellular receptor 1 Ligand MS-377 Family 1 21
CFFCD454 D(2) dopamine receptor Ligand N-0923 Family 6 41
CFFCD455 NMDA receptor Ligand Neramexane Family 1 0
CFFCD456 Sodium-dependent noradrenaline transporter Inhibitor Neri Iv F... 6 58
CFFCD457 Glutamate receptor AMPA subtype Ligand Ns 1209 Family 1 0
CFFCD458 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor ONO-... 2 0
CFFCD459 Glucocorticoid receptor Ligand Org 34517/34850 Family 2 4
CFFCD460 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 2 18
CFFCD461 Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
CFFCD462 D(2) dopamine receptor Ligand Pardoprunox Family 4 81
CFFCD463 D(2) dopamine receptor and D(3) dopamine receptor Ligand PD-15... 2 9
CFFCD464 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 14 234
CFFCD465 D(4) dopamine receptor Ligand PD-165167 Family 2 96
CFFCD466 Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 64 96
CFFCD467 Carbonic anhydrase and Gamma-aminobutyric acid receptor Ligand... 1 0
CFFCD468 5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
CFFCD469 Voltage-dependent L-type calcium channel Ligand Pinaverium Bro... 1 1
CFFCD470 Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
CFFCD471 5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 7 28
CFFCD472 5-hydroxytryptamine receptor 4 Ligand Pumosetrag Family 1 0
CFFCD473 Beta-2 adrenergic receptor Ligand QVA-149 Family 1 0
CFFCD474 Substance-P receptor Ligand R 673 Family 2 127
CFFCD475 Tyrosine-protein kinase SYK Inhibitor R-788 Family 1 0
CFFCD476 Cytochrome P450 26A1 Inhibitor Rambazole Family 7 77
CFFCD477 C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 5 30
CFFCD478 Transient receptor potential cation channel subfamily V member... 29 18
CFFCD479 Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 0
CFFCD480 Glutamate receptor ionotropic, NMDA 2B Ligand RGH-896 Family 2 1
CFFCD481 Rho-associated protein kinase 1 Inhibitor Rho-kinase Inhibitor... 6 39
CFFCD482 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 1 42
CFFCD483 D(2) dopamine receptor Ligand Rotigotine Patch Family 1 2
CFFCD484 Sodium-dependent dopamine transporter Inhibitor RTI-336 Family 21 61
CFFCD485 5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 9 115
CFFCD486 Vasopressin V2 receptor Ligand Satavaptan Family 3 0
CFFCD487 C-X-C chemokine receptor type 2 Ligand SB-265610 Family 1 1
CFFCD488 D(3) dopamine receptor Ligand SB-277011 Family 13 178
CFFCD489 Synaptic vesicle glycoprotein 2A Inhibitor Seletracetam Family 1 0
CFFCD490 Beta-2 adrenergic receptor and D(2) dopamine receptor Ligand S... 1 0
CFFCD491 Neutrophil elastase Inhibitor Sivelestat Sodium Hydrate Family 2 2
CFFCD492 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 11 49
CFFCD493 5-hydroxytryptamine receptor 1A and Cannabinoid receptor 1 Lig... 11 39
CFFCD494 Adenosine receptor A1 Ligand SLV320 Family 6 79
CFFCD495 DNA topoisomerase 2-beta Inhibitor SNS-595 Family 1 0
CFFCD496 Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
CFFCD497 D(4) dopamine receptor Ligand SPI-376 Family 7 84
CFFCD498 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
CFFCD499 Sigma non-opioid intracellular receptor 1 Ligand SSR-125047 Fa... 1 2
CFFCD500 Vasopressin V1b receptor Ligand SSR149415 Family 7 12
showing 1 to 500 of 863. <<First <Prev Page 1 Next> Last>>

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

20947 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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