CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

showing 1 to 218 of 218. <<First <Prev Page 1 Next> Last>>
show families with seed and member seed only

Browsing Family of Functional Category "Clinical Trial Drug"


IDNameSeedsMembers
CFFCD1 Tyrosine-protein phosphatase non-receptor type 6 Ligand Sodium... 1 0
CFFCD14 Platelet-activating factor acetylhydrolase Inhibitor Gsk 65903... 1 0
CFFCD15 Mitogen-activated protein kinase 12 Inhibitor SB681323 Family 1 0
CFFCD22 Heat shock protein HSP 90-alpha Inhibitor Alvespimycin Family 7 0
CFFCD23 Arachidonate 5-lipoxygenase-activating protein Inhibitor AM803... 1 0
CFFCD26 Leukotriene B4 receptor 1 Ligand Amelubant Family 1 0
CFFCD29 Transient receptor potential cation channel subfamily V member... 2 0
CFFCD30 Tumor necrosis factor Inhibitor AN0128 Family 1 0
CFFCD39 Aurora kinase B and Aurora kinase A Inhibitor AT9283 Family 2 0
CFFCD50 Mitogen-activated protein kinase 8 Inhibitor CC-401 Family 1 0
CFFCD54 Neurotensin receptor type 1 Ligand CGX-1160 Family 1 0
CFFCD57 Macrophage migration inhibitory factor Inhibitor COR100140 Family 1 0
CFFCD60 Serine/threonine-protein kinase PLK1 Inhibitor CYC-800 Family 1 0
CFFCD77 Centromere-associated protein E Inhibitor GSK-923295 Family 1 0
CFFCD82 Microsomal triglyceride transfer protein large subunit Inhibit... 1 0
CFFCD84 C-C chemokine receptor type 2 Ligand INCB3284 Family 1 0
CFFCD86 Glucosylceramidase Inhibitor Isofagomine Tartrate Family 1 0
CFFCD92 Serine/threonine-protein kinase PLK1 Inhibitor LC-445 Family 2 0
CFFCD93 Cholecystokinin receptor type A Ligand Lintitript Family 1 0
CFFCD102 Metabotropic glutamate receptor 3 Ligand LY404039 Family 4 0
CFFCD107 Motilin receptor Ligand Mitemcinal Family 5 0
CFFCD109 Hepatocyte growth factor receptor and Mast/stem cell growth fa... 1 0
CFFCD111 C-X-C chemokine receptor type 4 Ligand MSX-122 Family 1 0
CFFCD112 Corticotropin-releasing factor receptor 1 Ligand NBI-34041 Family 1 0
CFFCD113 Corticotropin-releasing factor receptor 1 Ligand NBI-37582 Family 2 0
CFFCD116 Phosphodiesterase and Thromboxane-A synthase Inhibitor NM-702 ... 1 0
CFFCD124 Nuclear factor NF-kappa-B p100 subunit Inhibitor PG-490-88 Family 3 0
CFFCD127 Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor P... 1 0
CFFCD128 Glucokinase Inhibitor PSN-101 Family 1 0
CFFCD137 B-lymphocyte antigen CD19 Inhibitor SAR3419 Family 1 0
CFFCD143 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD146 Substance-K receptor Ligand Sr 144190 Family 2 0
CFFCD150 Heat shock protein HSP 90-alpha Inhibitor STA-9090 Family 2 0
CFFCD152 C-X-C chemokine receptor type 3 Ligand T487 Family 1 0
CFFCD153 Transcription factor AP-1 Inhibitor T-5224 Family 1 0
CFFCD162 Coagulation factor IX Inhibitor TTP889 Family 1 0
CFFCD168 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD169 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD172 Serine/threonine-protein kinase PLK1 Inhibitor Zk-thiazolidino... 1 0
CFFCD173 Muscarinic acetylcholine receptor M1 Ligand Talsaclidine Isome... 1 0
CFFCD184 23S rRNA Inhibitor Evernimicin Family 1 0
CFFCD192 Nonstructural protein 5b Inhibitor T-705 Family 1 0
CFFCD198 Type-2 angiotensin II receptor Ligand PS433540 Family 1 0
CFFCD200 Muscarinic acetylcholine receptor M1 Ligand Talsaclidine Fumar... 1 0
CFFCD208 Dopamine reuptake Inhibitor Brasofensine Family 1 0
CFFCD211 Muscarinic acetylcholine receptor M1 Ligand Xanomeline Tartrat... 1 0
CFFCD224 Epidermal growth factor receptor and Receptor tyrosine-protein... 1 0
CFFCD230 Vascular endothelial growth factor receptor 2 Ligand BAY-57-93... 1 0
CFFCD234 Angiopoietin-1 receptor and Vascular endothelial growth factor... 1 0
CFFCD240 NAD-dependent protein deacetylase sirtuin-1 Inhibitor GSK18407... 1 0
CFFCD246 Muscarinic acetylcholine receptor M1 Ligand GSK573719 Family 2 0
CFFCD258 Dual specificity mitogen-activated protein kinase kinase Inhib... 1 0
CFFCD259 Integrase Inhibitor S-349572 Family 3 0
CFFCD260 Gastrin-releasing peptide receptor Ligand GSK1292263 Family 1 0
CFFCD261 Mu-type opioid receptor Ligand GSK1521498 Family 1 0
CFFCD268 NAD(P)H dehydrogenase [quinone] 1 Inhibitor Apaziquone Family 1 0
CFFCD274 Prothrombin Inhibitor AZD0837 Family 1 0
CFFCD276 Macrophage metalloelastase Inhibitor AZD1236 Family 1 0
CFFCD277 Cannabinoid receptor 1 Ligand AZD1940 Family 1 0
CFFCD281 Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor AZD40... 1 0
CFFCD284 Prostaglandin D2 receptor 2 Ligand AZD5985 Family 1 0
CFFCD285 Dual specificity mitogen-activated protein kinase kinase Inhib... 2 0
CFFCD286 Gamma-aminobutyric acid A receptor Ligand AZD6280 Family 1 0
CFFCD302 Alpha-1A adrenergic receptor Ligand Dutasteride & Tamsulosin F... 1 0
CFFCD305 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 0
CFFCD316 Wee1-like protein kinase Inhibitor MK-1775 Family 1 0
CFFCD317 RAC-gamma serine/threonine-protein kinase Inhibitor MK-2206 Fa... 2 0
CFFCD319 Aurora kinase B and Aurora kinase A Inhibitor MK-5108 Family 1 0
CFFCD323 NEDD8-activating enzyme E1 catalytic subunit Inhibitor MLN4924... 2 0
CFFCD326 B-lymphocyte antigen CD20 Inhibitor Ofatumumab Family 2 0
CFFCD331 Coagulation factor X Inhibitor PD-348292 Family 7 0
CFFCD334 DNA damage-inducible transcript 4 protein Inhibitor PF-4523655... 1 0
CFFCD339 HIV protease Inhibitor Danoprevir Family 3 0
CFFCD348 Peptidoglycan synthase FtsI Inhibitor Sulopenem Family 2 0
CFFCD351 Gonadotropin-releasing hormone receptor Ligand TAK-385 Family 2 0
CFFCD355 Aurora kinase B Inhibitor TAK-901 Family 1 0
CFFCD358 Endothelin-1 receptor Ligand Zibotentan Family 1 0
CFFCD363 Protein kinase C Inhibitor AEB07 Family 1 0
CFFCD373 Progesterone receptor Ligand Asoprisnil Family 1 0
CFFCD386 Sodium channel Ligand Carisbamate Family 1 0
CFFCD389 D-alanyl-D-alanine carboxypeptidase Inhibitor Ceftobiprole Family 1 0
CFFCD390 23S rRNA Inhibitor Cethromycin Family 1 0
CFFCD398 Corticotropin-releasing factor receptor 2 Ligand Crf-r2 Antago... 1 0
CFFCD414 Sigma non-opioid intracellular receptor 1 Ligand E-5842 Family 1 0
CFFCD424 DNA Binder Glufosfamide Family 1 0
CFFCD427 Gp29 Inhibitor GRN163 Family 1 0
CFFCD430 Prostaglandin G/H synthase 2 Inhibitor GSK-644784 Family 2 0
CFFCD431 Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 0
CFFCD434 Adenosine receptor A2a Ligand GW-493838 Family 1 0
CFFCD436 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 1 0
CFFCD440 Interleukin-1 Inhibitor K-832 Family 1 0
CFFCD443 D(2) dopamine receptor Ligand Lamectacin Family 1 0
CFFCD447 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 1 0
CFFCD450 C-C chemokine receptor type 2 Ligand MLN1202 Family 1 0
CFFCD455 NMDA receptor Ligand Neramexane Family 1 0
CFFCD457 Glutamate receptor AMPA subtype Ligand Ns 1209 Family 1 0
CFFCD458 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor ONO-... 2 0
CFFCD467 Carbonic anhydrase and Gamma-aminobutyric acid receptor Ligand... 1 0
CFFCD472 5-hydroxytryptamine receptor 4 Ligand Pumosetrag Family 1 0
CFFCD473 Beta-2 adrenergic receptor Ligand QVA-149 Family 1 0
CFFCD475 Tyrosine-protein kinase SYK Inhibitor R-788 Family 1 0
CFFCD479 Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 0
CFFCD486 Vasopressin V2 receptor Ligand Satavaptan Family 3 0
CFFCD489 Synaptic vesicle glycoprotein 2A Inhibitor Seletracetam Family 1 0
CFFCD490 Beta-2 adrenergic receptor and D(2) dopamine receptor Ligand S... 1 0
CFFCD495 DNA topoisomerase 2-beta Inhibitor SNS-595 Family 1 0
CFFCD498 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 0
CFFCD503 D(2) dopamine receptor Ligand Sumanirole Family 1 0
CFFCD513 Interleukin-12 subunit alpha and Interleukin-23 subunit alpha ... 1 0
CFFCD516 D(2) dopamine receptor Ligand Y-931 Family 1 0
CFFCD517 5-hydroxytryptamine receptor 2A and D(1B) dopamine receptor Li... 1 0
CFFCD520 Aurora kinase A Inhibitor ENMD-2076 Family 1 0
CFFCD523 Serine/threonine-protein kinase Chk1 Inhibitor PF-477736 Family 1 0
CFFCD528 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD534 Serine/threonine-protein kinase mTOR Inhibitor OSI-027 Family 1 0
CFFCD541 Glutamate receptor ionotropic, NMDA 2B Ligand Besonprodil Family 1 0
CFFCD542 Envelope glycoprotein gp120 Inhibitor BMS-488043 Family 1 0
CFFCD546 Heat shock protein 90, putative Inhibitor Nvp-auy922 Family 1 0
CFFCD552 Serine/threonine-protein kinase receptor R3 Ligand ACE-041 Family 1 0
CFFCD556 HIV protease Inhibitor Bms 650032 Family 1 0
CFFCD558 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 1 0
CFFCD565 HIV protease Inhibitor GS-9256 Family 2 0
CFFCD572 Opioid receptor Ligand S-297995 Family 1 0
CFFCD573 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 1 0
CFFCD576 HIV protease Inhibitor TMC435 Family 2 0
CFFCD577 Neuropeptide Y receptor type 5 Ligand Velneperit Family 1 0
CFFCD578 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 1 0
CFFCD579 Methionine aminopeptidase 2 Inhibitor ZGN-433 Family 1 0
CFFCD583 CK-2017357 family 1 0
CFFCD584 Gtx-024 family 5 0
CFFCD589 BG-12 family 1 0
CFFCD591 Baricitinib family 1 0
CFFCD592 LX2931 family 1 0
CFFCD594 Flupirtine family 1 0
CFFCD595 Solute carrier family 22 member 12 Inhibitor Lesinurad Family 1 0
CFFCD596 MBX-102 family 1 0
CFFCD598 Aliskiren/valsartan family 1 0
CFFCD600 TS-011 family 1 0
CFFCD607 MTR105 family 1 0
CFFCD611 M118 family 1 0
CFFCD616 LY2484595 family 1 0
CFFCD618 K201 family 1 0
CFFCD619 E5555 family 1 0
CFFCD620 Elinogrel family 1 0
CFFCD621 Neprilysin Inhibitor LCZ696 Family 1 0
CFFCD628 Selexipag family 1 0
CFFCD633 BMS-708163 family 1 0
CFFCD636 ST-101 family 1 0
CFFCD637 AZD4694 family 1 0
CFFCD638 T-817MA family 1 0
CFFCD644 Histamine family 1 0
CFFCD645 Maraciclatide family 2 0
CFFCD651 EC0489 family 3 0
CFFCD652 GL-0817 family 1 0
CFFCD653 TAS-102 family 1 0
CFFCD667 Hepatocyte growth factor receptor Ligand EMD-1214063 Family 1 0
CFFCD671 Gamma secretase Inhibitor PF-03084014 Family 1 0
CFFCD673 Poly [ADP-ribose] polymerase 1 Inhibitor BMN-673 Family 1 0
CFFCD677 Palifosfamide family 1 0
CFFCD678 Oprozomib family 2 0
CFFCD679 TH-302 family 1 0
CFFCD682 Elesclomol family 1 0
CFFCD684 Second-generation proteasome and Proteasome Inhibitor MLN9708 ... 1 0
CFFCD694 Indium-111 family 1 0
CFFCD695 EZN-2208 family 2 0
CFFCD696 NPI-0052 family 1 0
CFFCD701 Transient receptor potential cation channel subfamily M member... 1 0
CFFCD705 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD708 Obatoclax family 1 0
CFFCD714 TL-32711 family 1 0
CFFCD716 Dual specificity mitogen-activated protein kinase kinase Inhib... 1 0
CFFCD717 Samarium SM-153 Lexidronam family 1 0
CFFCD719 RAC-gamma serine/threonine-protein kinase and Serine/threonine... 1 0
CFFCD725 ARN-509 family 1 0
CFFCD726 PR104 family 1 0
CFFCD729 Efatutazone family 2 0
CFFCD731 HepB Inhibitor MB07133 Family 1 0
CFFCD732 Poly-iclc family 1 0
CFFCD736 Tesetaxel family 1 0
CFFCD739 Sr 16234 family 1 0
CFFCD742 Treosulfan family 1 0
CFFCD745 Plinabulin family 1 0
CFFCD748 Saridegib family 1 0
CFFCD749 Fibroblast growth factor receptor 1 Ligand AZD4547 Family 1 0
CFFCD753 Imexon family 1 0
CFFCD756 ARX-02 family 2 0
CFFCD759 Litronesib family 1 0
CFFCD764 E7850 family 1 0
CFFCD766 Sagopilone family 1 0
CFFCD770 Dimesna family 1 0
CFFCD772 Canfosfamide family 1 0
CFFCD774 PF-03715455 family 1 0
CFFCD778 Sodium/glucose cotransporter 2 Inhibitor ASP1941 Family 1 0
CFFCD780 Emricasan family 1 0
CFFCD793 GS-7340 family 2 0
CFFCD794 KP-1461 family 1 0
CFFCD795 Lersivirine family 1 0
CFFCD796 MK-1439 family 1 0
CFFCD797 VRX806 family 1 0
CFFCD799 Neboglamine family 1 0
CFFCD804 OPC-34712 family 1 0
CFFCD810 Metabotropic glutamate receptor 5 Ligand AFQ056 Family 1 0
CFFCD811 AM-831 family 1 0
CFFCD818 Azole antifungal Inhibitor Isavuconazole Family 1 0
CFFCD819 ASP1585 family 1 0
CFFCD821 Dipeptidyl peptidase 4 Inhibitor Kombiglyze Xr/komboglyze Fdc ... 1 0
CFFCD830 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
CFFCD836 Poly [ADP-ribose] polymerase 1 Inhibitor E7016 Family 1 0
CFFCD841 Oxytocin Inhibitor Retosiban Family 3 0
CFFCD843 8-aminoquinoline Inhibitor Tafenoquine Family 1 0
CFFCD844 Beta-2 adrenergic receptor and Glucocorticoid receptor Ligand ... 1 0
CFFCD849 Integrin Inhibitor AS101 Family 1 0
CFFCD850 Leo 80185 family 1 0
CFFCD851 PH-10 family 1 0
CFFCD852 SAR97276 family 1 0
CFFCD858 MK-7655 family 1 0
CFFCD859 MK-8228 family 1 0
CFFCD860 MK-08887A family 1 0
showing 1 to 218 of 218. <<First <Prev Page 1 Next> Last>>

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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