CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

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Browsing Family of Functional Category "Investigative Drug"


IDNameSeedsMembers
CFFID1 Gamma-aminobutyric acid A receptor Ligand Gaba Family 2 8
CFFID2 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 37 57
CFFID3 Cholecystokinin receptor type A Ligand A-71378 Family 77 23
CFFID4 Hepatitis C Virus RNA-dependent RNA Polymerase Inhibitor A-837... 1 0
CFFID5 Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 3 21
CFFID6 Hepatitis C Virus RNA-dependent RNA Polymerase Inhibitor AG-02... 1 0
CFFID7 Platelet activating factor, putative Inhibitor Web 2086 Family 2 34
CFFID8 Nociceptin receptor Ligand J-113397 Family 3 14
CFFID9 Neuropeptide Y receptor type 1 Ligand BIBO3304 Family 4 69
CFFID10 4-hydroxyphenylpyruvate dioxygenase Inhibitor BMS-433771 Family 1 2
CFFID11 Aldose reductase Inhibitor Tingenone Family 2 9
CFFID12 Nicotinic acetylcholine receptor Ligand Dianicline Family 6 13
CFFID13 72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
CFFID14 Gamma-aminobutyric acid uptake Inhibitor Nnc 711 Family 3 7
CFFID15 5-hydroxytryptamine receptor 2A Ligand N-(1-(1-phenylethyl)pip... 22 207
CFFID16 5-hydroxytryptamine receptor 2A Ligand Fananserin Family 13 49
CFFID17 Neuropeptide Y receptor type 1 Ligand GI-264879A Family 1 0
CFFID18 Glutamate receptor AMPA subtype Ligand GYKI-47261 Family 1 1
CFFID19 DNA topoisomerase Inhibitor Ahma Family 1 0
CFFID20 Platelet activating factor, putative Inhibitor Pinusolide Family 1 39
CFFID21 ATP-sensitive inward rectifier potassium channel 11 Ligand Ipt... 1 5
CFFID22 Mitogen-activated protein kinase 1 and Mitogen-activated prote... 2 1
CFFID23 Heat shock protein 90, putative Inhibitor Radicicol Family 3 42
CFFID24 Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Family 6 29
CFFID25 Neuropeptide Y receptor type 1 Ligand PD-160170 Family 1 11
CFFID26 Gastrin/cholecystokinin type B receptor Ligand PD136450 Family 53 117
CFFID27 Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
CFFID28 D(3) dopamine receptor Ligand RGH-1756 Family 2 2
CFFID29 Melanocortin receptor 4 Ligand Ro-27-3225 Family 6 52
CFFID30 C-C chemokine receptor type 2 and C-C motif chemokine 2 Ligand... 3 52
CFFID31 D(2) dopamine receptor and D(3) dopamine receptor Ligand S3250... 3 5
CFFID32 Aldose reductase Inhibitor Alrestatin Family 2 11
CFFID33 Substance-K receptor Ligand SLV-332 Family 1 1
CFFID34 D(4) dopamine receptor Ligand Sonepiprazole Family 2 6
CFFID35 Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
CFFID36 Potassium voltage-gated channel subfamily A member 5 Ligand S-... 34 206
CFFID37 Progesterone receptor Ligand Tanaproget Family 4 6
CFFID38 C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
CFFID39 C-C chemokine receptor type 3 Ligand YM-355179 Family 1 1
CFFID40 Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 1 0
CFFID41 Delta-type opioid receptor Ligand Sb 227122 Family 7 5
CFFID42 Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 2 24
CFFID43 Metabotropic glutamate receptor 5 Ligand LY467711 Family 1 0
CFFID44 Metabotropic glutamate receptor 5 Ligand LY525327 Family 1 0
CFFID45 Heat shock protein 90, putative Inhibitor CCT-018159 Family 1 1
CFFID46 Histone deacetylase 1 Inhibitor Chlamydocin Family 2 1
CFFID47 Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
CFFID48 Histone deacetylase 1 and Histone deacetylase 2 Inhibitor Depu... 2 0
CFFID49 Histone deacetylase 1 Inhibitor Hc-toxin Family 2 3
CFFID50 5-hydroxytryptamine receptor 2A Ligand RP-68303 Family 7 44
CFFID51 Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-4-isobutyl-ben... 4 43
CFFID52 Metabotropic glutamate receptor 5 Ligand Mcn3377 Family 1 12
CFFID53 Dipeptidyl peptidase 4 Inhibitor Nvp-dpp728 Family 11 42
CFFID54 C-C chemokine receptor type 5 Ligand Sch 351125 Family 6 29
CFFID55 C-C chemokine receptor type 5 Ligand Tak-220 Family 8 56
CFFID56 Heat shock protein 90, putative and Heat shock protein HSP 90-... 2 0
CFFID57 5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
CFFID58 72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
CFFID59 72 kDa type IV collagenase Inhibitor Metastat Family 1 0
CFFID60 Lethal factor Inhibitor GM6001 Family 50 435
CFFID61 XL-888 family 16 85
CFFID62 PF-4217903 family 14 65
CFFID63 PF-3758309 family 1 8
CFFID64 Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
CFFID65 Flovagatran family 12 546
CFFID66 Bis(5'-adenosyl)-triphosphatase Inhibitor Fructose Family 3 45
CFFID67 Granotapide family 1 0
CFFID68 Eprotirome family 11 50
CFFID69 PF-4136309 family 16 27
CFFID70 SPD-556 family 1 7
CFFID71 WAY-162545 family 2 4
CFFID72 6-phosphogluconate dehydrogenase, decarboxylating Inhibitor (2... 1 0
CFFID73 Metabotropic glutamate receptor 2 Ligand (2r,4r)-4-aminopyrrol... 1 2
CFFID74 Ornithine decarboxylase Inhibitor (2r,5r)-delta-methyl-alpha-a... 1 0
CFFID75 Gamma-aminobutyric acid uptake Inhibitor (r)-nipecotic Acid Fa... 4 2
CFFID76 5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
CFFID77 5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CFFID78 Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
CFFID79 Aminopeptidase N Inhibitor [(125)i] RB129 Family 11 204
CFFID80 5-hydroxytryptamine receptor 6 Ligand [125i]sb-258585 Family 1 0
CFFID81 Cyclin-dependent kinase 1 Inhibitor 10z-hymenialdisine Family 3 3
CFFID82 Peroxisome proliferator-activated receptor gamma Ligand 15-deo... 1 2
CFFID83 Peroxisome proliferator-activated receptor gamma Ligand (9z,11... 3 94
CFFID84 Heat shock protein 90, putative Inhibitor 17-allylamino-17-dem... 1 0
CFFID85 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 1 9
CFFID86 Arachidonate 5-lipoxygenase Inhibitor 1-furan-2-yl-3-pyridin-2... 1 3
CFFID87 Matrix protein 2 Inhibitor 2-(1-adamantyl) Piperidine Family 1 0
CFFID88 Matrix protein 2 Inhibitor 2-(1-adamantyl)-2-methyl-pyrrolidin... 3 0
CFFID89 Matrix protein 2 Inhibitor 2-(2-adamantyl) Piperidine Family 2 0
CFFID90 Gp29 Inhibitor 2,3,7-trichloro-5-nitroquinoxaline (tnqx) Family 1 1
CFFID91 DNA topoisomerase 1 Inhibitor 2,3-dimethoxybenzo[i]phenanthrid... 1 0
CFFID92 Glutathione reductase, mitochondrial Inhibitor 2,4,6 Trinitrob... 1 0
CFFID93 Thymidine phosphorylase Inhibitor 2'-aminoimidazolylmethylurac... 1 1
CFFID94 Isocitrate lyase Inhibitor 3-bromopyruvate Family 1 0
CFFID95 Alanine racemase Inhibitor 3-fluorovinylglycine Family 1 0
CFFID96 Kynureninase Inhibitor 3-methoxydesaminokynurenine Family 1 1
CFFID97 Isocitrate lyase Inhibitor 3-nitropropionate Family 1 1
CFFID98 Reverse transcriptase Inhibitor 3'thiacytidine Family 4 29
CFFID99 cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 8 55
CFFID100 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 1 0
CFFID101 Prothrombin and Urokinase-type plasminogen activator Inhibitor... 3 11
CFFID102 Dihydroorotase, putative Inhibitor 5-amino Orotate Family 2 4
CFFID103 6-phosphogluconate dehydrogenase, decarboxylating Inhibitor 5-... 2 7
CFFID104 Dihydroorotase, putative and Dihydroorotate dehydrogenase Inhi... 1 1
CFFID105 5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 11 41
CFFID106 Arachidonate 5-lipoxygenase Inhibitor 5-hydroxyeicosatetraenoi... 5 39
CFFID107 New permeability pathways Inhibitor 5-nitro-2-(3-phenylpropyla... 1 13
CFFID108 DNA polymerase Inhibitor 5-propenyl-arabinofuranosyluracil 5'-... 1 1
CFFID109 Glycogen synthase kinase-3 Inhibitor 6-bromoindirubin-3'-oxime... 2 20
CFFID110 Inosine-5'-monophosphate dehydrogenase Inhibitor 6-cl-imp Family 2 0
CFFID111 DNA topoisomerase 1 Inhibitor 7-amino-4-hydroxy-2-naphthalenes... 1 19
CFFID112 Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
CFFID113 Purine nucleoside phosphorylase Inhibitor 8-aza-dadme-immh Family 1 0
CFFID114 GTP cyclohydrolase 1 Inhibitor 8-hydroxyguanine Family 1 2
CFFID115 Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
CFFID116 Cyclin-dependent kinase 5 Inhibitor 9-nitropaullone Family 2 13
CFFID117 D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70... 16 27
CFFID118 Neuraminidase Inhibitor A-192558 Family 1 0
CFFID119 Neuraminidase Inhibitor A-315675 Family 12 20
CFFID120 P2X purinoceptor 3 Inhibitor A-317491 Family 1 2
CFFID121 Methionine aminopeptidase 2 Inhibitor A-357300 Family 1 5
CFFID122 Arachidonate 5-lipoxygenase Inhibitor A-79175 Family 1 14
CFFID123 Arachidonate 5-lipoxygenase Inhibitor AA-861 Family 1 0
CFFID124 Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor Abiet... 1 40
CFFID125 Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 6 14
CFFID126 Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
CFFID127 Topoisomerase IV Inhibitor ABT-492 Family 1 6
CFFID128 Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
CFFID129 Arachidonate 5-lipoxygenase Inhibitor Acanthus Ilicifolius Lin... 3 4
CFFID130 Glycoprotein IIb/IIIa receptor Ligand Accutin Family 4 24
CFFID131 Cannabinoid receptor 1 Ligand Acea Family 5 24
CFFID132 Nuclear factor NF-kappa-B p100 subunit Inhibitor Achp Family 1 0
CFFID133 Chloride channel protein 2 Ligand Acid-activated Omeprazole Fa... 1 1
CFFID134 CTP synthase 1 Inhibitor Acivicin Family 1 0
CFFID135 B1 bradykinin receptor Ligand Ac-lys-[leu(8)]-des-arg(9)-bk Fa... 1 0
CFFID136 Peptide deformylase, mitochondrial Inhibitor Actinonin Family 2 12
CFFID137 Glycogen phosphorylase, muscle form Inhibitor Acurea Family 1 4
CFFID138 Muscarinic acetylcholine receptor M1 Ligand Af150(s) Family 1 0
CFFID139 Muscarinic acetylcholine receptor M1 Ligand AF267B Family 1 1
CFFID140 Trifunctional purine biosynthetic protein adenosine-3 Inhibito... 2 5
CFFID141 Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
CFFID142 Adenylosuccinate synthetase Inhibitor Alanosine Family 1 1
CFFID143 Potassium voltage-gated channel subfamily H member 2 Ligand Al... 2 3
CFFID144 Voltage-dependent P/Q-type calcium channel subunit alpha-1A Li... 1 12
CFFID145 Ornithine decarboxylase Inhibitor Alpha-monofluoromethyl-3,4-d... 2 0
CFFID146 C-X-C chemokine receptor type 6 Ligand AMD3101 Family 1 0
CFFID147 Reverse transcriptase Inhibitor Amdoxovir Family 1 2
CFFID148 Tryptase Inhibitor AMG-126737 Family 1 0
CFFID149 Coagulation factor X Inhibitor T01312 Family 2 0
CFFID150 Aspartate aminotransferase, cytoplasmic Inhibitor Aminooxyacet... 1 0
CFFID151 Cannabinoid receptor 1 Ligand Oleoylethanolamide Family 8 80
CFFID152 Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
CFFID153 DNA Binder Anthramycin Family 1 0
CFFID154 Dihydroorotate dehydrogenase Inhibitor Antimycin A Family 1 0
CFFID155 Major prion protein Inhibitor Anti-prp Antibodies Family 1 6
CFFID156 Nonstructural protein 5b Inhibitor ANX-201 Family 1 0
CFFID157 Proto-oncogene tyrosine-protein kinase Src Inhibitor AP22408 F... 1 4
CFFID158 Tryptase Inhibitor APC-366 Family 2 12
CFFID159 Nitric oxide synthase, endothelial Inhibitor Ap-cav Family 1 0
CFFID160 DNA polymerase catalytic subunit Inhibitor Aphidicolin Family 2 38
CFFID161 NMDA receptor Ligand Aptiganel Hcl Family 2 82
CFFID162 Cytosolic phospholipase A2 Inhibitor Arachidonyltrifluoromethy... 4 11
CFFID163 Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CFFID164 D(2) dopamine receptor Ligand Ar-c68397aa Family 18 81
CFFID165 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 1 0
CFFID166 D(3) dopamine receptor Ligand AS-9705 Family 1 3
CFFID167 von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
CFFID168 Liver carboxylesterase 1 Inhibitor Avasimibe Family 1 1
CFFID169 B1 bradykinin receptor Ligand B-9858 Family 4 14
CFFID170 B1 bradykinin receptor Ligand B-9958 Family 6 4
CFFID171 Tryptase Inhibitor Babim Family 12 90
CFFID172 DNA gyrase subunit B Inhibitor Bay 50-7952 Family 1 0
CFFID173 DNA primase Inhibitor Bay 57-1293 Family 1 2
CFFID174 Voltage-dependent L-type calcium channel Ligand Bay K 8644 Family 1 1
CFFID175 5-hydroxytryptamine receptor Ligand Bay X3702 Family 3 12
CFFID176 Nuclear factor NF-kappa-B p100 subunit Inhibitor BAY11-7082 Fa... 2 17
CFFID177 A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
CFFID178 Peptide deformylase, mitochondrial Inhibitor BB-3497 Family 7 68
CFFID179 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase I... 2 2
CFFID180 Chymase Inhibitor Bceab Family 5 22
CFFID181 Aromatic-L-amino-acid decarboxylase Inhibitor Benserazide Family 1 1
CFFID182 Aldehyde oxidase Inhibitor Benzamidine Family 2 6
CFFID183 Glycogen synthase kinase-3 Inhibitor Benzofuran-3-yl-(indol-3-... 1 0
CFFID184 Steryl-sulfatase Inhibitor Benzomate Family 1 0
CFFID185 Reverse transcriptase Inhibitor Benzothiadiazines Family 4 21
CFFID186 GABA transporter-3 Inhibitor Beta-alanine Family 1 6
CFFID187 Alpha-2 adrenergic receptor Ligand BHT-920 Family 2 0
CFFID188 Neuropeptide Y receptor type 1 Ligand Bibp 3226 Family 43 80
CFFID189 Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
CFFID190 DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
CFFID191 Neuropeptide Y receptor type 1 Ligand BMS-193885 Family 3 11
CFFID192 Calcium-activated potassium channel subunit alpha-1 Ligand BMS... 1 1
CFFID193 Platelet activating factor, putative Inhibitor Bn 50730 Family 3 1
CFFID194 Platelet activating factor, putative Inhibitor BN52021 Family 7 14
CFFID195 Cyclooxygenase and Sodium channel Ligand BN82451 Family 1 0
CFFID196 Cyclin-dependent kinase 1 Inhibitor Borrelidin Family 1 0
CFFID197 Alpha-2A adrenergic receptor Ligand Brl 44408 Family 1 0
CFFID198 Kappa-type opioid receptor Ligand Brl 52974 Family 2 27
CFFID199 Histidine decarboxylase Inhibitor Brocresine Family 1 1
CFFID200 Alpha-2 adrenergic receptor Ligand Brominide Tartrate Family 1 0
CFFID201 Protein kinase C epsilon type Inhibitor Bryostatin-1 Family 7 4
CFFID202 Gamma-glutamylcysteine synthetase Inhibitor Bso Family 3 2
CFFID203 Estradiol 17-beta-dehydrogenase 1 Inhibitor BVT-2733 Family 3 1
CFFID204 Delta-type opioid receptor Ligand Bw 373u86 Family 31 146
CFFID205 Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
CFFID206 Arachidonate 5-lipoxygenase Inhibitor Bw A4C Family 3 18
CFFID207 Arachidonate 5-lipoxygenase Inhibitor Bw B70C Family 2 36
CFFID208 Arachidonate 5-lipoxygenase Inhibitor BW755C Family 1 6
CFFID209 C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
CFFID210 Poly [ADP-ribose] polymerase 1 Inhibitor BZ6 Family 1 0
CFFID211 Glycogen phosphorylase, muscle form Inhibitor Bzurea Family 2 20
CFFID212 Inosine-5'-monophosphate dehydrogenase 2 Inhibitor C2-MAD Family 3 24
CFFID213 Fatty acid synthase and Carnitine O-palmitoyltransferase 1, mu... 1 1
CFFID214 Arachidonate 5-lipoxygenase Inhibitor Caffeic Acid Family 3 32
CFFID215 Acetaldehyde dehydrogenase Inhibitor Calcium Carbimide Family 2 0
CFFID216 Solute carrier family 12 member Inhibitor Calyculin-a Family 3 0
CFFID217 Serine protease Inhibitor Camostat Family 1 8
CFFID218 CTP synthase 1 Inhibitor Carbodine Family 1 0
CFFID219 Scytalone dehydratase Inhibitor Carpropamid Family 5 2
CFFID220 Neutrophil elastase Inhibitor CE-1037 Family 1 4
CFFID221 Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
CFFID222 Beta-1 adrenergic receptor Ligand Cgp 20712a Family 2 2
CFFID223 Gamma-aminobutyric acid B receptor Ligand CGP-44532 Family 3 5
CFFID224 Endothelin-converting enzyme 1 and Endothelin-converting enzym... 2 12
CFFID225 Glutathione reductase, mitochondrial Inhibitor Methylene Blue ... 3 1
CFFID226 Tar rRNA Inhibitor Chimeric Small Nucleolar RNA-TAR Decoy Family 13 3
CFFID227 Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 1 2
CFFID228 Substance-P receptor Ligand CI-1021 Family 1 0
CFFID229 Coagulation factor X Inhibitor CI-1031 Family 2 16
CFFID230 Purine nucleoside phosphorylase Inhibitor CI-972 Family 1 1
CFFID231 Liver carboxylesterase 1 Inhibitor CI-976 Family 1 32
CFFID232 Glutathione S-transferase Inhibitor Cibacron Blue Family 2 12
CFFID233 Peroxisome proliferator-activated receptor gamma Ligand Ciglit... 1 31
CFFID234 Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
CFFID235 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
CFFID236 Guanylate cyclase soluble subunit beta-1 Inhibitor Cinaciguat ... 7 50
CFFID237 Dihydroorotate dehydrogenase Inhibitor Cinchoninic Acid Family 1 21
CFFID238 DNA topoisomerase 2-beta Inhibitor Ciprofloxacin+dexamethasone... 1 0
CFFID239 Hemagglutinin Inhibitor Cl 385319 Family 18 101
CFFID240 Platelet activating factor, putative Inhibitor CL-184005 Family 1 9
CFFID241 Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 31 38
CFFID242 Acetyl-CoA carboxylase 1 Inhibitor Clodinafop Family 2 17
CFFID243 Gamma-aminobutyric acid receptor Ligand Clomethiazole Family 1 5
CFFID244 2,3-bisphosphoglycerate-independent phosphoglycerate mutase In... 2 0
CFFID245 Putative histidine protein kinase Inhibitor Closantel 6 Family 1 2
CFFID246 Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 0
CFFID247 Mitogen-activated protein kinase 14 Inhibitor CNI-1493 Family 1 0
CFFID248 NF-kappa-B Inhibitor 2-oxoguaia-1,4,11(13)-trien-12,8alpha-oli... 4 18
CFFID249 DNA gyrase subunit B Inhibitor Coumermycin Family 1 0
CFFID250 Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
CFFID251 cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
CFFID252 Sorbitol dehydrogenase Inhibitor Cp-470,711 Family 9 21
CFFID253 Renin Inhibitor CP-80794 Family 16 112
CFFID254 Corticotropin-releasing factor receptor 1 Ligand CRA1000 Family 4 39
CFFID255 G protein-activated inward rectifier potassium channel 4 Ligan... 2 31
CFFID256 Tubulin Inhibitor Cryptophycin Family 1 5
CFFID257 Platelet activating factor, putative Inhibitor Cv 6209 Family 14 72
CFFID258 Adenosine receptor A1 Ligand CVT-2759 Family 1 0
CFFID259 Dihydroorotate dehydrogenase Inhibitor Cyanide Family 1 1
CFFID260 Aldehyde-alcohol dehydrogenase 2 Inhibitor Cyclobutyl Family 1 0
CFFID261 CTP synthase 1 Inhibitor Cyclopentenylcytosine Family 1 0
CFFID262 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor Cy... 1 0
CFFID263 Aldehyde-alcohol dehydrogenase 2 Inhibitor Cyclopropyl Family 1 0
CFFID264 Gamma-glutamylcysteine synthetase Inhibitor Cystamine Family 1 1
CFFID265 Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
CFFID266 Non-hemolytic phospholipase C Inhibitor D609 Family 2 0
CFFID267 Purine nucleoside phosphorylase Inhibitor Dadme-immh Family 1 0
CFFID268 Thromboxane-A synthase Inhibitor Dazoxiben Family 2 32
CFFID269 Nicotinic acetylcholine receptor Ligand DBO-83 Family 7 5
CFFID270 Alpha-1 adrenergic receptor Ligand DC-015 Family 8 25
CFFID271 Metabotropic glutamate receptor 2 Ligand Dcg Iv Family 6 9
CFFID272 3-hydroxy-3-methylglutaryl-coenzyme A reductase and Alcohol de... 7 10
CFFID273 B1 bradykinin receptor Ligand Des-arg(9)-[leu(8)]-bk Family 6 9
CFFID274 Interleukin-1 beta Inhibitor Diacerein Family 3 77
CFFID275 Protein tyrosine phosphatase Inhibitor Diamide Family 1 1
CFFID276 Enoyl-[acyl-carrier-protein] reductase [NADH] 1 and Enoyl-[acy... 1 1
CFFID277 Thyroid hormone receptor Ligand Dibrt Family 3 8
CFFID278 Dihydroorotate dehydrogenase Inhibitor Dichloroallyl Lawsone F... 1 1
CFFID279 Ribonucleoside-diphosphate reductase large subunit Inhibitor D... 2 6
CFFID280 Dihydroorotate dehydrogenase Inhibitor Dihydroorotate Family 1 2
CFFID281 Voltage-dependent L-type calcium channel Ligand Dihydropyridin... 1 0
CFFID282 Reverse transcriptase Inhibitor Dihydropyrone Family 1 1
CFFID283 DNA Binder Di-imidazole Lexitropsin Family 1 0
CFFID284 Histamine H2 receptor Ligand Dimaprit Family 2 0
CFFID285 Sigma non-opioid intracellular receptor 1 Ligand Dimemorfan Fa... 5 15
CFFID286 Putative cyclooxygenase-3 Inhibitor Dipyrone Family 1 0
CFFID287 Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
CFFID288 CTP synthase 1 Inhibitor Don Family 1 0
CFFID289 Coagulation factor X Inhibitor SN429 Family 23 100
CFFID290 NF-kappa-B Inhibitor Dtd Family 1 2
CFFID291 5-hydroxytryptamine receptor 1A Ligand Du 125530 Family 2 0
CFFID292 DNA Binder Duocarmycin Family 1 3
CFFID293 Prothrombin Inhibitor Efegatran Family 9 47
CFFID294 Prostaglandin G/H synthase 2 Inhibitor Dup-697 Family 2 10
CFFID295 5-hydroxytryptamine receptor 2A Ligand DV-7028 Family 2 10
CFFID296 Coagulation factor X Inhibitor DX9065 Family 1 0
CFFID297 Coagulation factor X Inhibitor Dx-9065a Family 2 16
CFFID298 Sodium channel Ligand E-2070 Family 1 0
CFFID299 Cathepsin S and Cysteine proteinase Inhibitor E-64 Family 5 5
CFFID300 C-C chemokine receptor type 5 Ligand E-913 Family 6 44
CFFID301 Blisterase Inhibitor Edetic Acid Family 2 5
CFFID302 Sulfur mustard-stimulated protease Inhibitor Egta Family 1 0
CFFID303 Tubulin Inhibitor Eleutherobin Family 2 0
CFFID304 Integrase Inhibitor Elvitegravir Family 2 1
CFFID305 Reverse transcriptase Inhibitor Elvucitabine Family 1 2
CFFID306 Renin Inhibitor Enalkiren Family 56 44
CFFID307 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-far... 1 3
CFFID308 Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
CFFID309 Peptide deformylase, mitochondrial Inhibitor Epiroprim Family 5 68
CFFID310 Tubulin Inhibitor Epothilone B Family 3 4
CFFID311 DNA topoisomerase 2-beta Inhibitor ER-37328 Family 1 0
CFFID312 Reverse transcriptase Inhibitor Ethyl 1-[(1h-benzimidazol-5(6)... 1 0
CFFID313 Bacterial outer membrane Inhibitor Ethylene Diamine Family 1 0
CFFID314 Platelet activating factor, putative Inhibitor F-0401 Family 1 4
CFFID315 Neuraminidase Inhibitor Fana Family 1 2
CFFID316 Farnesyl pyrophosphate synthase and Farnesyltransferase beta s... 4 30
CFFID317 Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
CFFID318 Vasopeptidase Inhibitor Fasidotril Family 3 7
CFFID319 D(4) dopamine receptor Ligand Fauc 113 Family 14 96
CFFID320 Dipeptidyl peptidase 4 Inhibitor Fe 999011 Family 10 45
CFFID321 Kappa-type opioid receptor Ligand Fedotozine Family 1 11
CFFID322 Gaba-gated chloride channel Ligand Fipronil Family 3 42
CFFID323 Neutrophil elastase Inhibitor FK-706 Family 8 85
CFFID324 ATP-citrate synthase Inhibitor (-)-hydroxycitrate Family 4 25
CFFID325 Vasopressin V2 receptor Ligand FR161282 Family 17 83
CFFID326 Mitogen-activated protein kinase 14 Inhibitor FR167653 Family 6 8
CFFID327 Glutamate-1-semialdehyde 2,1-aminomutase Inhibitor Gabaculine ... 1 2
CFFID328 Serine protease Inhibitor Gabexate Family 1 3
CFFID329 4-aminobutyrate aminotransferase, mitochondrial Inhibitor Gamm... 1 0
CFFID330 Thyroid hormone receptor beta Ligand GC-1 Family 2 62
CFFID331 Deoxyhypusine synthase Inhibitor GC7 Family 1 2
CFFID332 Neprilysin Inhibitor Thiorphan Family 41 68
CFFID333 Farnesyltransferase beta subunit, putative and Protein farnesy... 6 18
CFFID334 Glucokinase Inhibitor GKA1 Family 2 67
CFFID335 NF-kappa-B Inhibitor Gliotoxin Family 1 1
CFFID336 3-phosphoshikimate 1-carboxyvinyltransferase and Probable 3-ph... 1 0
CFFID337 NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Family 9 71
CFFID338 Apoptosis regulator Bcl-2 Inhibitor Gossypol Family 1 9
CFFID339 5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
CFFID340 Squalene monooxygenase Inhibitor Green Tea Family 5 23
CFFID341 S-adenosylmethionine decarboxylase proenzyme Inhibitor Methylg... 2 0
CFFID342 Gastrin/cholecystokinin type B receptor Ligand GV-150013 Family 2 5
CFFID343 Bile acid receptor Ligand GW4064 Family 2 58
CFFID344 Peroxisome proliferator-activated receptor gamma and Peroxisom... 15 94
CFFID345 Peroxisome proliferator-activated receptor alpha Ligand GW9578... 3 18
CFFID346 Choline kinase alpha Inhibitor Hemicholinium-3 Family 4 0
CFFID347 Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
CFFID348 Nicotinic acetylcholine receptor Ligand Hexamethonium Family 1 0
CFFID349 Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
CFFID350 DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Family 1 42
CFFID351 5-hydroxytryptamine receptor 4 Ligand Htf 919 Family 1 0
CFFID352 Peptide deformylase, mitochondrial Inhibitor Hydroxamates Family 6 17
CFFID353 Pancreatic alpha-amylase Inhibitor Hydroxycitric Acid Family 1 0
CFFID354 Noradrenergic re-uptake Inhibitor Hypericum Family 1 10
CFFID355 C-C chemokine receptor type 8 Ligand I-309 Family 1 3
CFFID356 Neutrophil elastase Inhibitor Ici 200,355 Family 9 20
CFFID357 Arachidonate 5-lipoxygenase Inhibitor Ici 207968 Family 3 7
CFFID358 Class II cytokine receptor Ligand IL-10 Family 7 45
CFFID359 Farnesyl pyrophosphate synthase Inhibitor Incadronate Family 1 5
CFFID360 Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 16 0
CFFID361 Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-di... 5 35
CFFID362 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 6 17
CFFID363 Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
CFFID364 B-lymphocyte antigen CD20 Inhibitor Iodine-131-tositumomab Family 1 0
CFFID365 NF-kappa-B Inhibitor Isohelenin Family 1 10
CFFID366 DNA Binder JM216 Family 1 0
CFFID367 Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 14 4
CFFID368 Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
CFFID369 Vanilloid receptor 1 Ligand KJM429 Family 1 0
CFFID370 Alpha-1A adrenergic receptor Ligand KMD-3213 Family 2 5
CFFID371 Plasmepsin-2 Inhibitor KNI-727 Family 3 37
CFFID372 Glucose-6-phosphate translocase Inhibitor Kodaistatin A Family 1 0
CFFID373 Tyrosine-protein phosphatase non-receptor type 1 Ligand KR6163... 1 0
CFFID374 DNA topoisomerase 1 Inhibitor KT6006 Family 3 53
CFFID375 Somatostatin receptor type 2 Ligand L-054852 Family 13 88
CFFID376 Integrase Inhibitor L17 Family 1 0
CFFID377 Geranylgeranyl transferase type-1 subunit beta Inhibitor L-269... 1 0
CFFID378 Arachidonate 5-lipoxygenase Inhibitor L-652,343 Family 1 0
CFFID379 Reverse transcriptase Inhibitor L-697,661 Family 1 25
CFFID380 Integrase Inhibitor L-708,906 Family 1 8
CFFID381 Integrase Inhibitor L-731,988 Family 1 4
CFFID382 Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 19 186
CFFID383 D(4) dopamine receptor Ligand L-745,870 Family 30 205
CFFID384 Suppressor of tumorigenicity 14 protein and Prothrombin Inhibi... 4 126
CFFID385 Prothrombin Inhibitor LB30812 Family 12 36
CFFID386 Ornithine aminotransferase, mitochondrial Inhibitor L-canaline... 2 8
CFFID387 Ferrochelatase, mitochondrial Inhibitor Lead Acetate Family 1 2
CFFID388 Glycogen synthase kinase-3 Inhibitor Lithium Chloride Family 1 0
CFFID389 Mitogen-activated protein kinase kinase kinase 1 Inhibitor LLZ... 2 0
CFFID390 Vacuolar H+-ATPase Inhibitor Lobatamide A Family 7 0
CFFID391 Phospholipase A2 Inhibitor LY178002 Family 3 30
CFFID392 Dihydroorotate dehydrogenase Inhibitor LY214352 Family 2 17
CFFID393 Transcriptional regulatory protein AlgQ Inhibitor LY266500 Family 1 3
CFFID394 Gastrin/cholecystokinin type B receptor Ligand LY288513 Family 1 3
CFFID395 Metabotropic glutamate receptor 2 Ligand LY341495 Family 4 14
CFFID396 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1 4
CFFID397 Coagulation factor X Inhibitor M55113 Family 1 8
CFFID398 Coagulation factor X Inhibitor M55551 Family 1 0
CFFID399 5-hydroxytryptamine receptor Ligand Mci Family 1 1
CFFID400 Glutamate receptor ionotropic, NMDA 2A Ligand Mdl 100,453 Family 1 3
CFFID401 Melanocortin receptor 4 Ligand Melanocortin-4 Receptor Antagon... 1 56
CFFID402 Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Family 9 69
CFFID403 Fatty-acid amide hydrolase 1 Inhibitor Methoxy Arachidonyl Flu... 3 2
CFFID404 5-hydroxytryptamine 2 receptor Ligand Metrenperone Family 3 4
CFFID405 23S rRNA Inhibitor Micrococcin Family 1 1
CFFID406 Cyclin-dependent kinase 1 and Prostaglandin G/H synthase 2 Inh... 1 0
CFFID407 Serine hydroxymethyltransferase Inhibitor Mimosine Family 1 4
CFFID408 Receptor tyrosine-protein kinase erbB-2 Inhibitor Mini-antibod... 1 0
CFFID409 Farnesyl pyrophosphate synthase Inhibitor Minodronate Family 1 0
CFFID410 Prostaglandin E synthase Inhibitor L-655240 Family 3 46
CFFID411 Alpha-2C adrenergic receptor Ligand MK-912 Family 1 3
CFFID412 Tryptase Inhibitor Mol 6131 Family 1 0
CFFID413 Neutrophil elastase Inhibitor MR-889 Family 2 2
CFFID414 Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 24 47
CFFID415 Calcium-dependent chloride channel-1 Ligand MSI-1956 Family 1 0
CFFID416 5-hydroxytryptamine receptor 2B Ligand MT-500 Family 8 39
CFFID417 Glucose-6-phosphate translocase Inhibitor Mumbaistatin Family 3 11
CFFID418 Muscarinic acetylcholine receptor Ligand Muscarine Family 1 3
CFFID419 Aspartate transcarbamoylase catalytic subunit PyrB Inhibitor N... 1 1
CFFID420 Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 2
CFFID421 Peptide deformylase, mitochondrial Inhibitor N-alkyl Urea Hydr... 1 0
CFFID422 5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
CFFID423 M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
CFFID424 Poly(ADP-ribose) glycohydrolase Inhibitor N-bis-(3-phenyl-prop... 3 7
CFFID425 Tyrosine-protein kinase JAK3 Inhibitor NC1153 Family 1 1
CFFID426 Farnesyl pyrophosphate synthase Inhibitor NE21650 Family 1 0
CFFID427 Thyroid hormone receptor Ligand NH-3 Family 1 0
CFFID428 Thyroid hormone receptor Ligand NH-4 Family 1 0
CFFID429 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1 0
CFFID430 Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
CFFID431 Chymase Inhibitor NK3201 Family 1 0
CFFID432 Steryl-sulfatase Inhibitor Nortropinyl-arylsulfonylurea 3 Family 1 1
CFFID433 Glycogen synthase kinase-3 Inhibitor NP12 Family 3 5
CFFID434 Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
CFFID435 Neuropeptide Y receptor type 1 Ligand NPY-1 Antagonist Family 1 0
CFFID436 Neuropeptide Y receptor type 5 Ligand NPY-5 Receptor Antagonis... 1 1
CFFID437 Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
CFFID438 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... 2 7
CFFID439 Angiogenin Inhibitor Oltipraz Family 1 8
CFFID440 Vasopressin V1a receptor and Vasopressin V2 receptor Ligand OP... 12 94
CFFID441 Dihydroorotase, putative and Dihydroorotate dehydrogenase Inhi... 2 0
CFFID442 Receptor-type tyrosine-protein phosphatase S Ligand Orthovanad... 1 0
CFFID443 Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
CFFID444 Sodium-dependent noradrenaline transporter Inhibitor Oxaprotil... 1 0
CFFID445 Cyclin-dependent kinase 5 and Cyclin-dependent kinase 8 Inhibi... 2 3
CFFID446 Cyclin-dependent kinase 8 Inhibitor Oxindole 94 Family 2 3
CFFID447 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphok... 1 0
CFFID448 Dipeptidyl peptidase 4 Inhibitor P32/98 Family 1 0
CFFID449 Urokinase-type plasminogen activator Inhibitor PAI-1 Family 5 7
CFFID450 Urokinase-type plasminogen activator Inhibitor PAI-2 Family 1 0
CFFID451 Cyclin-dependent kinase 4 and Cyclin-dependent kinase 6 Inhibi... 2 3
CFFID452 Endothelin-1 receptor Ligand PD156707 Family 41 211
CFFID453 Mitogen-activated protein kinase kinase kinase 1 and Mitogen-a... 1 0
CFFID454 Mitogen-activated protein kinase kinase kinase 1 and Mitogen-a... 1 0
CFFID455 Peptide deformylase, mitochondrial Inhibitor Tylophorinidine F... 7 1
CFFID456 Protein tyrosine phosphatase Inhibitor Pervanadate Family 1 0
CFFID457 Gamma-aminobutyric acid B receptor Ligand Phaclofen Family 1 3
CFFID458 Protein kinase C delta type Inhibitor 13-acetylphorbol Family 10 8
CFFID459 Tyrosine kinase Inhibitor PKI166 Family 17 198
CFFID460 5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
CFFID461 Transcription factor AP-1 Inhibitor PNRI-299 Family 1 0
CFFID462 Dihydroorotate dehydrogenase Inhibitor Polyporic Acid Family 4 13
CFFID463 Gp29 Inhibitor Ppa Family 3 2360
CFFID464 Prothrombin Inhibitor Ppack Family 5 4
CFFID465 Nuclear receptor subfamily 1 group I member 2 Ligand Pregnenol... 1 1
CFFID466 Alanine racemase Inhibitor Propionate Family 1 2
CFFID467 Inhibitor of nuclear factor kappa-B kinase subunit epsilon and... 1 4
CFFID468 Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2 11
CFFID469 DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inh... 1 0
CFFID470 Uridine 5'-monophosphate synthase Inhibitor Pyrazofurin Family 1 0
CFFID471 Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 2 12
CFFID472 NF-kappa-B Inhibitor Pyrrolidine Dithiocarbamate Family 2 2
CFFID473 Dopamine D2-like receptor Ligand Quinelorane Family 1 4
CFFID474 Acetyl-CoA carboxylase 1 Inhibitor Quizalofop Family 1 13
CFFID475 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor R 8012... 1 1
CFFID476 Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
CFFID477 Arachidonate 5-lipoxygenase Inhibitor R-85355 Family 1 0
CFFID478 Tumor necrosis factor ligand superfamily member 13B Inhibitor ... 1 0
CFFID479 Isoleucine--tRNA ligase and Isoleucine--tRNA ligase, cytoplasm... 1 0
CFFID480 RNA polymerase Inhibitor Rifalazil Family 1 0
CFFID481 Matrix metalloproteinase-9 Inhibitor Ro 28-2653 Family 2 0
CFFID482 5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
CFFID483 Muscarinic acetylcholine receptor Ligand Rs 86 Family 1 1
CFFID484 Type-1 angiotensin II receptor Ligand RTI-76 Family 3 6
CFFID485 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor RW... 1 0
CFFID486 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor RW... 1 0
CFFID487 Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
CFFID488 Glucose-6-phosphate translocase Inhibitor S 3025 Family 1 0
CFFID489 CAMP-phosphodiesterase Inhibitor S(-)enantiomer Of 3-(3-hydrox... 1 0
CFFID490 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 1 0
CFFID491 Neuropeptide Y receptor type 1 and Neuropeptide Y receptor typ... 1 0
CFFID492 Glucose-6-phosphate translocase Inhibitor S-4048 Family 1 0
CFFID493 Prostaglandin D2 receptor Ligand S-5751 Family 6 6
CFFID494 Coronavirus main proteinase Inhibitor Sabadinine Family 1 0
CFFID495 Muscarinic acetylcholine receptor M1 Ligand Sabcomeline Family 2 1 1
CFFID496 Dihydroorotate dehydrogenase Inhibitor Salicylhydroxamic Acid ... 2 8
CFFID497 Alpha-2 adrenergic receptor Ligand Saline Family 1 0
CFFID498 Vasopeptidase Inhibitor Sampatrilat Family 25 9
CFFID499 Interleukin-6 receptor subunit beta Ligand Sant7 Family 6 8
CFFID500 Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
showing 1 to 500 of 4226. <<First <Prev Page 1 Next> Last>>

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21315 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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