CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   

Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

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Browsing Superfamily of Functional Category "Clinical Trial Drug"


IDNameFamilies
CFSCD1 Tyrosine-protein phosphatase non-receptor type 6 Ligand Sodium... 1
CFSCD2 Stromelysin-1 and Peroxisome proliferator-activated receptor d... 2
CFSCD3 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 2
CFSCD4 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 7
CFSCD5 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 3
CFSCD6 Aurora kinase B and Aurora kinase C Inhibitor SNS-314 Superfamily 5
CFSCD7 Cyclin-dependent kinase 2 and Cyclin-dependent kinase 7 Inhibi... 7
CFSCD8 RAC-gamma serine/threonine-protein kinase and Ribosomal protei... 6
CFSCD9 Aurora kinase B and Aurora kinase A Inhibitor CYC116 Superfamily 12
CFSCD10 Integrin alpha-4 Inhibitor R1295 Superfamily 7
CFSCD11 72 kDa type IV collagenase and Interstitial collagenase Inhibi... 3
CFSCD12 Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 4
CFSCD13 Cathepsin G and Neutrophil elastase Inhibitor Dermolastin Supe... 3
CFSCD14 Platelet-activating factor acetylhydrolase Inhibitor Gsk 65903... 2
CFSCD15 Mitogen-activated protein kinase 12 Inhibitor SB681323 Superfa... 7
CFSCD16 Transient receptor potential cation channel subfamily V member... 4
CFSCD17 Transient receptor potential cation channel subfamily V member... 2
CFSCD18 Macrophage colony-stimulating factor 1 Inhibitor ABT-869 Super... 3
CFSCD19 Nitric oxide synthase, endothelial Inhibitor Acclaim Superfamily 3
CFSCD20 Metabotropic glutamate receptor 5 Ligand ADX-48621 Superfamily 8
CFSCD21 Heat shock protein HSP 90-alpha Inhibitor Alvespimycin Family 1
CFSCD22 Gastrin-releasing peptide receptor and Arachidonate 5-lipoxyge... 10
CFSCD23 C-X-C chemokine receptor type 4 Ligand AMD-3100 Superfamily 4
CFSCD24 Leukotriene B4 receptor 1 Ligand Amelubant Superfamily 7
CFSCD25 Toll-like receptor 9 and Melanin-concentrating hormone recepto... 6
CFSCD26 Transient receptor potential cation channel subfamily V member... 2
CFSCD27 Transient receptor potential cation channel subfamily V member... 4
CFSCD28 Tumor necrosis factor Inhibitor AN0128 Superfamily 4
CFSCD29 Cholesteryl ester transfer protein Inhibitor Anacetrapib Super... 2
CFSCD30 B2 bradykinin receptor Ligand Anatibant Superfamily 4
CFSCD31 Glucose-dependent insulinotropic receptor Ligand APD668 Superf... 2
CFSCD32 Protein kinase C beta type and Glycogen synthase kinase-3 beta... 7
CFSCD33 Kinesin-like protein KIF11 Inhibitor ARRY-520 Superfamily 2
CFSCD34 Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Superfa... 9
CFSCD35 Heat shock protein HSP 90-alpha Inhibitor AT13387 Superfamily 3
CFSCD36 Cyclin-dependent kinase 2 Inhibitor AT7519 Superfamily 2
CFSCD37 Aurora kinase B and Aurora kinase A Inhibitor AT9283 Superfamily 2
CFSCD38 secretase and Farnesyltransferase beta subunit, putative Binde... 4
CFSCD39 Transient receptor potential cation channel subfamily V member... 7
CFSCD40 Purine nucleoside phosphorylase Inhibitor BCX-34 Superfamily 4
CFSCD41 Purine nucleoside phosphorylase Inhibitor Forodesine Superfamily 3
CFSCD42 Histidine decarboxylase Inhibitor Bf-derm1 Superfamily 7
CFSCD43 Serine/threonine-protein kinase PLK1 Inhibitor Bi 6727 Superfa... 5
CFSCD44 Mitogen-activated protein kinase 12 Inhibitor Birb 796 Superfa... 3
CFSCD45 Microsomal triglyceride transfer protein large subunit Inhibit... 4
CFSCD46 Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 6
CFSCD47 Cyclin-dependent kinase 2 and Cyclin-dependent kinase 4 Inhibi... 4
CFSCD48 Mitogen-activated protein kinase 8 Inhibitor CC-401 Superfamily 9
CFSCD49 Lysosomal alpha-glucosidase Inhibitor Celgosivir Superfamily 2
CFSCD50 Neuropeptide Y receptor type 5 Ligand CGP71683A Superfamily 4
CFSCD51 Neurotensin receptor type 1 and Ceramide glucosyltransferase B... 10
CFSCD52 Puromycin-sensitive aminopeptidase Inhibitor CHR-2797 Superfamily 8
CFSCD53 Histamine H3 receptor Ligand Cipralisant Superfamily 3
CFSCD54 HER and Macrophage migration inhibitory factor Binder Superfamily 3
CFSCD55 Farnesyltransferase beta subunit, putative Binder Superfamily 3
CFSCD56 Corticotropin-releasing factor receptor 1 Ligand CRF-1 Antagon... 4
CFSCD57 Serine/threonine-protein kinase PLK1 Inhibitor CYC-800 Superfa... 2
CFSCD58 Sodium/glucose cotransporter 2 Inhibitor Empagliflozin Superfa... 2
CFSCD59 Platelet-activating factor acetylhydrolase Inhibitor Darapladi... 3
CFSCD60 Cholecystokinin receptor type A Ligand Dexloxiglumide Superfamily 6
CFSCD61 Arachidonate 5-lipoxygenase-activating protein Inhibitor DG031... 8
CFSCD62 Prostaglandin E2 receptor EP3 subtype Ligand DG041 Superfamily 4
CFSCD63 Leukotriene A-4 hydrolase Inhibitor DG051 Superfamily 2
CFSCD64 Gamma-secretase subunit APH-1B Inhibitor E2012 Superfamily 10
CFSCD65 Egl nine homolog 2 Inhibitor FG-4592 Superfamily 4
CFSCD66 Histone deacetylase 4 Inhibitor FK-228 Superfamily 2
CFSCD67 Cyclin-dependent kinase 2 Inhibitor Flavopiridol Superfamily 2
CFSCD68 Cholecystokinin receptor type A Ligand Gi 181771 Superfamily 3
CFSCD69 Nuclear factor NF-kappa-B p100 subunit Inhibitor GMX1777 Super... 5
CFSCD70 Telomerase protein component 1 Inhibitor GRN163L Superfamily 7
CFSCD71 Serine/threonine-protein kinase PLK1 Inhibitor GSK461364 Super... 3
CFSCD72 Centromere-associated protein E Inhibitor GSK-923295 Superfamily 7
CFSCD73 Glycine receptor subunit beta Ligand Gw 468816 Superfamily 4
CFSCD74 Serine/threonine-protein kinase PLK1 Inhibitor HMN-214 Superfa... 9
CFSCD75 B2 bradykinin receptor Ligand Icatibant Superfamily 2
CFSCD76 Microsomal triglyceride transfer protein large subunit Inhibit... 6
CFSCD77 Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor INCB1... 3
CFSCD78 C-C chemokine receptor type 2 Ligand INCB3284 Family 1
CFSCD79 Heat shock protein HSP 90-alpha Inhibitor IPI-504 Superfamily 2
CFSCD80 Glucosylceramidase Inhibitor Isofagomine Tartrate Superfamily 2
CFSCD81 Kinesin-like protein KIF11 Inhibitor Ispinesib Superfamily 7
CFSCD82 Motilin receptor Ligand KOS-2187 Superfamily 3
CFSCD83 Poly [ADP-ribose] polymerase 1 Inhibitor KU-0059436 Superfamily 3
CFSCD84 B2 bradykinin receptor Ligand Labradimil Superfamily 2
CFSCD85 Squalene synthase Inhibitor Lapaquistat Acetate Superfamily 4
CFSCD86 Serine/threonine-protein kinase PLK1 Inhibitor LC-445 Family 1
CFSCD87 Cholecystokinin receptor type A Ligand Lintitript Superfamily 3
CFSCD88 Nitric oxide synthase, endothelial Inhibitor L-NAME Superfamily 2
CFSCD89 Nitric oxide synthase, endothelial Inhibitor L-NMMA Superfamily 2
CFSCD90 Farnesyltransferase beta subunit, putative Inhibitor Lonafarni... 4
CFSCD91 Glucokinase Inhibitor Lonidamine Superfamily 4
CFSCD92 Leukotriene B4 receptor 1 Ligand Ltb 019 Superfamily 3
CFSCD93 Metabotropic glutamate receptor 3 Ligand LY354740 Superfamily 2
CFSCD94 Metabotropic glutamate receptor 3 Ligand LY404039 Family 1
CFSCD95 Fructose-1,6-bisphosphatase 1 Inhibitor MB07803 Superfamily 5
CFSCD96 Peroxisome proliferator-activated receptor delta Ligand MBX-80... 2
CFSCD97 Neurotensin receptor type 1 Ligand Meclinertant Superfamily 2
CFSCD98 Aurora kinase A Inhibitor MLN8054 Superfamily 8
CFSCD99 Hepatocyte growth factor receptor and Mast/stem cell growth fa... 5
CFSCD100 Histone deacetylase 1 Inhibitor MS-275 Superfamily 3
CFSCD101 Corticotropin-releasing factor receptor 1 Ligand NBI-34041 Family 1
CFSCD102 Corticotropin-releasing factor receptor 1 Ligand NBI-37582 Sup... 2
CFSCD103 Melanin-concentrating hormone receptor 1 Ligand NGD-4715 Super... 3
CFSCD104 Transient receptor potential cation channel subfamily V member... 9
CFSCD105 Phosphodiesterase and Thromboxane-A synthase Inhibitor NM-702 ... 5
CFSCD106 Nitric oxide synthase, brain Inhibitor NXN-188 Superfamily 4
CFSCD107 Cathepsin K Inhibitor Odanacatib Superfamily 6
CFSCD108 Calcitonin gene-related peptide 1 Inhibitor Olcegepant Superfa... 2
CFSCD109 5-hydroxytryptamine receptor 2A and Serine/threonine-protein k... 6
CFSCD110 Prostaglandin E2 receptor EP4 subtype Ligand ONO-4819 Superfamily 5
CFSCD111 Neuromedin-K receptor Ligand Osanetant Superfamily 15
CFSCD112 RAC-gamma serine/threonine-protein kinase Inhibitor Perifosine... 2
CFSCD113 Nuclear factor NF-kappa-B p100 subunit Inhibitor PG-490-88 Sup... 2
CFSCD114 Sphingosine kinase 2 Inhibitor Phenoxodiol Superfamily 6
CFSCD115 Heparanase Inhibitor PI-88 Superfamily 2
CFSCD116 Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor P... 2
CFSCD117 Glycogen phosphorylase, muscle form Inhibitor PSN357 Superfamily 13
CFSCD118 Vascular endothelial growth factor Inhibitor PTC299 Superfamily 3
CFSCD119 Thioredoxin Inhibitor PX-12 Superfamily 5
CFSCD120 Histone deacetylase 1 Inhibitor PXD101 Superfamily 2
CFSCD121 Integrin beta-1 Inhibitor R411 Superfamily 7
CFSCD122 Tyrosine-protein kinase SYK Binder Superfamily 2
CFSCD123 Cathepsin K and Neuronal acetylcholine receptor subunit alpha-... 7
CFSCD124 Signal transducer and activator of transcription 3 Inhibitor R... 5
CFSCD125 B-lymphocyte antigen CD19 Inhibitor SAR3419 Superfamily 2
CFSCD126 Neuromedin-K receptor Ligand SB222200 Superfamily 7
CFSCD127 Transient receptor potential cation channel subfamily V member... 4
CFSCD128 Cyclin-dependent kinase 2 Inhibitor Seliciclib Superfamily 12
CFSCD129 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3
CFSCD130 Hepatocyte growth factor receptor Ligand SGX523 Superfamily 4
CFSCD131 Heat shock protein HSP 90-alpha Inhibitor SNX-5422 Superfamily 3
CFSCD132 Substance-K receptor Ligand Sr 144190 Superfamily 4
CFSCD133 Coagulation factor X and Prothrombin Inhibitor SR-123781A Supe... 2
CFSCD134 NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 S... 3
CFSCD135 Interleukin-12 subunit alpha Inhibitor STA-5326 Superfamily 4
CFSCD136 Heat shock protein HSP 90-alpha Inhibitor STA-9090 Superfamily 3
CFSCD137 Steryl-sulfatase Inhibitor Stx 64 Superfamily 4
CFSCD138 C-X-C chemokine receptor type 3 Ligand T487 Superfamily 4
CFSCD139 Transcription factor AP-1 Inhibitor T-5224 Superfamily 1
CFSCD140 Neuromedin-K receptor Ligand Talnetant Superfamily 3
CFSCD141 72 kDa type IV collagenase Inhibitor Tanomastat Superfamily 2
CFSCD142 Cholecystokinin receptor type A Ligand Tarazepide Superfamily 8
CFSCD143 Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 6
CFSCD144 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6
CFSCD145 Fibroblast growth factor receptor 3 Ligand TKI258 Superfamily 4
CFSCD146 Cholesteryl ester transfer protein Inhibitor Torcetrapib Super... 7
CFSCD147 Coagulation factor IX Inhibitor TTP889 Superfamily 2
CFSCD148 Growth hormone secretagogue receptor type 1 Ligand TZP-101 Sup... 6
CFSCD149 Phospholipase A2, membrane associated and Genomic RNA for RNA-... 12
CFSCD150 Tyrosine-protein kinase Lck and Aurora kinase B Inhibitor VX-6... 4
CFSCD151 Mitogen-activated protein kinase 12 Inhibitor VX-702 Superfamily 8
CFSCD152 Mitogen-activated protein kinase 12 Inhibitor VX-745 Superfamily 2
CFSCD153 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 6
CFSCD154 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2
CFSCD155 Hepatocyte growth factor receptor and Vascular endothelial gro... 13
CFSCD156 Serine/threonine-protein kinase PLK1 Inhibitor Zk-thiazolidino... 1
CFSCD157 Adenosine receptor A1 and Muscarinic acetylcholine receptor M1... 3
CFSCD158 Arachidonate 5-lipoxygenase Inhibitor Linazolast Superfamily 7
CFSCD159 Aldose reductase Inhibitor Sorbinil Superfamily 6
CFSCD160 Hemagglutinin Inhibitor Arbidol Superfamily 1
CFSCD161 Dihydroorotate dehydrogenase Inhibitor Brequinar Superfamily 8
CFSCD162 Arachidonate 5-lipoxygenase Inhibitor Lonapalene Superfamily 4
CFSCD163 C-C chemokine receptor type 5 Ligand Vicriviroc Superfamily 7
CFSCD164 Thromboxane A2 receptor Ligand Ifetroban Superfamily 6
CFSCD165 Calcium-activated potassium channel subunit alpha-1 Ligand ICA... 4
CFSCD166 Retinoic acid receptor alpha Ligand LG100268 Superfamily 4
CFSCD167 Muscarinic acetylcholine receptor M1 Ligand Sabcomeline Superf... 3
CFSCD168 23S rRNA Inhibitor Evernimicin Family 1
CFSCD169 Aldose reductase Inhibitor Zenarestat Superfamily 2
CFSCD170 Prostaglandin G/H synthase 2 Inhibitor Rpr 200765a Superfamily 12
CFSCD171 Neuraminidase Inhibitor Peramivir Superfamily 3
CFSCD172 Adenosine receptor A2a Binder Superfamily 3
CFSCD173 Thymidylate synthase Inhibitor Plevitrexed (r)-isomer Superfamily 8
CFSCD174 DNA topoisomerase 2-beta Binder Superfamily 2 4
CFSCD175 Nonstructural protein 5b Inhibitor T-705 Family 1
CFSCD176 Reverse transcriptase and Receptor-type tyrosine-protein kinas... 6
CFSCD177 Lipase Inhibitor Cetilistat Superfamily 4
CFSCD178 Multidrug resistance protein Inhibitor Tariquidar Superfamily 4
CFSCD179 Endothelin-1 receptor Ligand Atrasentan Superfamily 4
CFSCD180 Type-2 angiotensin II receptor Ligand PS433540 Superfamily 2
CFSCD181 Arachidonate 5-lipoxygenase Inhibitor Licofelone Superfamily 7
CFSCD182 Muscarinic acetylcholine receptor M1 Ligand Talsaclidine Fumar... 1
CFSCD183 Multidrug resistance-associated protein 1 Inhibitor Benzbromar... 8
CFSCD184 Arachidonate 5-lipoxygenase Inhibitor MK-591 Superfamily 6
CFSCD185 Adenosine receptor A2a Ligand KW-6002 Superfamily 5
CFSCD186 Thromboxane A2 receptor Ligand Bibv 308 Superfamily 5
CFSCD187 Thromboxane A2 receptor and Potassium-competitive acid Binder ... 4
CFSCD188 Dopamine reuptake Inhibitor Brasofensine Superfamily 3
CFSCD189 Toll-like receptor 7 Ligand Isatoribine Superfamily 3
CFSCD190 Cannabinoid receptor 1 Ligand Taranabant Superfamily 4
CFSCD191 Muscarinic acetylcholine receptor M1 Ligand Xanomeline Tartrat... 3
CFSCD192 Tubulin beta chain Inhibitor Tasidotin Superfamily 3
CFSCD193 Melatonin receptor type 1A Ligand Agomelatine Superfamily 7
CFSCD194 P2Y purinoceptor 12 Inhibitor Ar-c69931 Mx Superfamily 4
CFSCD195 Acetyl-CoA acetyltransferase, mitochondrial Binder Superfamily 5
CFSCD196 D(2) dopamine receptor Ligand Nomifensine Superfamily 5
CFSCD197 Dopamine reuptake Inhibitor Amineptine Superfamily 9
CFSCD198 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 4
CFSCD199 Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 5
CFSCD200 Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Su... 11
CFSCD201 Epidermal growth factor receptor and Receptor tyrosine-protein... 3
CFSCD202 Epidermal growth factor receptor and Receptor tyrosine-protein... 5
CFSCD203 Vascular endothelial growth factor receptor 2 Ligand Ptk787/zk... 3
CFSCD204 Vascular endothelial growth factor receptor 2 Ligand CP-547632... 5
CFSCD205 Mast/stem cell growth factor receptor Kit and Vascular endothe... 8
CFSCD206 Macrophage colony-stimulating factor 1 and Vascular endothelia... 3
CFSCD207 Vascular endothelial growth factor receptor 2 Ligand Cediranib... 4
CFSCD208 Vascular endothelial growth factor receptor 2 Ligand BAY-57-93... 3
CFSCD209 Fibroblast growth factor receptor 3 and RAF proto-oncogene ser... 4
CFSCD210 Platelet-derived growth factor receptor Ligand CP-868596 Super... 11
CFSCD211 Fibroblast growth factor receptor 2 and Fibroblast growth fact... 9
CFSCD212 Angiopoietin-1 receptor and Vascular endothelial growth factor... 2
CFSCD213 Dual specificity mitogen-activated protein kinase kinase Inhib... 3
CFSCD214 Insulin-like growth factor 1 receptor Ligand AEW-541 Superfamily 17
CFSCD215 Cyclin-dependent kinase 4 Inhibitor PD-332991 Superfamily 8
CFSCD216 Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 4
CFSCD217 Abelson tyrosine-protein kinase 2 and Proto-oncogene tyrosine-... 4
CFSCD218 NAD-dependent protein deacetylase sirtuin-1 Inhibitor GSK18407... 1
CFSCD219 Oxytocin receptor Ligand GSK221149 Superfamily 5
CFSCD220 Histamine H3 receptor Ligand GSK239512 Superfamily 3
CFSCD221 cAMP-specific 3',5'-cyclic phosphodiesterase 4A Inhibitor GSK2... 6
CFSCD222 Substance-P receptor Ligand GSK424887 Superfamily 9
CFSCD223 Corticotropin-releasing factor receptor 1 Ligand GSK561679 Sup... 1
CFSCD224 Muscarinic acetylcholine receptor M1 Ligand GSK573719 Superfamily 2
CFSCD225 D(3) dopamine receptor Ligand GSK618334 Superfamily 3
CFSCD226 Beta-2 adrenergic receptor Ligand GW642444 Superfamily 3
CFSCD227 Orexin receptor type 1 Ligand SB-649868 Superfamily 2
CFSCD228 C-X-C chemokine receptor type 2 Ligand SB-656933 Superfamily 4
CFSCD229 Glucocorticoid receptor Ligand GW685698X Superfamily 11
CFSCD230 5-hydroxytryptamine receptor 6 Ligand SB-742457 Superfamily 5
CFSCD231 Histamine H1 receptor and Histamine H3 receptor Ligand GSK8357... 3
CFSCD232 Motilin receptor Ligand GSK962040 Superfamily 4
CFSCD233 Histamine H1 receptor and Histamine H3 receptor Ligand GSK1004... 5
CFSCD234 Sodium channel Ligand GSK1014802 Superfamily 4
CFSCD235 Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Superfa... 6
CFSCD236 Dual specificity mitogen-activated protein kinase kinase Inhib... 1
CFSCD237 Integrase Inhibitor S-349572 Family 1
CFSCD238 Mu-type opioid receptor Ligand GSK1521498 Superfamily 2
CFSCD239 Bcl-2-like protein 1 and Apoptosis regulator Bcl-2 Inhibitor A... 2
CFSCD240 Peroxisome proliferator-activated receptor alpha Ligand Alegli... 5
CFSCD241 Dipeptidyl peptidase 4 Inhibitor Alogliptin Superfamily 3
CFSCD242 Angiopoietin-1 and Angiopoietin-2 Inhibitor Amg 386 Family 1
CFSCD243 Dual specificity mitogen-activated protein kinase kinase Inhib... 2
CFSCD244 NAD(P)H dehydrogenase [quinone] 1 Inhibitor Apaziquone Superfa... 1
CFSCD245 Coagulation factor X Inhibitor Apixaban Superfamily 13
CFSCD246 Atrial natriuretic peptide receptor 1 Ligand Ataciguat Superfa... 7
CFSCD247 Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 17
CFSCD248 Cannabinoid receptor 1 Ligand AVE1625 Superfamily 2
CFSCD249 Nicotinic acetylcholine receptor Ligand AZD0328 Superfamily 13
CFSCD250 Prothrombin Inhibitor AZD0837 Family 1
CFSCD251 Aurora kinase B and Aurora kinase A Inhibitor AZD1152 Superfamily 6
CFSCD252 Macrophage metalloelastase Inhibitor AZD1236 Superfamily 8
CFSCD253 Cannabinoid receptor 1 Ligand AZD1940 Family 1
CFSCD254 Prostaglandin D2 receptor 2 Ligand AZD1981 Superfamily 8
CFSCD255 Cannabinoid receptor 1 Ligand AZD2207 Superfamily 4
CFSCD256 Gamma-aminobutyric acid B receptor Binder Superfamily 3
CFSCD257 Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor AZD40... 2
CFSCD258 C-C chemokine receptor type 5 Ligand AZD5672 Superfamily 10
CFSCD259 Myeloperoxidase Inhibitor AZD5904 Superfamily 5
CFSCD260 Prostaglandin D2 receptor 2 Ligand AZD5985 Superfamily 3
CFSCD261 Dual specificity mitogen-activated protein kinase kinase Inhib... 4
CFSCD262 Gamma-aminobutyric acid A receptor Ligand AZD6280 Superfamily 2
CFSCD263 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8
CFSCD264 Serine/threonine-protein kinase Chk1 Inhibitor AZD7762 Superfa... 3
CFSCD265 Serine/threonine-protein kinase mTOR Inhibitor AZD8055 Superfa... 6
CFSCD266 Dual specificity mitogen-activated protein kinase kinase Binde... 2
CFSCD267 DNA topoisomerase 1 Inhibitor Beta-lapachone Superfamily 4
CFSCD268 B-lymphocyte antigen CD20 Binder Superfamily 5
CFSCD269 P2Y purinoceptor 12 Inhibitor Brilinta Superfamily 3
CFSCD270 Poly [ADP-ribose] polymerase 1 Inhibitor BSI-201 Superfamily 4
CFSCD271 Prostaglandin E2 receptor EP2 subtype Ligand CP-533536 Superfa... 6
CFSCD272 Cholesteryl ester transfer protein Inhibitor CP-800569 Superfa... 4
CFSCD273 Cannabinoid receptor 1 Binder Superfamily 10
CFSCD274 Tumor necrosis factor Inhibitor Cytofab Superfamily 4
CFSCD275 Tumor necrosis factor receptor superfamily member 5 Ligand Dac... 9
CFSCD276 Cholesteryl ester transfer protein Inhibitor Dalcetrapib Super... 3
CFSCD277 Tumor necrosis factor receptor superfamily member 10A and Tumo... 2
CFSCD278 Alpha-1A adrenergic receptor Ligand Dutasteride & Tamsulosin S... 3
CFSCD279 Glucagon receptor Ligand Dwlip-gcgrrx Superfamily 4
CFSCD280 Integrin alpha-4 Inhibitor Firategrast Superfamily 4
CFSCD281 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1
CFSCD282 Aurora kinase B and Aurora kinase C Binder Superfamily 10
CFSCD283 Sodium/glucose cotransporter 2 Inhibitor Isis-5glt2rx Superfamily 2
CFSCD284 C-reactive protein Inhibitor ISIS-CRP Superfamily 8
CFSCD285 Neuronal acetylcholine receptor subunit alpha-4 Ligand Isproni... 5
CFSCD286 Dipeptidyl peptidase 4 Inhibitor Linagliptin Superfamily 5
CFSCD287 Mitogen-activated protein kinase 14 Inhibitor Losmapimod Super... 3
CFSCD288 5-hydroxytryptamine receptor Ligand Lu AA21004 Superfamily 7
CFSCD289 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor MK-0... 4
CFSCD290 Gamma secretase Inhibitor MK-0752 Superfamily 7
CFSCD291 Wee1-like protein kinase Inhibitor MK-1775 Superfamily 2
CFSCD292 RAC-gamma serine/threonine-protein kinase Inhibitor MK-2206 Su... 1
CFSCD293 Poly [ADP-ribose] polymerase 1 and Serine/threonine-protein ki... 8
CFSCD294 Multiple kinase and Aurora kinase A Binder Superfamily 7
CFSCD295 Adenosine receptor A1 Ligand MK-7418 Superfamily 4
CFSCD296 Hepatocyte growth factor receptor Ligand MK-8033 Superfamily 6
CFSCD297 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 4
CFSCD298 NEDD8-activating enzyme E1 catalytic subunit Inhibitor MLN4924... 5
CFSCD299 Mast/stem cell growth factor receptor Kit and Vascular endothe... 17
CFSCD300 Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 7
CFSCD301 B-lymphocyte antigen CD20 Inhibitor Ofatumumab Family 1
CFSCD302 Substance-P receptor Ligand Orvepitant Superfamily 9
CFSCD303 Coagulation factor X Inhibitor Otamixaban Superfamily 5
CFSCD304 Epidermal growth factor receptor and Receptor tyrosine-protein... 4
CFSCD305 Coagulation factor X Inhibitor PD-348292 Superfamily 4
CFSCD306 Metabotropic glutamate receptor 1 Ligand PF-1913539 Superfamily 13
CFSCD307 D(3) dopamine receptor Ligand PF-217830 Superfamily 3
CFSCD308 DNA damage-inducible transcript 4 protein Inhibitor PF-4523655... 2
CFSCD309 Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 2
CFSCD310 E3 ubiquitin-protein ligase Mdm2 Inhibitor R7112 Family 1
CFSCD311 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 2
CFSCD312 Glucokinase Inhibitor R7201 Superfamily 4
CFSCD313 HIV protease Inhibitor Danoprevir Superfamily 2
CFSCD314 Placenta growth factor Inhibitor R7334 Superfamily 4
CFSCD315 Sodium/glucose cotransporter 2 Inhibitor Remogliflozin Etabona... 4
CFSCD316 Toll-like receptor 4 Ligand Resatorvid Superfamily 2
CFSCD317 Extracellular calcium-sensing receptor Ligand Ronacaleret Supe... 2
CFSCD318 Peroxisome proliferator-activated receptor gamma Ligand Rosigl... 5
CFSCD319 Dipeptidyl peptidase 4 Binder Superfamily 3
CFSCD320 Corticotropin-releasing factor receptor 1 Ligand SSR125543 Sup... 2
CFSCD321 Dipeptidyl peptidase 4 Inhibitor TAK-100 Superfamily 5
CFSCD322 Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Supe... 9
CFSCD323 Gonadotropin-releasing hormone receptor Ligand TAK-385 Superfa... 1
CFSCD324 Coagulation factor X Inhibitor TAK-442 Superfamily 4
CFSCD325 KiSS-1 receptor Ligand TAK-683 Superfamily 5
CFSCD326 Hepatocyte growth factor receptor Ligand TAK-701 Superfamily 3
CFSCD327 Aurora kinase B Inhibitor TAK-901 Superfamily 4
CFSCD328 Endothelin-1 receptor Ligand Zibotentan Superfamily 4
CFSCD329 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5
CFSCD330 Muscarinic acetylcholine receptor Ligand Aclidinium Bromide Su... 7
CFSCD331 Adenosine receptor A3 and Pigment epithelium-derived factor Bi... 7
CFSCD332 Protein kinase C Inhibitor AEB07 Superfamily 3
CFSCD333 Thrombopoietin receptor Ligand AKR-501 Superfamily 5
CFSCD334 Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 5
CFSCD335 Urokinase-type plasminogen activator Inhibitor Amediplase Supe... 6
CFSCD336 D(2) dopamine receptor Ligand Aplindore Fumarate Superfamily 3
CFSCD337 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Apre... 7
CFSCD338 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 4
CFSCD339 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 3
CFSCD340 Kappa-type opioid receptor Ligand Asimadoline Superfamily 4
CFSCD341 Progesterone receptor Ligand Asoprisnil Superfamily 3
CFSCD342 Signal transducer and activator of transcription 3 Inhibitor A... 6
CFSCD343 D(3) dopamine receptor Ligand AVE-5997EF Superfamily 5
CFSCD344 Potassium voltage-gated channel subfamily A member 5 Ligand Az... 1
CFSCD345 Glutamate receptor AMPA subtype Ligand Becampanel Superfamily 3
CFSCD346 Cyclooxygenase Inhibitor Benzydamine Superfamily 5
CFSCD347 C-C chemokine receptor type 3 Ligand Bertilimumab?? Superfamily 4
CFSCD348 Adenosine receptor A2a Ligand BG-9928 Superfamily 2
CFSCD349 Glutamate receptor AMPA subtype and Noradrenaline uptake Ligan... 4
CFSCD350 D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A Bin... 7
CFSCD351 Adenosine receptor A2a and Serine/threonine-protein kinase mTO... 6
CFSCD352 Synaptic vesicle glycoprotein 2A Inhibitor Brivaracetam Superf... 5
CFSCD353 5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 6
CFSCD354 Sodium channel Ligand Carisbamate Superfamily 3
CFSCD355 Integrin alpha-4 Inhibitor CDP323 Superfamily 5
CFSCD356 Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4
CFSCD357 Calcitonin gene-related peptide 1 Inhibitor Cizolirtine Superf... 5
CFSCD358 Arachidonate 5-lipoxygenase Inhibitor CJ-13610 Superfamily 3
CFSCD359 NMDA receptor Ligand CNS-5161 Superfamily 3
CFSCD360 Corticotropin-releasing factor receptor 1 Ligand Cp-316,311 Su... 10
CFSCD361 Corticotropin-releasing factor receptor 2 Ligand Crf-r2 Antago... 2
CFSCD362 Neuromedin-K receptor and Substance-K receptor Ligand CS-003 S... 4
CFSCD363 Glutamate receptor AMPA subtype Ligand CX-516 Superfamily 2
CFSCD364 Substance-P receptor Binder Superfamily 6
CFSCD365 Reverse transcriptase Inhibitor Dapivirine Superfamily 3
CFSCD366 5-hydroxytryptamine receptor 3A Ligand DDP-225 Superfamily 4
CFSCD367 Adenosine receptor A2a and Alpha-2 adrenergic receptor Binder ... 5
CFSCD368 Translocator protein Inhibitor Dextofisopam Superfamily 4
CFSCD369 P2Y purinoceptor 2 Inhibitor Diquafosol Superfamily 10
CFSCD370 Substance-K receptor and Substance-P receptor Ligand DNK-333 S... 7
CFSCD371 Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 6
CFSCD372 Potassium voltage-gated channel subfamily A member 5 Ligand Dr... 3
CFSCD373 NMDA receptor Ligand D-serine Superfamily 3
CFSCD374 Vascular endothelial growth factor receptor 2 Binder Superfamily 8
CFSCD375 Tubulin Inhibitor E 7974 Superfamily 6
CFSCD376 Sigma non-opioid intracellular receptor 1 Ligand E-5842 Family 1
CFSCD377 NMDA receptor Ligand EAA-090 Superfamily 3
CFSCD378 Sodium channel Ligand Eslicarbazepine Acetate Superfamily 7
CFSCD379 Thrombopoietin receptor Ligand Eltrombopag Superfamily 1
CFSCD380 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2
CFSCD381 Translocator protein and Toll-like receptor 7 Binder Superfamily 5
CFSCD382 Growth hormone receptor Binder Superfamily 3
CFSCD383 Substance-P receptor Ligand Ezlopitant Superfamily 13
CFSCD384 Glutamate receptor 1 Ligand Farampator Superfamily 3
CFSCD385 Interferon gamma Inhibitor Fumaric Acid Superfamily 5
CFSCD386 DNA Binder Glufosfamide Superfamily 3
CFSCD387 5-hydroxytryptamine receptor 2A and D(1B) dopamine receptor Li... 2
CFSCD388 Glutamate carboxypeptidase 2 Inhibitor GPI-16072 Superfamily 3
CFSCD389 Gp29 Inhibitor GRN163 Family 1
CFSCD390 Dopamine reuptake and Noradrenergic re-uptake Inhibitor GSK372... 4
CFSCD391 Beta-2 adrenergic receptor Ligand GSK642444 Superfamily 4
CFSCD392 Prostaglandin G/H synthase 2 Inhibitor GSK-644784 Superfamily 2
CFSCD393 Peroxisome proliferator-activated receptor alpha and Peroxisom... 2
CFSCD394 Prostaglandin G/H synthase 2 Inhibitor GW-406381 Superfamily 4
CFSCD395 Beta-3 adrenergic receptor Ligand GW-427353 Superfamily 7
CFSCD396 Adenosine receptor A2a Ligand GW-493838 Superfamily 2
CFSCD397 Corticotropin-releasing factor receptor 1 Ligand GW876008 Supe... 18
CFSCD398 Genomic RNA for RNA-dependent RNA polymerase gene (clone HCV-J... 2
CFSCD399 Interleukin-6 and Interleukin-1 beta Binder Superfamily 4
CFSCD400 Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Binder ... 11
CFSCD401 Interleukin-1 Inhibitor K-832 Superfamily 3
CFSCD402 5-hydroxytryptamine receptor 3A Ligand KB-6806 Superfamily 3
CFSCD403 Voltage-gated sodium channel Ligand Lacosamide Superfamily 2
CFSCD404 D(2) dopamine receptor Ligand Lamectacin Superfamily 5
CFSCD405 C-X-C motif chemokine 2 Inhibitor Laquinamod Superfamily 5
CFSCD406 D(1B) dopamine receptor Ligand LE-300 Superfamily 6
CFSCD407 5-hydroxytryptamine receptor 2C Ligand Lorcaserin Superfamily 4
CFSCD408 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 8
CFSCD409 NMDA receptor Ligand Magnesium Family 2 1
CFSCD410 Apoptosis regulator Bcl-2 Inhibitor MCI-186 Superfamily 4
CFSCD411 C-C chemokine receptor type 2 Ligand MLN1202 Superfamily 3
CFSCD412 5-hydroxytryptamine receptor 1A Ligand MN-305 Superfamily 4
CFSCD413 Adenosine receptor A2a Ligand MRE-0094 Superfamily 3
CFSCD414 Sigma non-opioid intracellular receptor 1 Ligand MS-377 Superf... 4
CFSCD415 D(2) dopamine receptor Ligand N-0923 Superfamily 3
CFSCD416 NMDA receptor Ligand Neramexane Superfamily 4
CFSCD417 Sodium-dependent noradrenaline transporter Inhibitor Neri Iv S... 3
CFSCD418 Glutamate receptor AMPA subtype Ligand Ns 1209 Family 1
CFSCD419 cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor ONO-... 1
CFSCD420 Glucocorticoid receptor Ligand Org 34517/34850 Superfamily 4
CFSCD421 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 6
CFSCD422 Histone deacetylase 1 Inhibitor Panobinostat Superfamily 5
CFSCD423 D(2) dopamine receptor and D(3) dopamine receptor Ligand PD-15... 4
CFSCD424 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7
CFSCD425 D(4) dopamine receptor Ligand PD-165167 Superfamily 8
CFSCD426 Mucosal addressin cell adhesion molecule 1 Inhibitor PF-005476... 6
CFSCD427 Carbonic anhydrase and Gamma-aminobutyric acid receptor Ligand... 2
CFSCD428 Voltage-dependent L-type calcium channel Ligand Pinaverium Bro... 2
CFSCD429 Tumor necrosis factor Inhibitor Pirfenidone Superfamily 5
CFSCD430 5-hydroxytryptamine receptor 1A and Sigma non-opioid intracell... 2
CFSCD431 5-hydroxytryptamine receptor 4 Ligand Pumosetrag Superfamily 2
CFSCD432 Beta-2 adrenergic receptor Ligand QVA-149 Superfamily 2
CFSCD433 Substance-P receptor Ligand R 673 Superfamily 13
CFSCD434 Cytochrome P450 26A1 Inhibitor Rambazole Superfamily 6
CFSCD435 C-X-C chemokine receptor type 1 and C-X-C chemokine receptor t... 2
CFSCD436 Transient receptor potential cation channel subfamily V member... 3
CFSCD437 Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1
CFSCD438 Glutamate receptor ionotropic, NMDA 2B Ligand RGH-896 Superfamily 6
CFSCD439 Rho-associated protein kinase 1 Inhibitor Rho-kinase Inhibitor... 2
CFSCD440 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 5
CFSCD441 D(2) dopamine receptor Ligand Rotigotine Patch Superfamily 5
CFSCD442 Sodium-dependent dopamine transporter Inhibitor RTI-336 Superf... 5
CFSCD443 5-hydroxytryptamine receptor 1A and D(3) dopamine receptor Lig... 8
CFSCD444 Vasopressin V2 receptor Ligand Satavaptan Superfamily 2
CFSCD445 C-X-C chemokine receptor type 2 Ligand SB-265610 Superfamily 2
CFSCD446 D(3) dopamine receptor Ligand SB-277011 Superfamily 6
CFSCD447 Synaptic vesicle glycoprotein 2A Inhibitor Seletracetam Family 1
CFSCD448 Beta-2 adrenergic receptor and D(2) dopamine receptor Ligand S... 1
CFSCD449 Neutrophil elastase Inhibitor Sivelestat Sodium Hydrate Superf... 5
CFSCD450 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 5
CFSCD451 5-hydroxytryptamine receptor 1A and Cannabinoid receptor 1 Lig... 3
CFSCD452 Adenosine receptor A1 Ligand SLV320 Superfamily 4
CFSCD453 DNA topoisomerase 2-beta Inhibitor SNS-595 Superfamily 3
CFSCD454 Histone deacetylase and Protein kinase C beta type Binder Supe... 5
CFSCD455 D(4) dopamine receptor Ligand SPI-376 Superfamily 6
CFSCD456 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 1
CFSCD457 Sigma non-opioid intracellular receptor 1 Ligand SSR-125047 Su... 3
CFSCD458 Vasopressin V1b receptor Ligand SSR149415 Superfamily 4
CFSCD459 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 3
CFSCD460 3-hydroxy-3-methylglutaryl-coenzyme A reductase Inhibitor Stat... 3
CFSCD461 D(2) dopamine receptor Ligand Sumanirole Superfamily 2
CFSCD462 Adenosine receptor A2a Ligand T-62 Superfamily 4
CFSCD463 Substance-P receptor Ligand TAK-637 Superfamily 8
CFSCD464 Tumor necrosis factor Inhibitor Talactoferrin Alfa Superfamily 5
CFSCD465 Glutamate receptor AMPA subtype Ligand Talampanel Superfamily 5
CFSCD466 Tyrosine-protein kinase JAK2 Inhibitor TG101348 Superfamily 5
CFSCD467 Tumor necrosis factor Inhibitor Tgaac-94 Superfamily 6
CFSCD468 Glutamate receptor AMPA subtype Ligand TRO-19622 Superfamily 3
CFSCD469 D(3) dopamine receptor Ligand U-99194A Superfamily 3
CFSCD470 Interleukin-12 subunit alpha and Interleukin-23 subunit alpha ... 4
CFSCD471 Substance-P receptor Ligand Vestipitant Superfamily 5
CFSCD472 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 18
CFSCD473 D(2) dopamine receptor Ligand Y-931 Superfamily 3
CFSCD474 5-hydroxytryptamine receptor 2A and D(1B) dopamine receptor Li... 5
CFSCD475 Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 6
CFSCD476 mRNA of Glucagon receptor Ligand Isis 325568 Superfamily 2
CFSCD477 Aurora kinase A Inhibitor ENMD-2076 Superfamily 2
CFSCD478 Aurora kinase B and Aurora kinase A Inhibitor PF-03814735 Supe... 6
CFSCD479 Aurora kinase B and Aurora kinase A Inhibitor PHA-739358 Super... 4
CFSCD480 Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 2
CFSCD481 Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 6
CFSCD482 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13
CFSCD483 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3
CFSCD484 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5
CFSCD485 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 13
CFSCD486 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5
CFSCD487 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3
CFSCD488 RAC-gamma serine/threonine-protein kinase Inhibitor VQD-002 Su... 4
CFSCD489 Serine/threonine-protein kinase mTOR Inhibitor OSI-027 Family 1
CFSCD490 C-C chemokine receptor type 5 Ligand Pro 140 Superfamily 6
CFSCD491 Glutamate receptor ionotropic, kainate 1 Ligand LY293558 Super... 2
CFSCD492 Histone deacetylase 1 Inhibitor Sodium Butyrate Superfamily 2
CFSCD493 Dipeptidyl peptidase 4 Inhibitor ABT-279 Superfamily 2
CFSCD494 Histone deacetylase 1 Inhibitor AN-9 Superfamily 9
CFSCD495 Glutamate receptor ionotropic, NMDA 2B Ligand Besonprodil Supe... 2
CFSCD496 Envelope glycoprotein gp120 Inhibitor BMS-488043 Superfamily 6
CFSCD497 Gamma-aminobutyric acid A receptor Ligand ELB-139 Superfamily 3
CFSCD498 Metabotropic glutamate receptor 2 and Metabotropic glutamate r... 2
CFSCD499 Heat shock protein 90, putative Inhibitor Nvp-auy922 Superfamily 3
CFSCD500 Glutamate receptor AMPA subtype Ligand S-18986 Superfamily 4
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Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21665 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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