CFam Chemical Families Database
BIDD Pharmainformatics Databases

Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

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Browsing Superfamily of Functional Category "Investigative Drug"

CFSID1 Sodium- and Gamma-aminobutyric acid A receptor Binder Superfamily 3
CFSID2 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4
CFSID3 Nicotinic acetylcholine receptor alpha2 / alpha3 Ligand Ibogai... 5
CFSID4 Hepatitis C Virus RNA-dependent RNA Polymerase Inhibitor AG-02... 2
CFSID5 Platelet activating factor, putative Inhibitor Web 2086 Superf... 3
CFSID6 Nociceptin receptor Ligand J-113397 Superfamily 2
CFSID7 Prothrombin and Neuropeptide Y receptor type 1 Binder Superfamily 4
CFSID8 4-hydroxyphenylpyruvate dioxygenase and Gamma-aminobutyric aci... 8
CFSID9 Aldose reductase Binder Superfamily 2
CFSID10 Nicotinic acetylcholine receptor Ligand Dianicline Superfamily 4
CFSID11 Gamma-aminobutyric acid uptake Inhibitor Nnc 711 Superfamily 3
CFSID12 5-hydroxytryptamine receptor 2A Ligand Fananserin Superfamily 3
CFSID13 Neuropeptide Y receptor type 1 Ligand GI-264879A Superfamily 4
CFSID14 Glutamate receptor AMPA subtype Ligand GYKI-47261 Superfamily 10
CFSID15 DNA topoisomerase Inhibitor Ahma Superfamily 4
CFSID16 ATP-sensitive inward rectifier potassium channel 11 Ligand Ipt... 4
CFSID17 Mitogen-activated protein kinase 1 and Mitogen-activated prote... 6
CFSID18 Neuropeptide Y receptor type 5 Ligand Npy5ra-972 Superfamily 4
CFSID19 Neuropeptide Y receptor type 1 Ligand PD-160170 Superfamily 3
CFSID20 D(3) dopamine receptor Ligand RGH-1756 Superfamily 4
CFSID21 Prothrombin and Neuromedin-K receptor Binder Superfamily 7
CFSID22 D(2) dopamine receptor and D(3) dopamine receptor Ligand S3250... 3
CFSID23 Caspase-3 and Aldose reductase Binder Superfamily 4
CFSID24 Substance-K receptor Ligand SLV-332 Superfamily 3
CFSID25 D(4) dopamine receptor Ligand Sonepiprazole Superfamily 5
CFSID26 Delta-type opioid receptor and Potassium voltage-gated channel... 6
CFSID27 Progesterone receptor Ligand Tanaproget Superfamily 3
CFSID28 C-C chemokine receptor type 3 Ligand YM-355179 Superfamily 8
CFSID29 Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 4
CFSID30 Reverse transcriptase Inhibitor 3-benzylamino-5-ethyl-6-methyl... 3
CFSID31 Metabotropic glutamate receptor 5 Ligand LY525327 Superfamily 2
CFSID32 Heat shock protein 90, putative and Heat shock protein HSP 90-... 2
CFSID33 Dipeptidyl peptidase 4 Inhibitor Denagliptin Superfamily 8
CFSID34 Histone deacetylase 1 and Histone deacetylase 2 Inhibitor Depu... 3
CFSID35 Histone deacetylase 1 Inhibitor Hc-toxin Superfamily 2
CFSID36 5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 6
CFSID37 Histone deacetylase 1 and Arachidonate 5-lipoxygenase Binder S... 6
CFSID38 Metabotropic glutamate receptor 5 Ligand Mcn3377 Superfamily 2
CFSID39 Carbonic anhydrase 2 and Dipeptidyl peptidase 4 Binder Superfa... 8
CFSID40 C-C chemokine receptor type 5 Binder Superfamily 3
CFSID41 C-C chemokine receptor type 5 Ligand Tak-220 Superfamily 8
CFSID42 5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2
CFSID43 72 kDa type IV collagenase Inhibitor Batimastat Superfamily 9
CFSID44 72 kDa type IV collagenase Inhibitor Metastat Superfamily 3
CFSID45 Melanocortin receptor 3 and Melanocortin receptor 4 Binder Sup... 7
CFSID46 XL-888 Superfamily 6
CFSID47 PF-4217903 Superfamily 5
CFSID48 PF-3758309 Superfamily 2
CFSID49 Cytochrome P450 2D6 and Delta-type opioid receptor Binder Supe... 6
CFSID50 Cathepsin B and Cathepsin L1 Binder Superfamily 7
CFSID51 Bis(5'-adenosyl)-triphosphatase Inhibitor Fructose Superfamily 2
CFSID52 Granotapide Superfamily 4
CFSID53 Eprotirome Superfamily 3
CFSID54 PF-4136309 Superfamily 5
CFSID55 SPD-556 Superfamily 2
CFSID56 WAY-162545 Superfamily 4
CFSID57 6-phosphogluconate dehydrogenase, decarboxylating Inhibitor (2... 3
CFSID58 Glutamate receptor 1 and Adenosine receptor A3 Binder Superfamily 5
CFSID59 Ornithine decarboxylase Inhibitor (2r,5r)-delta-methyl-alpha-a... 1
CFSID60 Gamma-aminobutyric acid uptake Inhibitor (r)-nipecotic Acid Su... 4
CFSID61 5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Superfamily 9
CFSID62 5-hydroxytryptamine receptor 6 Ligand [125i]sb-258585 Superfamily 2
CFSID63 Cyclin-dependent kinase 1 and Arachidonate 12-lipoxygenase, 12... 3
CFSID64 Peroxisome proliferator-activated receptor gamma Ligand 15-deo... 3
CFSID65 Arachidonate 5-lipoxygenase and Peroxisome proliferator-activa... 3
CFSID66 Heat shock protein 90, putative Inhibitor 17-allylamino-17-dem... 1
CFSID67 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2
CFSID68 Metabotropic glutamate receptor 5 and Arachidonate 5-lipoxygen... 10
CFSID69 Gp29 Inhibitor 2,3,7-trichloro-5-nitroquinoxaline (tnqx) Super... 2
CFSID70 DNA topoisomerase 1 Inhibitor 2,3-dimethoxybenzo[i]phenanthrid... 2
CFSID71 Glutathione reductase, mitochondrial Inhibitor 2,4,6 Trinitrob... 1
CFSID72 Isocitrate lyase Inhibitor 3-bromopyruvate Superfamily 2
CFSID73 Alanine racemase Inhibitor 3-fluorovinylglycine Superfamily 2
CFSID74 Kynureninase Inhibitor 3-methoxydesaminokynurenine Superfamily 4
CFSID75 Isocitrate lyase Inhibitor 3-nitropropionate Superfamily 2
CFSID76 Reverse transcriptase and Hemoglobin subunit alpha Binder Supe... 6
CFSID77 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 2
CFSID78 Prothrombin and Urokinase-type plasminogen activator Inhibitor... 4
CFSID79 6-phosphogluconate dehydrogenase, decarboxylating and 2-dehydr... 5
CFSID80 Dihydroorotase, putative and Dihydroorotate dehydrogenase Bind... 3
CFSID81 Androgen receptor and Oestrogen receptor Binder Superfamily 6
CFSID82 DNA polymerase Inhibitor 5-propenyl-arabinofuranosyluracil 5'-... 4
CFSID83 Glycogen synthase kinase-3 Inhibitor 6-bromoindirubin-3'-oxime... 3
CFSID84 Inosine-5'-monophosphate dehydrogenase Inhibitor 6-cl-imp Supe... 2
CFSID85 DNA topoisomerase 1 Inhibitor 7-amino-4-hydroxy-2-naphthalenes... 8
CFSID86 Adenosine receptor A1 and Adenosine receptor A2a Binder Superf... 8
CFSID87 Purine nucleoside phosphorylase and Hypoxanthine-guanine-xanth... 3
CFSID88 GTP cyclohydrolase 1 Inhibitor 8-hydroxyguanine Superfamily 2
CFSID89 Histone deacetylase and Cyclin-dependent kinase 5 Binder Super... 3
CFSID90 D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70... 1
CFSID91 Neuraminidase Inhibitor A-192558 Superfamily 6
CFSID92 Neuraminidase Inhibitor A-315675 Superfamily 2
CFSID93 P2X purinoceptor 3 and Oxysterols receptor LXR-beta Binder Sup... 6
CFSID94 Methionine aminopeptidase 2 Inhibitor A-357300 Superfamily 2
CFSID95 Arachidonate 5-lipoxygenase Inhibitor A-79175 Family 1
CFSID96 Arachidonate 5-lipoxygenase Inhibitor AA-861 Family 1
CFSID97 Glycogen phosphorylase, muscle form and Corticosteroid 11-beta... 4
CFSID98 Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5
CFSID99 Platelet activating factor, putative Inhibitor ABT-491 Superfa... 5
CFSID100 Galanin receptor type 2 and Galanin receptor type 1 Binder Sup... 6
CFSID101 Arachidonate 5-lipoxygenase Inhibitor Acanthus Ilicifolius Lin... 5
CFSID102 Carbonic anhydrase 2 and Carbonic anhydrase 12 Binder Superfamily 4
CFSID103 Cannabinoid receptor 1 and Fatty-acid amide hydrolase 1 Binder... 3
CFSID104 Nuclear factor NF-kappa-B p100 subunit Inhibitor Achp Family 1
CFSID105 Carbonic anhydrase 2 and Carbonic anhydrase 1 Binder Superfamily 9
CFSID106 CTP synthase 1 Inhibitor Acivicin Family 1
CFSID107 B1 bradykinin receptor Ligand Ac-lys-[leu(8)]-des-arg(9)-bk Fa... 1
CFSID108 Interstitial collagenase and Peptide deformylase, mitochondria... 6
CFSID109 Muscarinic acetylcholine receptor M1 Ligand Af150(s) Superfamily 3
CFSID110 Muscarinic acetylcholine receptor M1 Ligand AF267B Superfamily 2
CFSID111 Trifunctional purine biosynthetic protein adenosine-3 Inhibito... 5
CFSID112 Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 3
CFSID113 Adenylosuccinate synthetase Inhibitor Alanosine Superfamily 2
CFSID114 Potassium voltage-gated channel subfamily H member 2 Ligand Al... 2
CFSID115 Voltage-dependent P/Q-type calcium channel subunit alpha-1A Li... 2
CFSID116 Ornithine decarboxylase Inhibitor Alpha-monofluoromethyl-3,4-d... 2
CFSID117 C-X-C chemokine receptor type 6 Ligand AMD3101 Family 1
CFSID118 Tryptase Inhibitor AMG-126737 Superfamily 4
CFSID119 Coagulation factor X and Epidermal growth factor receptor Bind... 2
CFSID120 Glucose-6-phosphate 1-dehydrogenase and Aspartate aminotransfe... 4
CFSID121 Cannabinoid receptor 1 Ligand Oleoylethanolamide Superfamily 5
CFSID122 Corticotropin-releasing factor receptor 1 and Proto-oncogene t... 4
CFSID123 Somatostatin receptor type 4 Binder Superfamily 5
CFSID124 Dihydroorotate dehydrogenase Inhibitor Antimycin A Superfamily 3
CFSID125 Melanocortin receptor 4 and Major prion protein Binder Superfa... 6
CFSID126 Nonstructural protein 5b Inhibitor ANX-201 Family 1
CFSID127 Proto-oncogene tyrosine-protein kinase Src Binder Superfamily 2
CFSID128 Tryptase and Kappa-type opioid receptor Binder Superfamily 5
CFSID129 Nitric oxide synthase, endothelial Inhibitor Ap-cav Superfamily 6
CFSID130 DNA polymerase catalytic subunit Inhibitor Aphidicolin Superfa... 3
CFSID131 NMDA receptor Ligand Aptiganel Hcl Superfamily 1
CFSID132 Alpha-2C adrenergic receptor and 5-hydroxytryptamine receptor ... 7
CFSID133 D(2) dopamine receptor Ligand Ar-c68397aa Superfamily 8
CFSID134 Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inh... 2
CFSID135 D(3) dopamine receptor Ligand AS-9705 Superfamily 2
CFSID136 von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 4
CFSID137 Liver carboxylesterase 1 Inhibitor Avasimibe Superfamily 3
CFSID138 B1 bradykinin receptor Binder Superfamily 2
CFSID139 Tryptase and Adenosine receptor A1 Binder Superfamily 9
CFSID140 DNA gyrase subunit B Inhibitor Bay 50-7952 Family 1
CFSID141 DNA primase Inhibitor Bay 57-1293 Superfamily 6
CFSID142 Voltage-dependent L-type calcium channel Ligand Bay K 8644 Sup... 1
CFSID143 Nuclear factor NF-kappa-B p100 subunit Inhibitor BAY11-7082 Su... 5
CFSID144 Disintegrin and A disintegrin Binder Superfamily 3
CFSID145 Peptide deformylase, mitochondrial Inhibitor BB-3497 Superfamily 4
CFSID146 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase I... 3
CFSID147 Chymase Inhibitor Bceab Superfamily 5
CFSID148 Aromatic-L-amino-acid decarboxylase Inhibitor Benserazide Supe... 2
CFSID149 Aldehyde oxidase Inhibitor Benzamidine Superfamily 2
CFSID150 Glycogen synthase kinase-3 Inhibitor Benzofuran-3-yl-(indol-3-... 2
CFSID151 Reverse transcriptase Inhibitor Benzothiadiazines Superfamily 4
CFSID152 GABA transporter-3 Inhibitor Beta-alanine Superfamily 2
CFSID153 Integrin alpha-4 Inhibitor BIO-1211 Superfamily 4
CFSID154 Kappa-type opioid receptor and Delta-type opioid receptor Bind... 5
CFSID155 Neuropeptide Y receptor type 1 Ligand BMS-193885 Superfamily 5
CFSID156 Calcium-activated potassium channel subunit alpha-1 Ligand BMS... 4
CFSID157 Platelet activating factor, putative Inhibitor Bn 50730 Superf... 3
CFSID158 Platelet activating factor, putative Inhibitor BN52021 Superfa... 2
CFSID159 Cyclooxygenase and Sodium channel Ligand BN82451 Superfamily 2
CFSID160 Cyclin-dependent kinase 1 Inhibitor Borrelidin Superfamily 3
CFSID161 Alpha-2A adrenergic receptor Ligand Brl 44408 Superfamily 4
CFSID162 Melanocortin receptor and Kappa-type opioid receptor Binder Su... 4
CFSID163 Histidine decarboxylase Inhibitor Brocresine Superfamily 4
CFSID164 Isoleucine--tRNA ligase and Protein kinase C epsilon type Bind... 2
CFSID165 Thymidylate synthase and Gamma-glutamylcysteine synthetase Bin... 3
CFSID166 Estradiol 17-beta-dehydrogenase 1 Inhibitor BVT-2733 Superfamily 2
CFSID167 Delta-type opioid receptor and Tyrosine-protein kinase SYK Bin... 9
CFSID168 D(1A) dopamine receptor and Arachidonate 5-lipoxygenase Binder... 5
CFSID169 Arachidonate 5-lipoxygenase Binder Superfamily 3
CFSID170 Arachidonate 5-lipoxygenase Inhibitor BW755C Superfamily 3
CFSID171 C-C chemokine receptor type 1 Ligand BX-471 Superfamily 5
CFSID172 Poly [ADP-ribose] polymerase 1 Inhibitor BZ6 Superfamily 2
CFSID173 Glycogen phosphorylase, muscle form Inhibitor Bzurea Superfamily 3
CFSID174 Estradiol 17-beta-dehydrogenase 1 and Inosine-5'-monophosphate... 4
CFSID175 Fatty acid synthase and Carnitine O-palmitoyltransferase 1, mu... 3
CFSID176 Epidermal growth factor receptor and Arachidonate 5-lipoxygena... 4
CFSID177 Acetaldehyde dehydrogenase Inhibitor Calcium Carbimide Superfa... 2
CFSID178 Solute carrier Family 2 1
CFSID179 Serine protease Inhibitor Camostat Superfamily 3
CFSID180 CTP synthase 1 Binder Superfamily 2
CFSID181 Neutrophil elastase Inhibitor CE-1037 Superfamily 2
CFSID182 Beta-3 adrenergic receptor Ligand Cgp 12177 Superfamily 3
CFSID183 Beta-1 adrenergic receptor Ligand Cgp 20712a Superfamily 7
CFSID184 Gamma-aminobutyric acid B receptor Binder Superfamily 2 2
CFSID185 Endothelin-converting enzyme 1 and Endothelin-converting enzym... 2
CFSID186 Glutathione reductase, mitochondrial Inhibitor Methylene Blue ... 6
CFSID187 Tar rRNA Inhibitor Chimeric Small Nucleolar RNA-TAR Decoy Supe... 1
CFSID188 Coagulation factor X Inhibitor CI-1031 Superfamily 9
CFSID189 Purine nucleoside phosphorylase Inhibitor CI-972 Superfamily 2
CFSID190 Cytochrome P450 1B1 and Liver carboxylesterase 1 Binder Superf... 5
CFSID191 P2Y purinoceptor 12 and Glutathione S-transferase Binder Super... 3
CFSID192 Integrin alpha-V and Integrin beta-3 Binder Superfamily 5
CFSID193 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 4
CFSID194 DNA topoisomerase 2-beta Inhibitor Ciprofloxacin+dexamethasone... 4
CFSID195 Cathepsin S and Hemagglutinin Binder Superfamily 5
CFSID196 Platelet activating factor, putative Inhibitor CL-184005 Super... 3
CFSID197 Histamine H3 receptor and Histamine H4 receptor Ligand Clobenp... 3
CFSID198 Gamma-aminobutyric acid receptor Ligand Clomethiazole Superfamily 3
CFSID199 2,3-bisphosphoglycerate-independent phosphoglycerate mutase In... 2
CFSID200 Indoleamine 2,3-dioxygenase 1 and Glycogen synthase kinase-3 b... 5
CFSID201 Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 2
CFSID202 Adenosine receptor A3 and Mitogen-activated protein kinase 14 ... 3
CFSID203 NF-kappa-B Binder Superfamily 3
CFSID204 DNA gyrase subunit B and DNA topoisomerase 2-beta Binder Super... 2
CFSID205 cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4
CFSID206 Sorbitol dehydrogenase Inhibitor Cp-470,711 Superfamily 2
CFSID207 Renin Inhibitor CP-80794 Superfamily 6
CFSID208 Corticotropin-releasing factor receptor 1 Ligand CRA1000 Super... 6
CFSID209 G protein-activated inward rectifier potassium channel 4 Ligan... 7
CFSID210 Tubulin Inhibitor Cryptophycin Superfamily 2
CFSID211 Adenosine receptor A1 and Gamma-aminobutyric acid receptor sub... 2
CFSID212 Dihydroorotate dehydrogenase Inhibitor Cyanide Family 1
CFSID213 Aldehyde-alcohol dehydrogenase 2 Inhibitor Cyclobutyl Superfamily 2
CFSID214 Aldehyde-alcohol dehydrogenase 2 Inhibitor Cyclopropyl Family 1
CFSID215 Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 3
CFSID216 Non-hemolytic phospholipase C Inhibitor D609 Superfamily 3
CFSID217 Purine nucleoside phosphorylase Inhibitor Dadme-immh Family 1
CFSID218 Aromatase and Thromboxane-A synthase Binder Superfamily 9
CFSID219 Nicotinic acetylcholine receptor Ligand DBO-83 Superfamily 3
CFSID220 Alpha-1 adrenergic receptor and Alpha-1A adrenergic receptor B... 5
CFSID221 Metabotropic glutamate receptor 2 Ligand Dcg Iv Superfamily 2
CFSID222 Adenosine receptor A2a and Adenosine receptor A1 Binder Superf... 8
CFSID223 B1 bradykinin receptor Ligand Des-arg(9)-[leu(8)]-bk Superfamily 2
CFSID224 Interleukin-1 beta and Indoleamine 2,3-dioxygenase 1 Binder Su... 7
CFSID225 Protein tyrosine phosphatase Inhibitor Diamide Superfamily 3
CFSID226 Adenosylhomocysteinase and Thyroid hormone receptor Binder Sup... 5
CFSID227 Ribonucleoside-diphosphate reductase large subunit Inhibitor D... 2
CFSID228 Dihydroorotate dehydrogenase Inhibitor Dihydroorotate Superfamily 3
CFSID229 Cathepsin B and Voltage-dependent L-type calcium channel Binde... 2
CFSID230 Reverse transcriptase Inhibitor Dihydropyrone Superfamily 2
CFSID231 DNA Binder Di-imidazole Lexitropsin Superfamily 5
CFSID232 Histamine H2 receptor Ligand Dimaprit Family 1
CFSID233 Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3
CFSID234 Putative cyclooxygenase-3 Inhibitor Dipyrone Superfamily 4
CFSID235 Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 S... 4
CFSID236 Coagulation factor X Inhibitor SN429 Superfamily 7
CFSID237 NF-kappa-B and Prolyl endopeptidase Binder Superfamily 3
CFSID238 5-hydroxytryptamine receptor 1A Ligand Du 125530 Superfamily 5
CFSID239 DNA Binder Duocarmycin Superfamily 2
CFSID240 Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 5
CFSID241 5-hydroxytryptamine 2 receptor and 5-hydroxytryptamine recepto... 2
CFSID242 Coagulation factor X Inhibitor DX9065 Family 1
CFSID243 Coagulation factor X Inhibitor Dx-9065a Superfamily 4
CFSID244 Sodium channel Ligand E-2070 Superfamily 4
CFSID245 Cathepsin S and Cysteine proteinase Inhibitor E-64 Superfamily 2
CFSID246 Blisterase Inhibitor Edetic Acid Superfamily 4
CFSID247 Plasminogen and Sulfur mustard-stimulated protease Binder Supe... 3
CFSID248 Tubulin Inhibitor Eleutherobin Family 1
CFSID249 Integrase Inhibitor Elvitegravir Superfamily 3
CFSID250 Reverse transcriptase Inhibitor Elvucitabine Family 1
CFSID251 Renin Inhibitor Enalkiren Superfamily 7
CFSID252 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-far... 1
CFSID253 Peptide deformylase, mitochondrial Inhibitor Epiroprim Superfa... 9
CFSID254 Reverse transcriptase Inhibitor Ethyl 1-[(1h-benzimidazol-5(6)... 2
CFSID255 Bacterial outer membrane Inhibitor Ethylene Diamine Superfamily 2
CFSID256 Platelet activating factor, putative Inhibitor F-0401 Superfamily 2
CFSID257 Farnesyltransferase beta subunit, putative and Squalene syntha... 5
CFSID258 3-oxo-5-alpha-steroid 4-dehydrogenase 2 and 3-oxo-5-alpha-ster... 10
CFSID259 D(4) dopamine receptor and cAMP-specific 3',5'-cyclic phosphod... 5
CFSID260 Dipeptidyl peptidase 4 Inhibitor Fe 999011 Superfamily 3
CFSID261 Gaba-gated chloride channel Ligand Fipronil Superfamily 3
CFSID262 Neutrophil elastase Inhibitor FK-706 Superfamily 3
CFSID263 ATP-citrate synthase Inhibitor (-)-hydroxycitrate Superfamily 6
CFSID264 Vasopressin V2 receptor and Telomerase reverse transcriptase B... 3
CFSID265 Serine protease Inhibitor Gabexate Superfamily 2
CFSID266 Hepatocyte growth factor and Fibroblast growth factor 1 Binder... 7
CFSID267 Deoxyhypusine synthase Inhibitor GC7 Superfamily 3
CFSID268 Neprilysin Inhibitor Thiorphan Superfamily 5
CFSID269 Farnesyltransferase beta subunit, putative and Protein farnesy... 4
CFSID270 Glucokinase Inhibitor GKA1 Superfamily 4
CFSID271 NF-kappa-B Inhibitor Gliotoxin Family 1
CFSID272 3-phosphoshikimate 1-carboxyvinyltransferase and Probable 3-ph... 3
CFSID273 NF-kappa-B and Protein kinase C zeta type Inhibitor Go6976 Sup... 7
CFSID274 Apoptosis regulator Bcl-2 Inhibitor Gossypol Superfamily 1
CFSID275 5-hydroxytryptamine receptor 1B Ligand GR55562 Superfamily 6
CFSID276 Squalene monooxygenase Inhibitor Green Tea Superfamily 4
CFSID277 S-adenosylmethionine decarboxylase proenzyme Inhibitor Methylg... 1
CFSID278 Gastrin/cholecystokinin type B receptor Ligand GV-150013 Super... 4
CFSID279 Bile acid receptor Ligand GW4064 Superfamily 5
CFSID280 Peroxisome proliferator-activated receptor alpha and Peroxisom... 7
CFSID281 Peroxisome proliferator-activated receptor alpha Ligand GW9578... 3
CFSID282 Dihydroorotate dehydrogenase and Nicotinic acetylcholine recep... 3
CFSID283 Bacterial outer membrane Inhibitor HKI-9924129 Superfamily 7
CFSID284 DNA topoisomerase 2-beta Inhibitor Howiinol A (ghm-10) Superfa... 3
CFSID285 5-hydroxytryptamine receptor 4 Ligand Htf 919 Family 1
CFSID286 Pancreatic alpha-amylase Inhibitor Hydroxycitric Acid Family 1
CFSID287 C-C chemokine receptor type 8 Ligand I-309 Superfamily 5
CFSID288 Neutrophil elastase Inhibitor Ici 200,355 Superfamily 2
CFSID289 Arachidonate 5-lipoxygenase Inhibitor Ici 207968 Superfamily 4
CFSID290 Class II cytokine receptor Ligand IL-10 Superfamily 3
CFSID291 Farnesyl pyrophosphate synthase Inhibitor Incadronate Superfamily 2
CFSID292 Caspase-3 Inhibitor 5-(pyrrolidin-1-ylsulfonyl)indoline-2,3-di... 4
CFSID293 5-hydroxytryptamine receptor 2A and Cholinesterase Binder Supe... 7
CFSID294 Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 3
CFSID295 B-lymphocyte antigen CD20 Inhibitor Iodine-131-tositumomab Sup... 8
CFSID296 NF-kappa-B Inhibitor Isohelenin Superfamily 2
CFSID297 DNA Binder JM216 Family 1
CFSID298 Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 6
CFSID299 Vanilloid receptor 1 Ligand KJM429 Superfamily 2
CFSID300 Alpha-1A adrenergic receptor Ligand KMD-3213 Superfamily 3
CFSID301 Plasmepsin-2 Inhibitor KNI-727 Superfamily 4
CFSID302 Glucose-6-phosphate translocase and Heat shock cognate 71 kDa ... 6
CFSID303 Tyrosine-protein phosphatase non-receptor type 1 Ligand KR6163... 4
CFSID304 DNA topoisomerase 1 Inhibitor KT6006 Superfamily 2
CFSID305 Integrase and Kappa-type opioid receptor Binder Superfamily 2
CFSID306 Geranylgeranyl transferase type-1 subunit beta Inhibitor L-269... 2
CFSID307 Arachidonate 5-lipoxygenase Inhibitor L-652,343 Superfamily 1
CFSID308 Reverse transcriptase Inhibitor L-697,661 Superfamily 3
CFSID309 Integrase and Aldose reductase Binder Superfamily 3
CFSID310 Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 4
CFSID311 D(4) dopamine receptor Ligand L-745,870 Superfamily 9
CFSID312 Suppressor of tumorigenicity 14 protein and Trypsin Binder Sup... 4
CFSID313 Ornithine aminotransferase, mitochondrial and UDP-N-acetylgluc... 3
CFSID314 Ferrochelatase, mitochondrial Inhibitor Lead Acetate Superfamily 2
CFSID315 Glycogen synthase kinase-3 Inhibitor Lithium Chloride Family 1
CFSID316 Mitogen-activated protein kinase kinase kinase 1 Inhibitor LLZ... 1
CFSID317 Vacuolar H+-ATPase Inhibitor Lobatamide A Superfamily 3
CFSID318 Phospholipase A2 Inhibitor LY178002 Superfamily 3
CFSID319 Dihydroorotate dehydrogenase Inhibitor LY214352 Superfamily 5
CFSID320 Transcriptional regulatory protein AlgQ Inhibitor LY266500 Sup... 4
CFSID321 Gastrin/cholecystokinin type B receptor Ligand LY288513 Superf... 1
CFSID322 Metabotropic glutamate receptor 2 Ligand LY341495 Superfamily 3
CFSID323 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3
CFSID324 NF-kappa-B and Coagulation factor X Binder Superfamily 7
CFSID325 Coagulation factor X Inhibitor M55551 Superfamily 4
CFSID326 5-hydroxytryptamine receptor Ligand Mci Superfamily 3
CFSID327 Metabotropic glutamate receptor 4 and Glutamate receptor ionot... 4
CFSID328 Melanocortin receptor 4 Ligand Melanocortin-4 Receptor Antagon... 2
CFSID329 Glucose-6-phosphate 1-dehydrogenase Inhibitor Metazamide Super... 5
CFSID330 Fatty-acid amide hydrolase 1 Inhibitor Methoxy Arachidonyl Flu... 2
CFSID331 23S rRNA Binder Superfamily 2
CFSID332 Cyclin-dependent kinase 1 and Prostaglandin G/H synthase 2 Inh... 2
CFSID333 Serine hydroxymethyltransferase Inhibitor Mimosine Superfamily 2
CFSID334 Glycogen phosphorylase, muscle form and Receptor tyrosine-prot... 5
CFSID335 Farnesyl pyrophosphate synthase Binder Superfamily 2
CFSID336 Alpha-2C adrenergic receptor Ligand MK-912 Superfamily 6
CFSID337 Tryptase and Cholecystokinin receptor type A Binder Superfamily 4
CFSID338 Neutrophil elastase Inhibitor MR-889 Superfamily 4
CFSID339 Adenosine receptor A1 and Adenosine receptor A2a Ligand CGS-15... 3
CFSID340 Calcium-dependent chloride channel-1 Ligand MSI-1956 Superfamily 4
CFSID341 Indoleamine 2,3-dioxygenase 1 and Glucose-6-phosphate transloc... 7
CFSID342 Muscarinic acetylcholine receptor Ligand Muscarine Superfamily 3
CFSID343 Aspartate transcarbamoylase catalytic subunit PyrB Inhibitor N... 2
CFSID344 Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 2
CFSID345 Seprase and Dipeptidyl peptidase 4 Binder Superfamily 6
CFSID346 Tyrosine-protein kinase JAK3 Inhibitor NC1153 Superfamily 2
CFSID347 Farnesyl pyrophosphate synthase Inhibitor NE21650 Superfamily 2
CFSID348 Thyroid hormone receptor Ligand NH-3 Family 1
CFSID349 Thyroid hormone receptor Ligand NH-4 Family 1
CFSID350 Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 1
CFSID351 Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Superf... 3
CFSID352 Chymase and Liver carboxylesterase 1 Binder Superfamily 12
CFSID353 Steryl-sulfatase Inhibitor Nortropinyl-arylsulfonylurea 3 Supe... 2
CFSID354 Glycogen synthase kinase-3 Inhibitor NP12 Superfamily 2
CFSID355 Extracellular calcium-sensing receptor Ligand Nps 568 Superfamily 7
CFSID356 Neuropeptide Y receptor type 1 Ligand NPY-1 Antagonist Superfa... 4
CFSID357 Dihydroorotate dehydrogenase and 5-hydroxytryptamine receptor ... 7
CFSID358 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Olprin... 5
CFSID359 Angiogenin Inhibitor Oltipraz Superfamily 3
CFSID360 Vasopressin V2 receptor and Vasopressin V1a receptor Binder Su... 6
CFSID361 Receptor-type tyrosine-protein phosphatase S Ligand Orthovanad... 1
CFSID362 Amyloid beta A4 protein and Amine oxidase [flavin-containing] ... 6
CFSID363 Cyclin-dependent kinase 5 and Cyclin-dependent kinase 8 Inhibi... 3
CFSID364 Interleukin-6 receptor subunit beta and Inosine-5'-monophospha... 3
CFSID365 Dipeptidyl peptidase 4 Inhibitor P32/98 Family 1
CFSID366 Urokinase-type plasminogen activator Inhibitor PAI-1 Superfamily 5
CFSID367 Urokinase-type plasminogen activator Inhibitor PAI-2 Superfamily 4
CFSID368 Cyclin-dependent kinase 4 and Cyclin-dependent kinase 6 Inhibi... 3
CFSID369 Endothelin-1 receptor Ligand PD156707 Superfamily 6
CFSID370 Mitogen-activated protein kinase kinase kinase 1 and Mitogen-a... 2
CFSID371 Tubulin beta chain and Adenosine receptor A2a Binder Superfamily 8
CFSID372 Protein tyrosine phosphatase Inhibitor Pervanadate Family 1
CFSID373 Aminopeptidase N and Gamma-aminobutyric acid B receptor Binder... 2
CFSID374 Protein kinase C delta type Inhibitor 13-acetylphorbol Superfa... 2
CFSID375 5-hydroxytryptamine receptor 1A and Peptidyl-prolyl cis-trans ... 7
CFSID376 Transcription factor AP-1 Inhibitor PNRI-299 Superfamily 1
CFSID377 Dihydroorotate dehydrogenase Inhibitor Polyporic Acid Superfamily 2
CFSID378 Gp29 Inhibitor Ppa Superfamily 3
CFSID379 Prothrombin Inhibitor Ppack Superfamily 4
CFSID380 Alanine racemase Inhibitor Propionate Superfamily 2
CFSID381 Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 5
CFSID382 DNA topoisomerase 2-beta and DNA topoisomerase 4 subunit A Inh... 2
CFSID383 Uridine 5'-monophosphate synthase Inhibitor Pyrazofurin Family 1
CFSID384 Glucan synthesis regulatory protein Inhibitor Pyridobenzimidaz... 6
CFSID385 NF-kappa-B Inhibitor Pyrrolidine Dithiocarbamate Superfamily 2
CFSID386 Dopamine D2-like receptor Ligand Quinelorane Superfamily 2
CFSID387 Acetyl-CoA carboxylase 1 Inhibitor Quizalofop Superfamily 4
CFSID388 CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor R 8012... 2
CFSID389 Aurora kinase B and Tyrosine-protein kinase Lck Binder Superfa... 13
CFSID390 Arachidonate 5-lipoxygenase Inhibitor R-85355 Superfamily 4
CFSID391 Matrix metalloproteinase-9 Inhibitor Ro 28-2653 Superfamily 5
CFSID392 Muscarinic acetylcholine receptor Ligand Rs 86 Superfamily 2
CFSID393 Type-1 angiotensin II receptor Ligand RTI-76 Superfamily 4
CFSID394 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor RW... 5
CFSID395 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Inhibitor RW... 2
CFSID396 Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Superfamily 7
CFSID397 Glucose-6-phosphate translocase Inhibitor S 3025 Superfamily 2
CFSID398 CAMP-phosphodiesterase Inhibitor S(-)enantiomer Of 3-(3-hydrox... 2
CFSID399 Neuropeptide Y receptor type 1 and Neuropeptide Y receptor typ... 1
CFSID400 Glucose-6-phosphate translocase Inhibitor S-4048 Family 1
CFSID401 Prostaglandin D2 receptor Ligand S-5751 Superfamily 2
CFSID402 Coronavirus main proteinase Inhibitor Sabadinine Superfamily 2
CFSID403 Muscarinic acetylcholine receptor M1 Ligand Sabcomeline Superf... 4
CFSID404 Alpha-2 adrenergic receptor Ligand Saline Family 1
CFSID405 D(2) dopamine receptor and Interleukin-1 receptor type 1 Binde... 13
CFSID406 5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5
CFSID407 5-hydroxytryptamine receptor 6 Ligand Sb 258585 Superfamily 2
CFSID408 5-hydroxytryptamine receptor 7 and D(2) dopamine receptor Liga... 2
CFSID409 C-X-C chemokine receptor type 2 Ligand Sb 272844 Superfamily 2
CFSID410 Coagulation factor X Inhibitor SC-83157 Superfamily 2
CFSID411 Gamma-aminobutyric acid B receptor Ligand Sch 50911 Superfamily 3
CFSID412 5-hydroxytryptamine receptor 1A Ligand Sdz 216-525 Superfamily 5
CFSID413 NMDA receptor Ligand Selfotel Superfamily 4
CFSID414 Integrin beta-3 and Integrin alpha-V Binder Superfamily 4
CFSID415 Neuronal acetylcholine receptor subunit beta-4 Ligand SIB-1553... 2
CFSID416 Interleukin-4 Inhibitor SIL-4R Superfamily 2
CFSID417 Coagulation factor X Inhibitor SK509 Superfamily 3
CFSID418 5-hydroxytryptamine receptor 4 Ligand Sl65.0155 Superfamily 3
CFSID419 5-hydroxytryptamine receptor and Muscarinic acetylcholine rece... 8
CFSID420 Sodium- and chloride-dependent GABA transporter 3 Inhibitor SN... 7
CFSID421 Protein tyrosine phosphatase short form Inhibitor Sodium Ortho... 1
CFSID422 Somatostatin Inhibitor Somatoprim Superfamily 1
CFSID423 DNA topoisomerase 2-beta and Telomerase reverse transcriptase ... 4
CFSID424 Lethal factor and Choline-phosphate cytidylyltransferase Binde... 3
CFSID425 Matrix protein 2 Inhibitor Spiro[pyrrolidine-2,2-adamantane] F... 1
CFSID426 Aldose reductase Inhibitor SPR-210 Superfamily 5
CFSID427 Liver carboxylesterase 1 and Voltage-dependent L-type calcium ... 7
CFSID428 Vasopressin V1a receptor Ligand Sr 49059 Superfamily 2
CFSID429 Cannabinoid receptor 2 Ligand SR144528 Superfamily 7
CFSID430 Substance-P receptor Ligand SSR240600 Superfamily 6
CFSID431 Fibroblast growth factor receptor 3 Ligand SU10991 Superfamily 3
CFSID432 Fibroblast growth factor receptor Ligand SU5403 Superfamily 4
CFSID433 Cyclin-dependent kinase 1 and Cyclin-dependent kinase 2 Inhibi... 3
CFSID434 Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfamily 3
CFSID435 Herpes simplex virus type 1 thymidine kinase and ATP-sensitive... 5
CFSID436 5-hydroxytryptamine receptor 1A Ligand Sun N4057 Superfamily 6
CFSID437 Oxysterols receptor LXR Ligand T0901317 Superfamily 4
CFSID438 Nonstructural protein 5b Inhibitor T-1106 Superfamily 2
CFSID439 5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 6
CFSID440 Platelet activating factor, putative Inhibitor TCV-309 Superfa... 2
CFSID441 D-alanyl-D-alanine carboxypeptidase Inhibitor TD-1792 Family 1
CFSID442 5-hydroxytryptamine receptor 4 Ligand TD-5108 Superfamily 4
CFSID443 Neutrophil elastase Inhibitor TEI-8362 Family 1
CFSID444 Squalene monooxygenase Inhibitor Tellurium Family 1
CFSID445 Potassium channel Ligand Tetraethylammonium (tea) Superfamily 5
CFSID446 Peroxisome proliferator-activated receptor gamma Ligand Thiazo... 3
CFSID447 Squalene monooxygenase Inhibitor Thiocarbamate Family 1
CFSID448 Poly [ADP-ribose] polymerase 1 Inhibitor TI4 Superfamily 4
CFSID449 Heme oxygenase 1 and Prostaglandin G/H synthase 1 Binder Super... 3
CFSID450 Delta-type opioid receptor Ligand Tip Family 1
CFSID451 Mu-type opioid receptor and Delta-type opioid receptor Binder ... 8
CFSID452 Coagulation factor X Inhibitor Tissue Factor Pathway Inhibitor... 3
CFSID453 Gp29 Inhibitor Tmpyp4 Superfamily 10
CFSID454 Methionine aminopeptidase 2 Inhibitor TNP-470 Superfamily 4
CFSID455 Ribonucleoside-diphosphate reductase large subunit Inhibitor T... 2
CFSID456 Dihydroorotate dehydrogenase Inhibitor Triazine Superfamily 2
CFSID457 Histone deacetylase 6 Inhibitor Tubacin Superfamily 4
CFSID458 Histamine H3 receptor Binder Superfamily 3
CFSID459 Neutrophil elastase Inhibitor Ulinastatin Superfamily 3
CFSID460 Integrase Inhibitor V-165 Superfamily 1
CFSID461 Sarcoplasmic/endoplasmic reticulum calcium ATPase Inhibitor Va... 1
CFSID462 Vasopressin V2 receptor Ligand VP-343 Superfamily 3
CFSID463 Peptide deformylase, mitochondrial Inhibitor VRC3375 Superfamily 3
CFSID464 Fatty-acid amide hydrolase 1 and Inosine-5'-monophosphate dehy... 3
CFSID465 Muscarinic acetylcholine receptor M1 Ligand WAY-132983 Superfa... 3
CFSID466 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1
CFSID467 Tubulin Inhibitor WR85915 Superfamily 4
CFSID468 Cytochrome P450 3A4 and Tumor necrosis factor Binder Superfamily 5
CFSID469 Chymase Inhibitor Y-40613 Superfamily 9
CFSID470 Soluble guanylate cyclase Inhibitor YC-1 Superfamily 3
CFSID471 Coagulation factor X Inhibitor YM60828 Superfamily 3
CFSID472 Glutamate receptor AMPA subtype Ligand YM872 Superfamily 4
CFSID473 Coagulation factor X Inhibitor YM-96765 Family 1
CFSID474 Caspase-1 Inhibitor Yvad Superfamily 3
CFSID475 Beta-3 adrenergic receptor Ligand ZD7114 Superfamily 6
CFSID476 Caspase-9 Inhibitor Z-lehd-fmk Superfamily 3
CFSID477 Arachidonate 5-lipoxygenase Inhibitor ZM-230487 Superfamily 6
CFSID478 CDP-diacylglycerol--inositol 3-phosphatidyltransferase Inhibit... 1
CFSID479 Acid-sensing ion channel 1 Ligand Pctx1 Superfamily 1
CFSID480 Sodium channel protein type 10 subunit alpha Ligand A-803467 S... 5
CFSID481 Voltage-gated sodium channel Ligand SB-221420-A Superfamily 4
CFSID482 Carbonic anhydrase 1 and Carbonic anhydrase 2 Binder Superfami... 3
CFSID483 Neutrophil elastase Inhibitor ED1 Superfamily 3
CFSID484 Cytochrome P450 11B1, mitochondrial Inhibitor 3-meso2-dde Supe... 5
CFSID485 Glutamate carboxypeptidase 2 and Beta-lactamase Binder Superfa... 7
CFSID486 Ryanodine receptor 2 Ligand Glycylryanodine Superfamily 2
CFSID487 Equilibrative nucleoside/nucleobase transporter Inhibitor Nitr... 4
CFSID488 3-oxoacyl-[acyl-carrier-protein] synthase II Inhibitor Platens... 1
CFSID489 Histamine H3 receptor Ligand A-317920 Superfamily 3
CFSID490 Histamine H3 receptor Ligand A-331440 Superfamily 5
CFSID491 Cholecystokinin receptor type A Ligand Asperlicin Superfamily 2
CFSID492 Histone deacetylase Inhibitor Azelaic Bishydroxamic Acid Super... 2
CFSID493 Histone deacetylase Inhibitor CG-1521 Superfamily 2
CFSID494 Histamine H3 receptor and Alpha-2A adrenergic receptor Binder ... 13
CFSID495 Poly [ADP-ribose] polymerase 1 Inhibitor DR2313 Superfamily 3
CFSID496 RAC-gamma serine/threonine-protein kinase Inhibitor GSK690693 ... 4
CFSID497 Histamine H3 receptor and Sodium-dependent serotonin transport... 3
CFSID498 RAC-gamma serine/threonine-protein kinase Inhibitor Lactoquino... 3
CFSID499 Multidrug resistance protein Inhibitor MM36 Superfamily 4
CFSID500 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5
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Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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