CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD1002
Family Name Reverse transcriptase Inhibitor Sorivudine Family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00116578 Functional Category Approved Drug
Superfamily Reverse transcriptase Inhibitor Sorivudine Superfamily
Class Class 408

Cousin Family NamesSeedsMembers
HBV polymerase inhibitor thymidine nucleoside analog Telbivudi... 12 128
HIV reverse transcriptase inhibitor thymidine nucleoside analo... 4 14
Thymidylate synthase inhibitor thymidine nucleoside analog Flo... 8 48
P2Y purinoceptor 2 Inhibitor Diquafosol Family 2 44
Uridine Triacetate family 2 8
DNA polymerase Inhibitor 5-propenyl-arabinofuranosyluracil 5'-... 1 1
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyroph... 3 24
Uridine 5'-monophosphate synthase Inhibitor 5-fluoro-6-iodo-um... 3 2
P2Y purinoceptor 6 inhibitor [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(... 1 3
P2Y purinoceptor 14 and P2Y purinoceptor 6 inhibitor N,N-dieth... 3 17
Reverse transcriptase/RNaseH inhibitor 6-amino-3-[(3S,4S,5R)-5... 2 1
Reverse transcriptase/RNaseH inhibitor ddUTP family 1 0
P2Y purinoceptor 6 and P2Y purinoceptor 2 inhibitor [[[[(2R,3S... 1 0
Pyrimidine Nucleotides Metabolite Orotidylic acid Family 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00116578 DNAP001431 Approved Drug Sorivudine
CFAMM00116576 DCL001019 Clinical Trial Drug TGBA01AD
CFAMM00116583 DNCL002755 Clinical Trial Drug RP101

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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