CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD1073
Family Name Chromomycin A3 family
No. of Seeds 7 No. of Other Members 14
Family Centroid CFAMM00125110 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Chromomycin A3 Superfamily
Class Class 47

Cousin Family NamesSeedsMembers
DNA binder anthracycline analog Doxorubicin family 9 32
DNA topoisomerase 2-beta Inhibitor Etoposide Family 3 29
Heat shock protein 90, putative Inhibitor Cromoglicate Family 14 2827
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Aldehyde oxidase Inhibitor Isovanillin Family 6 429
Hidrosmin family 14 61
Ipriflavone family 62 2480
Rotenone family 16 107
Danthron family 11 141
taste receptor Ligand Cynarin Family 6 124
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Glucose-6-phosphate translocase Inhibitor Kodaistatin A Family 1 0
Endothelin-1 receptor Ligand PD156707 Family 41 211
Protein kinase C alpha type and Protein kinase C beta type Inh... 7 1
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
Phospholipase A2 Inhibitor 3,9-dihydroxy-2,10-diprenylpterocap... 9 25
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Tyrosine-protein phosphatase non-receptor type 1 Ligand Phelli... 1 1
Protein kinase C alpha type and Protein kinase C beta type Inh... 2 1
Protein kinase C alpha type Inhibitor Acetoside Family 5 39
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Squalene monooxygenase Inhibitor Octyl_gallate Family 5 5
Indoleamine 2,3-dioxygenase 1 Inhibitor 2-hydroxygarvin A Family 2 2
Voltage-dependent N-type calcium channel subunit alpha-1B Liga... 1 6
Heat shock cognate 71 kDa protein Inhibitor NSC-119913 Family 2 1
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Androgen receptor Ligand Palodesangren E Family 12 43
CGMP-dependent protein kinase Inhibitor Tenellone A Family 1 7
72 kDa type IV collagenase Inhibitor Lithospermic Acid Family 1 0
Liver carboxylesterase 1 Inhibitor 2-methoxy-3,4-methylenediox... 4 26
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Eukaryotic initiation factor 4A-I inhibitor methyl (1R,2R,3S,3... 12 1
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 1 0
Calmodulin inhibitor CHEMBL2408940 family 1 0
Survival motor neuron protein and Prelamin-A/C inhibitor CHEMB... 2 32
Aldehyde dehydrogenase, cytosolic 1 and Aldehyde dehydrogenase... 2 0
72 kDa type IV collagenase inhibitor [(2S,3S,4R)-4-(4,5-dihydr... 1 0
Sugar Acids and Derivatives Metabolite 3-Methoxy-4-hydroxyphen... 1 6
Putative NP ZINC02398203 Family 1 0
NP 2-((3-(3,4-dihydro-2h-benzo[b][1,4]dioxepin-7-yl)-6-ethyl-4... 10 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00125110 DNAP001662 Approved Drug Chromomycin a3
CFAMM00124953 DNAP001632 Approved Drug Sennoside b
CFAMM00124952 DNAP001633 Approved Drug Sennoside a
CFAMM00125090 DNAP001652 Approved Drug Plicamycin
CFAMM00124966 DNC013642 Investigative Drug GERANIIN
CFAMM00124965 DNC013645 Investigative Drug mallotusinic acid
CFAMM00125190 DNC000582 Investigative Drug Durhamycin A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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