CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD1087
Family Name Adenosine receptor A2a Ligand Regadenoson Family
No. of Seeds 10 No. of Other Members 22
Family Centroid CFAMM00125384 Functional Category Approved Drug
Superfamily Adenosine receptor A2a Ligand Regadenoson Superfamily
Class Class 793

Cousin Family NamesSeedsMembers
Adenosine receptor A3 ligand purine nucleoside Adenosine Family 47 847
Adenosine receptor A1 and Adenosine receptor A2a Ligand GW-328... 26 94
Adenosine receptor A3 and Adenosine receptor A1 ligand (2R,3R,... 1 5
Adenosine receptor A1 ligand 1-[6-(4-bicyclo[2.2.1]heptanylami... 3 0
Adenosine receptor A2a and Adenosine receptor A2b ligand (3R,4... 7 3


External ID

Functional Category

Molecule Name

CFAMM00125384 DNAP001677 Approved Drug Regadenoson
CFAMM00125376 CHEMBL232100 Bioactive 1-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[[(2R)-oxolan-2-yl]amino]purin-2-yl]-N-ethylpyrazole-4-carboxamide
CFAMM00125394 CHEMBL393916 Bioactive 1-[6-(cyclohexylamino)-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-methylpyrazole-4-carboxamide
CFAMM00125397 CHEMBL400034 Bioactive SureCN13800665
CFAMM00125374 CHEMBL398588 Bioactive ethyl 1-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[[(2R)-oxolan-2-yl]amino]purin-2-yl]pyrazole-4-carboxylate
CFAMM00125392 CHEMBL232482 Bioactive SureCN13800671
CFAMM00125373 CHEMBL392958 Bioactive SureCN13800664
CFAMM00125400 CHEMBL391208 Bioactive 1-[6-(cyclopentylamino)-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-2-yl]-N-ethylpyrazole-4-carboxamide
CFAMM00125370 CHEMBL232313 Bioactive 1-[9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-[[(2R)-oxolan-2-yl]amino]purin-2-yl]-N-propylpyrazole-4-carboxamide
CFAMM00125377 CHEMBL232670 Bioactive SureCN13800681

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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