CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD1094
Family Name Cystic fibrosis transmembrane conductance regulator Inhibitor Ivacaftor Family
No. of Seeds 2 No. of Other Members 9
Family Centroid CFAMM00125892 Functional Category Approved Drug with Natural Product
Superfamily Cystic fibrosis transmembrane conductance regulator Inhibitor Ivacaftor Superfamily
Class Class 798

Cousin Family NamesSeedsMembers
Cruzipain Inhibitor 1-(3-methoxy-benzyl)-5-methyl-1h-indole-2,... 2 11
Epidermal growth factor receptor Ligand 4-acrylamido-n-(3-brom... 2 20
Estradiol 17-beta-dehydrogenase 1 Inhibitor 2-hydroxy-n,6-bis(... 2 7
Cannabinoid receptor 2 ligand AGN-PC-080VZH family 3 33
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 13 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 6 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand CHEMB... 2 2
Kinesin-like protein KIF11 inhibitor 3-benzyl-2-(3-hydroxyphen... 2 1
DNA-dependent protein kinase catalytic subunit and DNA-(apurin... 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00125892 DNAP001684 Approved Drug Ivacaftor
CFAMM00125884 CHEMBL1215918 Bioactive AGN-PC-080W33

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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