CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD1102
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Avanafil Family
No. of Seeds 3 No. of Other Members 16
Family Centroid CFAMM00126250 Functional Category Approved Drug
Superfamily cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Avanafil Superfamily
Class Class 6

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 17 3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 28
Adenosine receptor A3 ligand AGN-PC-07N4XZ family 4 11
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 2 0
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 3 0
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17i ... 3 6
Nitric oxide synthase, inducible inhibitor SureCN5194847 family 24 48
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
Nitric oxide synthase, inducible inhibitor N-(1,3-benzodioxol-... 11 1
Adenosine receptor A1 ligand ethyl 1-(2-chloro-2-phenylethyl)-... 5 1
Cannabinoid receptor 1 ligand AGN-PC-07CO0E family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00126250 DNAP001693 Approved Drug Avanafil
CFAMM00126242 CHEMBL269079 Bioactive SureCN7962059
CFAMM00126246 CHEMBL7868 Bioactive SureCN7005158

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27269 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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