CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD118
Family Name SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand Tolbutamide Family
No. of Seeds 3 No. of Other Members 35
Family Centroid CFAMM00022362 Functional Category Approved Drug
Superfamily SUR1-type K(ATP) channel and SUR2-type K(ATP) channel Ligand Tolbutamide Superfamily
Class Class 109

Cousin Family NamesSeedsMembers
ATP-sensitive inward rectifier potassium channel 10 Ligand Ace... 2 64
Thymidylate synthase Inhibitor N-[tosyl-d-prolinyl]amino-ethan... 1 10
Carbonic anhydrase 2 Inhibitor N-benzyl-4-sulfamoyl-benzamide ... 12 44
Carbonic anhydrase 2 Inhibitor 4-(2-aminoethyl)benzenesulfonam... 3 30
Alpha-2A adrenergic receptor Ligand SK&F-29661 Family 3 42
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-acet... 6 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 2-valp... 8 5
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-(2-p... 6 19
5-hydroxytryptamine receptor 6 ligand N-[[(1R)-6-(benzenesulfo... 8 2
Pol polyprotein inhibitor Lysine Sulfonamide 11c family 3 73
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor [2-(4-... 2 0
Carbonic anhydrase 12 and Carbonic anhydrase 2 inhibitor AGN-P... 5 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[2-[... 10 5
Bifunctional epoxide hydrolase 2 inhibitor 1-(2-bromophenyl)su... 2 5
Bifunctional epoxide hydrolase 2 inhibitor N-cycloheptyl-1-(2,... 7 8
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 1
Fructose-1,6-bisphosphatase 1 inhibitor AGN-PC-04URJO family 2 0
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 6 4
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor 2-[car... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00022362 DAP000136 Approved Drug Tolbutamide
CFAMM00022310 DNC009516 Investigative Drug 1-(2-mercaptoethyl)-3-(m-tolylsulfonyl)urea
CFAMM00022327 DNC003351 Investigative Drug N-{2-[4-(AMINOSULFONYL)PHENYL]ETHYL}ACETAMIDE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21794 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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