CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD129
Family Name Acetylcholinesterase Inhibitor Rivastigmine Family
No. of Seeds 2 No. of Other Members 59
Family Centroid CFAMM00023216 Functional Category Approved Drug
Superfamily Acetylcholinesterase Inhibitor Rivastigmine Superfamily
Class Class 120

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Alpha-1 adrenergic receptor ligand Dextroamphetamine derivativ... 5 29
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Substance-P receptor Ligand Ezlopitant Family 10 207
D(3) dopamine receptor Ligand U-99194A Family 7 33
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
Histamine H3 receptor Ligand A-331440 Family 6 7
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
Fatty-acid amide hydrolase 1 Inhibitor N-butylcarbamic Acid Bi... 9 31
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phen... 3 0
Fatty-acid amide hydrolase 1 Inhibitor 8-phenyloctylcarbamic A... 12 1
Fatty-acid amide hydrolase 1 Inhibitor Adamant-1-ylcarbamic Ac... 1 0
Fatty-acid amide hydrolase 1 Inhibitor 3-(4,5-dihydrooxazol-2-... 6 11
Acetylcholinesterase inhibitor [(3aR,8bS)-3,8b-dimethyl-1,2,3a... 1 27
Cathepsin K inhibitor [1-(3-methoxyphenyl)-2-methylpropan-2-yl... 2 10
Shiga toxin 1 variant B subunit and Shiga toxin 1 variant A su... 1 117
5-hydroxytryptamine receptor 1A ligand [(1S,2R)-8-methoxy-2-(p... 4 0
Cholinesterase and Acetylcholinesterase inhibitor AGN-PC-009M2... 1 6
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 7 4
Chymase inhibitor 1,3-bis[(3-methoxyphenyl)methyl]-1,3-diazeti... 3 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-006SR... 1 2
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-074BF6 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00023216 DAP000149 Approved Drug Rivastigmine
CFAMM00023237 CHEMBL554452 Bioactive AGN-PC-07C0GR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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