CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD133
Family Name 14-alpha sterol demethylase inhibitor imidazole derivative Miconazole Family
No. of Seeds 6 No. of Other Members 59
Family Centroid CFAMM00024056 Functional Category Approved Drug with Human Metabolite
Superfamily 14-alpha sterol demethylase inhibitor imidazole derivative Miconazole Tioconazole Superfamily
Class Class 123

Cousin Family NamesSeedsMembers
14-alpha sterol demethylase Inhibitor Terconazole Family 4 46
14-alpha sterol demethylase Inhibitor Butoconazole Family 2 53
14-alpha sterol demethylase inhibitor imidazole derivative Ti... 2 2
3-oxoacyl-[acyl-carrier-protein] synthase 3 inhibitor 1-(2-met... 3 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 1
Heme oxygenase 1 and Heme oxygenase 2 inhibitor 1-imidazol-1-y... 2 2
ATP synthase subunit beta, mitochondrial and ATP synthase subu... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Aromatase inhibitor SureCN11531968 family 1 3
Heme oxygenase 1 and Heme oxygenase 2 inhibitor imidazole-diox... 2 15
Heme oxygenase 1 inhibitor 1-[[(2R,4R)-2-[2-(4-chlorophenyl)et... 4 13


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00024052 DAP001204 Approved Drug Oxiconazole
CFAMM00024069 DAP001269 Approved Drug Econazole
CFAMM00024056 DAP000154 Approved Drug Miconazole
CFAMM00024030 CHEMBL368348 Bioactive (R)-MICONAZOLE
CFAMM00024032 DNC004441 Investigative Drug ISOCONAZOLE
CFAMM00024043 DNC011354 Investigative Drug ECONAZOLE NITRATE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21768 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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