CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD137
Family Name DNA topoisomerase 2-beta Inhibitor Gatifloxacin Family
No. of Seeds 9 No. of Other Members 52
Family Centroid CFAMM00024502 Functional Category Approved Drug
Superfamily DNA topoisomerase 2-beta Inhibitor Gatifloxacin Superfamily
Class Class 126

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor MCB-3837 Family 1 0
DNA gyrase subunit A Inhibitor ACH-702 Family 1 2
Glycogen synthase kinase-3 beta inhibitor CHEMBL1940907 family 2 21
Glycogen synthase kinase-3 beta inhibitor CHEMBL1940979 family 1 0
Muscarinic acetylcholine receptor M1 ligand 5,8-difluoro-1-[(4... 1 5
6,8-dimethoxy-4-oxo-1H-quinoline-3-carboxylate NP ZINC00117350... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00024453 DAP001458 Approved Drug Balofloxacin
CFAMM00024502 DAP000159 Approved Drug Gatifloxacin
CFAMM00024473 DAP000160 Approved Drug Levofloxacin
CFAMM00024501 DAP000158 Approved Drug Moxifloxacin
CFAMM00024478 DAP000655 Approved Drug Ofloxacin
CFAMM00024504 DNCL002961 Clinical Trial Drug Nemonoxacin
CFAMM00024457 DNCL003528 Clinical Trial Drug Avarofloxacin
CFAMM00024461 DNC003859 Investigative Drug A-62176
CFAMM00024511 DNC001149 Investigative Drug Premafloxacin

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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