CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA topoisomerase 2-beta and DNA topoisomerase 2-beta inhibitor fluoroquinolone Ciprofloxacin Family
No. of Seeds 9 No. of Other Members 181
Family Centroid CFAMM00024556 Functional Category Approved Drug with Human Metabolite
Superfamily DNA topoisomerase inhibitor fluoroquinolone Superfamily
Class Class 127

Cousin Family NamesSeedsMembers
DNA topoisomerase 2-beta inhibitor fluoroquinolone Besifloxaci... 1 11
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 17 50
DNA polymerase III PolC-type inhibitor SureCN11967746 family 3 17
Glycogen synthase kinase-3 beta inhibitor 5-amino-1-cyclopropy... 3 14
Muscarinic acetylcholine receptor M1 ligand 5-fluoro-4-oxo-1-[... 1 5
5-hydroxytryptamine receptor 6 ligand AGN-PC-00ADLV family 1 0
Signal transducer and activator of transcription 3 inhibitor A... 2 1


External ID

Functional Category

Molecule Name

CFAMM00024700 DAP000653 Approved Drug Lomefloxacin
CFAMM00024645 DAP001001 Approved Drug Pefloxacin
CFAMM00024601 DAP001465 Approved Drug Ciprofloxacin XR
CFAMM00024614 DAP000928 Approved Drug Fleroxacin
CFAMM00024556 DAP000190 Approved Drug Ciprofloxacin
CFAMM00024642 DAP001005 Approved Drug Grepafloxacin
CFAMM00024704 DAP000654 Approved Drug Norfloxacin
CFAMM00024594 DAP000161 Approved Drug Sparfloxacin
CFAMM00024640 DNC000199 Investigative Drug Amifloxacin

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



24536 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543