CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Gamma-aminobutyric acid uptake Inhibitor Tiagabine Family
No. of Seeds 1 No. of Other Members 16
Family Centroid CFAMM00024799 Functional Category Approved Drug
Superfamily Gamma-aminobutyric acid uptake Inhibitor Tiagabine Superfamily
Class Class 130

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 5 32
Sodium-dependent serotonin transporter and Sodium-dependent do... 3 2
Sodium-dependent serotonin transporter and Sodium-dependent do... 6 3
Transporter and Sodium-dependent serotonin transporter inhibit... 2 0
Sodium- and chloride-dependent GABA transporter 1 inhibitor (3... 4 3


External ID

Functional Category

Molecule Name

CFAMM00024799 DAP000164 Approved Drug Tiagabine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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