CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name DNA polymerase/reverse transcriptase and Reverse transcriptase Inhibitor Emtricitabine Family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00025023 Functional Category Approved Drug with Human Metabolite
Superfamily DNA polymerase/reverse transcriptase and Reverse transcriptase Inhibitor Emtricitabine Superfamily
Class Class 133

Cousin Family NamesSeedsMembers
Reverse transcriptase/RNaseH inhibitor 3TC-TP family 3 0


External ID

Functional Category

Molecule Name

CFAMM00025032 DAP000167 Approved Drug Lamivudine
CFAMM00025039 DNAP001708 Approved Drug Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate
CFAMM00025023 DAP001084 Approved Drug Emtricitabine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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