CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name NMDA receptor Ligand L-glutamic Acid Family
No. of Seeds 6 No. of Other Members 32
Family Centroid CFAMM00002599 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily NMDA receptor Ligand L-glutamic Acid Superfamily
Class Class 15

Cousin Family NamesSeedsMembers
Plasminogen Inhibitor Aminocaproic Acid Family 4 37
4-aminobutyrate aminotransferase, mitochondrial Inhibitor L-al... 3 23
Carbamoyl-phosphate synthase [ammonia], mitochondrial Inhibito... 5 13
Metabotropic glutamate receptor 2 Ligand Dcg Iv Family 6 9
C-X-C motif chemokine 10 Inhibitor N-methylleucine Family 1 11
Metabotropic glutamate receptor 8 Ligand 2-amino-4-phosphono-b... 5 13
Sodium- and chloride-dependent GABA transporter 1 Inhibitor 2,... 1 3
Glutamate receptor ionotropic, kainate 1 Ligand (2s,4r)-4-(3-m... 2 7
Bloom syndrome protein and Prelamin-A/C inhibitor trans-Azetid... 1 6
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 1
Glutamyl aminopeptidase and Aminopeptidase N inhibitor (4S)-4-... 1 0
Amino Acids and Derivatives Metabolite Saccharopine Family 2 1


External ID

Functional Category

Molecule Name

CFAMM00002599 DAP000015 Approved Drug L-Glutamic Acid
CFAMM00002581 DNC002459 Investigative Drug Gamma-Carboxy-Glutamic Acid
CFAMM00002572 DNC013913 Investigative Drug 2S,4R-4-METHYLGLUTAMATE
CFAMM00002587 DNC004097 Investigative Drug (4R)-4-ammoniopentanoate
CFAMM00002585 DNC004099 Investigative Drug (4S)-4-ammoniopentanoate
CFAMM00002558 DNC004364 Investigative Drug GLUTAMATE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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