Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.
Cousin Family Names Seeds Members Serotonin re-uptake inhibitor tetralin derivative Sertraline f... 12 118 5-hydroxytryptamine 2 receptor Ligand tricyclic antidepressant... 29 680 Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140 Amine oxidase [flavin-containing] B Inhibitor Selegiline Family 6 26 Nuclear receptor subfamily 1 group I member 3 ligand piperazin... 3 82 Muscarinic acetylcholine receptor M3 Ligand Diphemanil Methyls... 22 45 Dopamine reuptake Inhibitor Brasofensine Family 1 0 Dopamine reuptake and Noradrenergic re-uptake Inhibitor Dov 21... 16 89 5-hydroxytryptamine receptor 2C Ligand Lorcaserin Family 8 38 Tumor necrosis factor Inhibitor Talactoferrin Alfa Family 26 131 Zicronapine family 43 62 D(2) dopamine receptor and D(3) dopamine receptor Ligand (-)-3... 15 19 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 5-(4-chloro-... 3 7 Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 6 7 Dipeptidyl peptidase 4 Inhibitor 2-(2-chlorophenyl)-2-morpholi... 2 34 Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 24 Histamine H3 receptor Ligand 1-[2-(2,4,6-trimethyl-phenyl)-eth... 9 15 Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71 Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2 Sodium-dependent dopamine transporter and Sodium-dependent ser... 5 1 Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2 Sigma non-opioid intracellular receptor 1 ligand NCI60_038428 ... 5 9 Sodium-dependent serotonin transporter and Sodium-dependent no... 12 0 Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 18 4 Pyruvate kinase PKM and Huntingtin inhibitor CHEMBL1455935 family 1 3 Sigma non-opioid intracellular receptor 1 ligand 1-[2-(3,4-dic... 8 4 Sodium-dependent serotonin transporter and Sodium-dependent do... 5 6 Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 2 Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0 Transporter and Sodium-dependent dopamine transporter inhibito... 3 0 Transporter and Sodium-dependent serotonin transporter inhibit... 4 8 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and Sigma no... 1 4 Sodium-dependent dopamine transporter inhibitor N-[[(1S,3S,4R,... 1 0 Sodium-dependent serotonin transporter and Sodium-dependent no... 3 4 Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 12 Sodium-dependent dopamine transporter and Sodium-dependent nor... 3 1 5-hydroxytryptamine receptor 1A ligand SureCN8901985 family 1 0 Histamine H3 receptor ligand (3aR,6aR)-2-propan-2-yl-4-[4-(2-p... 6 5 D(1A) dopamine receptor and D(2) dopamine receptor ligand A314... 3 1 Sigma non-opioid intracellular receptor 1 ligand NCI60_039912 ... 2 0 D(2) dopamine receptor and D(1A) dopamine receptor ligand AGN-... 2 1 C-C chemokine receptor type 5 ligand 1-[[(3S,4S)-1-(cyclohexyl... 1 0 Sodium-dependent dopamine transporter and Muscarinic acetylcho... 2 6 Sodium-dependent dopamine transporter and Sodium-dependent nor... 1 0 Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 0 Kinesin-like protein KIF11 inhibitor 4-(4-chlorophenyl)-4,4-di... 1 2 Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 1 D(1A) dopamine receptor and D(3) dopamine receptor ligand (2S,... 5 5 Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAM Mol ID
External ID
Functional Category
Molecule Name
CFAMM00026860
CHEMBL322067
Bioactive
AC1Q3O5O CFAMM00026936
CHEMBL219335
Bioactive
AGN-PC-00ACMW CFAMM00026929
CHEMBL103829
Bioactive
SureCN3827721 CFAMM00026979
CHEMBL1813317
Bioactive
(3aR,7aS)-7a-(3,4-dichlorophenyl)-2-ethyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026943
CHEMBL534501
Bioactive
(1R,2S,9aR)-1-(3,4-dichlorophenyl)-2-ethyl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine;hydrochloride CFAMM00026956
CHEMBL494624
Bioactive
(1S,3S,4S,5R)-3-(4-chlorophenyl)-4-(2,2-dibromoethenyl)-8-methyl-8-azabicyclo[3.2.1]octane;hydrochloride CFAMM00026879
CHEMBL1683872
Bioactive
AGN-PC-09QKF5 CFAMM00026886
CHEMBL300647
Bioactive
A31472 CFAMM00026949
CHEMBL316988
Bioactive
SureCN6684370 CFAMM00026915
CHEMBL143360
Bioactive
BD-1047 CFAMM00026928
CHEMBL173861
Bioactive
AC1O3H6V CFAMM00026865
CHEMBL1683880
Bioactive
AGN-PC-09QGY5 CFAMM00026878
CHEMBL1683873
Bioactive
AGN-PC-09QKF6 CFAMM00026942
CHEMBL373710
Bioactive
2-[1-(4-chlorophenyl)-4-methylpentyl]piperidine CFAMM00026871
CHEMBL1683889
Bioactive
AGN-PC-09QGYM CFAMM00026921
CHEMBL556365
Bioactive
(1R,9aR)-1-(3,4-dichlorophenyl)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine;hydrochloride CFAMM00026948
CHEMBL1743803
Bioactive
Mcn 5707 CFAMM00026977
CHEMBL45491
Bioactive
A-23887 CFAMM00026914
CHEMBL494814
Bioactive
(1S,3S,4R,5R)-3-(4-chlorophenyl)-8-methyl-4-(2-phenylethynyl)-8-azabicyclo[3.2.1]octane;hydrochloride CFAMM00026940
CHEMBL32797
Bioactive
(6R,10bS)-6-(4-chlorophenyl)-10b-methyl-2,3,5,6-tetrahydro-1H-pyrrolo[2,1-a]isoquinoline CFAMM00026983
CHEMBL220247
Bioactive
AGN-PC-00ACMV CFAMM00026933
CHEMBL2321996
Bioactive
(3R)-3-(3,4-dichlorophenyl)-1-methyl-2,3,4,7-tetrahydroazepine CFAMM00026976
CHEMBL219653
Bioactive
2-[1-(4-chlorophenyl)-2-cyclopentylethyl]piperidine CFAMM00026899
CHEMBL1684044
Bioactive
AGN-PC-04SSM2 CFAMM00026913
CHEMBL449047
Bioactive
(1S,3S,4R,5R)-3-(4-chlorophenyl)-4-ethynyl-8-methyl-8-azabicyclo[3.2.1]octane;hydrochloride CFAMM00026926
CHEMBL1813487
Bioactive
(3aS,7aS)-7a-[(3,4-dichlorophenyl)methyl]-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026891
CHEMBL558395
Bioactive
(1R,2R,9aR)-1-(3,4-dichlorophenyl)-2-ethyl-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine;hydrochloride CFAMM00026982
CHEMBL1813314
Bioactive
(3aS,7aR)-7a-(3,4-dichlorophenyl)-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026996
CHEMBL1743790
Bioactive
(6S,10bR)-6-(3-chlorophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline;hydrobromide CFAMM00026882
CHEMBL1683877
Bioactive
AGN-PC-09QIPA CFAMM00026959
CHEMBL1813484
Bioactive
(3aR,6aS)-3a-(3,4-dichlorophenyl)-2-methyl-1,3,4,5,6,6a-hexahydrocyclopenta[c]pyrrole CFAMM00026975
CHEMBL1172902
Bioactive
SureCN13039295 CFAMM00026938
CHEMBL387117
Bioactive
2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1-methylpiperidine CFAMM00026890
CHEMBL1813478
Bioactive
(3aS,6aR)-3a-(3,4-dichlorophenyl)-2-methyl-1,3,4,5,6,6a-hexahydrocyclopenta[c]pyrrole CFAMM00026918
CHEMBL356688
Bioactive
NCGC00024624-01 CFAMM00026881
CHEMBL1683874
Bioactive
AGN-PC-09QJJF CFAMM00026861
CHEMBL378536
Bioactive
AGN-PC-0764XC CFAMM00026874
CHEMBL106437
Bioactive
BD 737 CFAMM00026867
CHEMBL1683882
Bioactive
AGN-PC-09QGY6 CFAMM00026880
CHEMBL1683875
Bioactive
AGN-PC-09QGY4 CFAMM00026944
CHEMBL2326691
Bioactive
3-(3,4-dichlorophenyl)-1-methylazepane CFAMM00026909
CHEMBL2321995
Bioactive
3-(3,4-dichlorophenyl)-1-methyl-2,3,4,7-tetrahydroazepine CFAMM00026963
CHEMBL2181454
Bioactive
(4-chlorophenyl)methyl-[[(1S,5R)-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methyl]-dimethylazanium;iodide CFAMM00026992
CHEMBL295880
Bioactive
(Z,4R)-4-(4-chlorophenyl)-N-[(2-methylpropan-2-yl)oxy]-1-azabicyclo[3.2.1]octan-6-imine CFAMM00026916
CHEMBL1200765
Bioactive
SIBUTRAMINE HCl CFAMM00026908
CHEMBL59047
Bioactive
CHEMBL59047 CFAMM00026985
CHEMBL295882
Bioactive
(4S)-4-(4-chlorophenyl)-N-methoxy-1-azabicyclo[3.2.1]octan-6-imine CFAMM00026984
CHEMBL298420
Bioactive
(E,4R)-4-(4-chlorophenyl)-N-methoxy-1-azabicyclo[3.2.1]octan-6-imine CFAMM00026907
CHEMBL1642910
Bioactive
1-[(2S,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-N,N-dimethylmethanamine CFAMM00026934
CHEMBL113336
Bioactive
4-Piperidinecarbonitrile, 4-(3,4-dichlorophenyl)-1-methyl- CFAMM00026961
CHEMBL287032
Bioactive
AGN-PC-00FBR6 CFAMM00026990
CHEMBL2048227
Bioactive
4-(4-chlorophenyl)-1-propylpiperidine CFAMM00026906
CHEMBL1642911
Bioactive
1-[(2R,4S)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-2-yl]-N,N-dimethylmethanamine CFAMM00026969
CHEMBL219707
Bioactive
2-[1-(4-chlorophenyl)-2-cyclohexylethyl]piperidine CFAMM00026857
CHEMBL537429
Bioactive
(1R,9aR)-1-(2-chlorophenyl)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine;hydrochloride CFAMM00026947
CHEMBL102999
Bioactive
AC1O3LMV CFAMM00026960
CHEMBL47188
Bioactive
(Z,4S)-4-(4-chlorophenyl)-N-methoxy-1-azabicyclo[3.2.1]octan-6-imine CFAMM00026989
CHEMBL2205697
Bioactive
2-(4-chlorophenyl)ethyl-[[(1S,5R)-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methyl]-dimethylazanium;iodide CFAMM00026863
CHEMBL1683885
Bioactive
AGN-PC-09QJJG CFAMM00026876
CHEMBL1683871
Bioactive
(1-(3,4-Dichlorophenyl)Cyclohexyl)Methanamine CFAMM00026939
CHEMBL557576
Bioactive
AGN-PC-005DJM CFAMM00026953
CHEMBL104992
Bioactive
SureCN5935213 CFAMM00026919
CHEMBL441864
Bioactive
2-[1-(4-chlorophenyl)-4-phenylbutyl]piperidine CFAMM00026856
CHEMBL364469
Bioactive
AGN-PC-004OCS CFAMM00026946
CHEMBL373773
Bioactive
2-[1-(4-chlorophenyl)-2-phenylethyl]piperidine CFAMM00026925
CHEMBL322365
Bioactive
(3S,4S)-3-(4-chlorophenyl)-4-hexyl-8-methyl-8-azabicyclo[3.2.1]octane CFAMM00026904
CHEMBL1684048
Bioactive
AGN-PC-09QKGC CFAMM00026910
CHEMBL45111
Bioactive
(4R)-4-(4-chlorophenyl)-N-methoxy-1-azabicyclo[3.2.1]octan-6-imine CFAMM00026958
CHEMBL1813486
Bioactive
(3aR,7aR)-7a-[(3,4-dichlorophenyl)methyl]-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026974
CHEMBL598270
Bioactive
Clofilium tosylate CFAMM00026987
CHEMBL279352
Bioactive
SureCN433751 CFAMM00026937
CHEMBL219334
Bioactive
2-[1-(4-chlorophenyl)-2-ethylbutyl]piperidine CFAMM00026957
CHEMBL107717
Bioactive
N'-[2-(3,4-dichlorophenyl)ethyl]-N,N'-dimethyl-N-(4-pyrrolidin-1-ylbutyl)propane-1,3-diamine CFAMM00026854
CHEMBL1813306
Bioactive
(3aR,7aS)-7a-(2,4-dichlorophenyl)-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026923
CHEMBL75300
Bioactive
AGN-PC-074IK5 CFAMM00026873
CHEMBL285403
Bioactive
SureCN10376923 CFAMM00026887
CHEMBL374769
Bioactive
2-[1-(4-chlorophenyl)-3,3-dimethylbutyl]piperidine CFAMM00026950
CHEMBL75036
Bioactive
AGN-PC-074IIN CFAMM00026902
CHEMBL1684042
Bioactive
AGN-PC-04SSM3 CFAMM00026866
CHEMBL2048525
Bioactive
1-[(1S,3S,4R,5R)-3-(4-chlorophenyl)-8-(3-fluoranylpropyl)-8-azabicyclo[3.2.1]octan-4-yl]-N,N-dimethylmethanamine CFAMM00026972
CHEMBL32270
Bioactive
(6S,10bS)-9-chloro-6-(4-chlorophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline CFAMM00026922
CHEMBL219281
Bioactive
2-[1-(4-chlorophenyl)-3-phenylpropyl]piperidine CFAMM00026872
CHEMBL1743789
Bioactive
(6R,10bS)-6-(2-chlorophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline;hydrobromide CFAMM00026901
CHEMBL1684043
Bioactive
AGN-PC-04SSK3 CFAMM00026978
CHEMBL324620
Bioactive
NCI60_038432 CFAMM00026858
CHEMBL430466
Bioactive
(1S,2S)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-pyrrolidin-1-ylcyclohexan-1-amine CFAMM00026885
CHEMBL358368
Bioactive
1-[3-(3,4-dichlorophenyl)-2-bicyclo[2.2.2]octanyl]-N,N-dimethylmethanamine CFAMM00026927
CHEMBL2115570
Bioactive
(3S,4S)-4-(2-chloroethenyl)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane CFAMM00026864
CHEMBL1683886
Bioactive
AGN-PC-09QGY7 CFAMM00026877
CHEMBL1683870
Bioactive
SureCN3518106 CFAMM00026954
CHEMBL559186
Bioactive
(1S,9aR)-1-(3,4-dichlorophenyl)-2,3,4,6,7,8,9,9a-octahydro-1H-quinolizine;hydrochloride CFAMM00026870
CHEMBL1683888
Bioactive
AGN-PC-09QKFC CFAMM00026883
CHEMBL218848
Bioactive
2-[1-(4-chlorophenyl)-2-methylpropyl]piperidine CFAMM00026968
CHEMBL2206523
Bioactive
4-(4-chlorophenyl)-2-methyl-3,4-dihydro-1H-isoquinoline CFAMM00026905
CHEMBL2321997
Bioactive
(3S)-3-(3,4-dichlorophenyl)-1-methyl-2,3,4,7-tetrahydroazepine CFAMM00026898
CHEMBL1684045
Bioactive
AGN-PC-093IQV CFAMM00026988
CHEMBL375118
Bioactive
2-[(4-chlorophenyl)-cyclopentylmethyl]piperidine CFAMM00026862
CHEMBL1683884
Bioactive
SureCN3517701 CFAMM00026967
CHEMBL319805
Bioactive
SureCN7084956 CFAMM00026875
CHEMBL1683878
Bioactive
AGN-PC-09QLBC CFAMM00026981
CHEMBL1813315
Bioactive
(3aR,7aS)-7a-(3,4-dichlorophenyl)-2-methyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026994
CHEMBL1743796
Bioactive
(6S,10bS)-6-(3-chlorophenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline;hydrobromide CFAMM00026855
CHEMBL2048524
Bioactive
1-[(1S,3S,4R,5R)-3-(4-chlorophenyl)-8-(2-fluoranylethyl)-8-azabicyclo[3.2.1]octan-4-yl]-N,N-dimethylmethanamine CFAMM00026868
CHEMBL1683883
Bioactive
SureCN3519163 CFAMM00026931
CHEMBL335204
Bioactive
3-(4-chlorophenyl)-7-ethyl-7-azabicyclo[2.2.1]heptane CFAMM00026889
CHEMBL141893
Bioactive
AGN-PC-003SR3 CFAMM00026980
CHEMBL1813316
Bioactive
(3aS,7aR)-7a-(3,4-dichlorophenyl)-2-ethyl-3,3a,4,5,6,7-hexahydro-1H-isoindole CFAMM00026993
CHEMBL1643898
Bioactive
2-butyl-3-(4-chlorophenyl)-1-azabicyclo[2.2.2]oct-2-ene CFAMM00026903
CHEMBL316797
Bioactive
SureCN5935258 CFAMM00026896
CHEMBL323476
Bioactive
NCI60_038430 CFAMM00026973
CHEMBL9484
Bioactive
Clofilium CFAMM00026894
20302210
Patent Compound
AGN-PC-02RNOZ CFAMM00026935
54512673
Patent Compound
AGN-PC-0A7ADS CFAMM00026962
19823784
Patent Compound
AGN-PC-02KLNO CFAMM00026991
57194860
Patent Compound
AGN-PC-0BP96E CFAMM00026955
19823721
Patent Compound
AGN-PC-02KLM9 CFAMM00026971
23342852
Patent Compound
SureCN11486228 CFAMM00026932
13083344
Patent Compound
AGN-PC-00KT3H CFAMM00026952
115925
Patent Compound
3-(4-chlorophenyl)-N,N-dimethylpropan-1-amine CFAMM00026945
12951701
Patent Compound
AGN-PC-00K85V CFAMM00026897
3732780
Patent Compound
4-[(4-chlorophenyl)methyl]piperidine CFAMM00026924
13189987
Patent Compound
AGN-PC-00LD57 CFAMM00026966
22458793
Patent Compound
AGN-PC-03P7JH CFAMM00026951
13083296
Patent Compound
AGN-PC-00KT2B CFAMM00026917
54287336
Patent Compound
SureCN7414359 CFAMM00026930
22649570
Patent Compound
AGN-PC-00KBAV CFAMM00026986
9922196
Patent Compound
AGN-PC-0CQ6J3
Statistics of CFAM Database
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
How to cite our database
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering.
Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
Last update by
2014.08.29
48682 visits since 2014 .........
Dr.
Chen Yuzong
Deputy
Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore
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