CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Potassium-transporting ATPase alpha chain 1 Inhibitor Rabeprazole Family
No. of Seeds 4 No. of Other Members 113
Family Centroid CFAMM00027797 Functional Category Approved Drug with Human Metabolite
Superfamily Potassium-transporting ATPase alpha chain 1 Inhibitor Rabeprazole Superfamily
Class Class 145

Cousin Family NamesSeedsMembers
Potassium-transporting ATPase alpha chain 1 Inhibitor Pantopra... 1 3
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Sodium/hydrogen exchanger 1 inhibitor 2-[(E)-[5-chloro-2-[(6-m... 1 7
Potassium-transporting ATPase alpha chain 1 inhibitor 2-[[3-(d... 4 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Neuropeptide Y receptor type 5 ligand 6-ethylsulfonyl-2-(4-phe... 4 4
Methionine aminopeptidase 2 inhibitor SureCN5376830 family 2 1
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 4
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3
Cytochrome P450 2C19 and Cytochrome P450 1A2 inhibitor 2-hepty... 4 4
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 1 0
Prostaglandin G/H synthase 1 inhibitor 2-ethylsulfanyl-1-(4-me... 1 1


External ID

Functional Category

Molecule Name

CFAMM00027714 DAP000180 Approved Drug Omeprazole
CFAMM00027817 DAP001443 Approved Drug Dexlansoprazole
CFAMM00027799 DAP000725 Approved Drug Lansoprazole
CFAMM00027797 DAP000727 Approved Drug Rabeprazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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