CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD163
Family Name Serotonin re-uptake Inhibitor Fluoxetine Family
No. of Seeds 18 No. of Other Members 682
Family Centroid CFAMM00029001 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily monoamine reuptake and receptor binding Fluoxetine Reboxetine Bevantolol Nebivolol Superfamily
Class Class 149

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1I liga... 5 209
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 61 433
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Histamine H1 receptor Ligand Doxepin Family 8 89
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Alpha-1 adrenergic receptor ligand Dextroamphetamine derivativ... 5 29
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Sigma non-opioid intracellular receptor 1 ligand opiate Dextro... 9 33
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Alpha adrenergic receptor Ligand Phenoxybenzamine Family 4 63
Beta adrenergic receptor Ligand Metipranolol Family 5 1
Beta-1 adrenergic receptor Ligand Oxprenolol Family 3 27
Histamine H1 receptor Ligand Diphenhydramine Family 5 75
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Dulo... 8 6
Sodium channel protein type 5 subunit alpha Ligand Mexiletine ... 7 74
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Glycoprotein IIb/IIIa receptor Ligand Tirofiban Family 4 173
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Synaptic vesicular amine transporter Inhibitor Tetrabenazine F... 13 425
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Tyrosinase Inhibitor Monobenzone Family 6 197
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Oestrogen receptor ligand Dienestrol Family 35 440
Beta-1 adrenergic receptor Ligand Nebivolol Family 5 22
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Muscarinic acetylcholine receptor Ligand Methantheline Family 6 8
Muscarinic acetylcholine receptor M3 Ligand Darifenacin Family 3 17
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Nicotinic acetylcholine receptor Ligand Benztropine Mesylate F... 10 20
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Zucapsacin family 7 177
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Gadoxetate family 1 3
Serine/threonine-protein kinase PLK1 Inhibitor On 019190.na Fa... 16 138
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Melatonin receptor type 1A Ligand Agomelatine Family 12 164
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor Lig... 4 35
Substance-P receptor Ligand DA-5018 Family 14 73
Translocator protein Inhibitor Dextofisopam Family 3 250
Substance-P receptor Ligand Ezlopitant Family 10 207
5-hydroxytryptamine receptor 1A Ligand MN-305 Family 12 26
5-hydroxytryptamine receptor 2A Ligand Pimavanserin Family 4 23
D(3) dopamine receptor Ligand U-99194A Family 7 33
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Irdabisant family 49 53
Acolbifene family 10 115
Dapoxetine family 3 40
TS-071 family 8 36
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Potassium voltage-gated channel subfamily H member 2 Ligand Al... 2 3
A disintegrin and metalloproteinase with thrombospondin motifs... 7 119
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
Arachidonate 5-lipoxygenase Inhibitor Bw A4C Family 3 18
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
C-C chemokine receptor type 5 Ligand E-913 Family 6 44
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Extracellular calcium-sensing receptor Ligand Nps 568 Family 5 54
Neuropeptide Y receptor type 5 Ligand NPY-5 Receptor Antagonis... 1 1
Tumor necrosis factor Inhibitor Y-39041 Family 9 51
Voltage-gated sodium channel Ligand SB-221420-A Family 1 3
Voltage-dependent L-type calcium channel Ligand PD173212 Family 24 104
Histamine H3 receptor Ligand A-331440 Family 6 7
Histamine H3 receptor Ligand UCL-2138 Family 23 172
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Cathepsin S Inhibitor 2-[(2',3',4'-trifluorobiphenyl-2-yl)oxy]... 2 16
5-hydroxytryptamine receptor 2A Ligand Phenethylamine Family 3 25
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 24
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Plasmepsin-1 and Plasmepsin-2 Inhibitor PS-777621 Family 11 13
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Disintegrin and metalloproteinase domain-containing protein 17... 25 36
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 8 66
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Extracellular calcium-sensing receptor and Potassium voltage-g... 3 11
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Mitogen-activated protein kinase 14 Inhibitor N-(4-(trifluorom... 8 39
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Angiopoietin-1 receptor and Cyclin-dependent kinase 1 Inhibito... 2 10
Dipeptidyl peptidase 4 Inhibitor (2-chloro-6-phenoxyphenyl)met... 17 24
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 9 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 11 21
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Leukotriene A-4 hydrolase Inhibitor 1-butoxy-4-phenoxybenzene ... 3 85
Acetylcholinesterase and Cholinesterase Inhibitor Caproctamine... 7 17
Oxytocin receptor Ligand [mpa1, D-tyr(et)2, D-tic7]ot Family 43 26
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Histamine H3 receptor Ligand (r)-1-(2-methoxyphenethyl)-2-meth... 10 27
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 33
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
5-hydroxytryptamine receptor 2A Ligand 3-methoxy-9-aminomethyl... 7 14
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
Androgen receptor Ligand 3-methoxy-4-(m-tolyloxy)benzonitrile ... 3 29
Androgen receptor Ligand 4-(m-tolyloxy)-2-(trifluoromethyl)ben... 7 65
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Fatty-acid amide hydrolase 1 Inhibitor N-butylcarbamic Acid Bi... 9 31
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 2
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 5 14
Histamine H3 receptor Ligand 1-(3-(2-(3-methoxyphenoxy)ethoxy)... 3 9
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 6
Sodium-dependent serotonin transporter Inhibitor 4-(2-((dimeth... 3 1
Sodium-dependent noradrenaline transporter Inhibitor WAY-25680... 4 6
5-hydroxytryptamine receptor 2A and D(1A) dopamine receptor Li... 8 33
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Leukotriene A-4 hydrolase Inhibitor (r/s)-2-((4-phenoxyphenoxy... 7 18
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Fatty-acid amide hydrolase 1 Inhibitor 3-(trifluoromethyl)phen... 3 0
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 10 15
Cytochrome P450 2D6 Inhibitor 4-methylaminomethyl-7-methoxycou... 3 80
Indoleamine 2,3-dioxygenase 1 Inhibitor 4-methoxybenzenemethan... 2 26
Renin Inhibitor Ro-65-7219 Family 10 8
Arachidonate 5-lipoxygenase Inhibitor 2-(4-butoxy-phenyl)-n-hy... 3 9
5-hydroxytryptamine receptor 1A Ligand 9-methoxy-1,2,3,4-tetra... 7 10
5-hydroxytryptamine receptor 2A Ligand C-(9h-xanthen-9-yl)-met... 3 5
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 3
5-hydroxytryptamine receptor 2A Ligand (s)-(-)-(4,5,6-trimetho... 3 1
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Amine oxidase [flavin-containing] B Inhibitor (r)-n2-{4-[(3-ch... 3 0
Tyrosinase Inhibitor 1-(3-phenoxypropyl)-4-(piperidin-1-yl)pip... 2 13
5-hydroxytryptamine receptor 2A Ligand 1-(2,6-dimethoxy-4-meth... 14 3
Fatty-acid amide hydrolase 1 Inhibitor 8-phenyloctylcarbamic A... 12 1
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 24 73
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 7 0
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 2 1
5-hydroxytryptamine receptor 1A and Alpha-1D adrenergic recept... 2 2
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 7 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 6 19
Histamine H3 receptor ligand SureCN4319687 family 8 15
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 0
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Leukotriene A-4 hydrolase inhibitor SureCN13809114 family 2 7
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 6 5
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 8 4
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 2
Mu-type opioid receptor and Sigma non-opioid intracellular rec... 10 20
Leukotriene A-4 hydrolase inhibitor 3-[3-(4-benzylphenoxy)prop... 2 0
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 4 10
Sigma non-opioid intracellular receptor 1 ligand 1-[4-(4-metho... 1 0
D(4) dopamine receptor and D(3) dopamine receptor ligand N-[2-... 6 15
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Melatonin receptor type 1A ligand [7-methoxy-1-[2-(propanoylam... 3 0
Survival motor neuron protein and Lysine-specific demethylase ... 1 16
D(1A) dopamine receptor and D(3) dopamine receptor ligand N,N-... 3 1
Squalene synthase inhibitor 3-[4-[[(E)-ethylideneamino]oxymeth... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 7 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 1
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
D(3) dopamine receptor ligand S 14297 family 1 2
Prelamin-A/C and Solute carrier organic anion transporter fami... 1 15
Substance-P receptor ligand AGN-PC-02K8FR family 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 6 0
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
DNA-(apurinic or apyrimidinic site) lyase and Menin inhibitor ... 1 6
5-hydroxytryptamine receptor 1A ligand [(1S,2R)-8-methoxy-2-(p... 4 0
D(2) dopamine receptor and D(1A) dopamine receptor ligand ISOM... 2 5
5-hydroxytryptamine receptor 1A and Sodium-dependent noradrena... 2 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 11 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 6 21
Nitric oxide synthase, inducible and Cytochrome P450 2D6 inhib... 2 1
Histone deacetylase and Histone deacetylase 3 inhibitor (3S,6S... 1 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 12 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 4
Histamine H3 receptor ligand cyclohexyl-[4-(3-piperidin-1-ylpr... 4 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Histamine H3 receptor ligand SureCN5093910 family 3 16
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 28
Histamine H3 receptor ligand 1-[[4-[4-[(1R)-4-(4-methoxyphenox... 2 1
Transporter and 5-hydroxytryptamine receptor 2C ligand CHEMBL1... 5 5
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-(4-... 2 6
5-hydroxytryptamine receptor 1A ligand oxalic acid;(1R,5S)-5-[... 2 0
Pol polyprotein inhibitor MDL 74538 family 11 1
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 1 0
Muscarinic acetylcholine receptor M3 ligand AGN-PC-005QPZ family 1 0
Carbonic anhydrase 7 and Carbonic anhydrase 14 inhibitor 4-(6-... 7 8
Histamine H3 receptor ligand SureCN6071181 family 2 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 1 0
Amine oxidase [flavin-containing] B inhibitor Phthalonitrile a... 1 6
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 5 1
Kinesin-like protein KIF11 inhibitor 2-amino-5-(4-methoxypheny... 1 4
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
5-hydroxytryptamine receptor 7 and Alpha-2C adrenergic recepto... 3 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 14 1
Muscarinic acetylcholine receptor M2 and Muscarinic acetylchol... 7 1
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Sodium-dependent serotonin transporter and Histamine H3 recept... 7 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 4 0
Histamine H3 receptor and Sodium-dependent serotonin transport... 3 6
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 1 7
Putative Bioactive 5-hexyl-2-[4-[(4-methylpiperazin-1-yl)methy... 2 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 3 0
Sigma non-opioid intracellular receptor 1 ligand 4-[[1-[(2-bro... 2 0
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 14
Cathepsin S and Cathepsin L1 inhibitor benzyl N-[(2S)-1-oxo-1-... 2 2
Neuronal acetylcholine receptor subunit alpha-10 ligand (2S)-2... 1 0
Pol polyprotein inhibitor (3S)-N-tert-butyl-2-[(2R)-2-[(3S,6S,... 3 1
Substance-P receptor ligand (5S,10S)-5-(4-fluorophenyl)-10-(2-... 3 2
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Squalene synthase inhibitor [4-[3-(propan-2-ylamino)propoxy]ph... 1 3
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 6
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 11
Histamine H3 receptor and Sodium-dependent serotonin transport... 1 0
Scytalone dehydratase inhibitor 2-cyano-N-[(1S,2R)-1-(2-cyanop... 5 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 2 0
Sodium-dependent noradrenaline transporter and Cytochrome P450... 11 2
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 0
Histamine H3 receptor and D(3) dopamine receptor ligand AGN-PC... 1 0
Sigma non-opioid intracellular receptor 1 ligand SureCN7450653... 1 0
Bifunctional epoxide hydrolase 2 and Cytochrome P450 2C9 inhib... 2 1
Sodium-dependent serotonin transporter inhibitor 1-[5-methoxy-... 1 0
Histamine H3 receptor and Histamine H1 receptor ligand AGN-PC-... 1 0
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 2
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 0
Squalene monooxygenase inhibitor 2-[[3-[[[(E)-6,6-dimethylhept... 4 4
Membrane primary amine oxidase inhibitor 2-hydrazinyl-1-(4-met... 1 2
Muscleblind-like protein 1 and Ferritin light chain inhibitor ... 1 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 4 2
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 1
Steroidogenic factor 1 and Nuclear receptor subfamily 5 group ... 1 1
Trace amine-associated receptor 1 ligand SureCN13886619 family 1 1
Trace amine-associated receptor 1 ligand 4-[4-(2-AMINO-ETHYL)-... 1 0
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 0
Mu-type opioid receptor ligand 2-[[2-[(2R)-2-ethyl-4-(4-fluoro... 1 3
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-07... 2 6
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 0
Histamine H3 receptor and Histamine H1 receptor ligand (NE)-N-... 1 1
C-C chemokine receptor type 2 ligand (E)-N-[(1S,3R)-3-[[4-(4-m... 1 6
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2
Metabotropic glutamate receptor 2 ligand (5R)-3-[[4-(4-ethoxyp... 3 9
Sodium-dependent serotonin transporter and Sodium-dependent no... 1 0
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 2 3
Histamine H3 receptor ligand (NE)-N-[2-[2-(dimethylamino)ethox... 3 2
Sphingosine 1-phosphate receptor 1 ligand (3S)-3-amino-5-(4-he... 1 1
Beta-lactamase inhibitor AGN-PC-0A9UJZ family 1 3
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-0A9S9E... 1 0
Cannabinoid receptor 1 and Monoglyceride lipase ligand 4-(4-ph... 4 4
Sodium-dependent serotonin transporter and Transporter inhibit... 1 0
Arachidonate 5-lipoxygenase inhibitor AGN-PC-074BF6 family 1 1
Benzyloxycarbonyls Metabolite 4-Methoxybenzyl formate Family 1 7
Phenols and Derivatives Metabolite (±)-Flufenprox Family 1 13
Putative NP ZINC04061066 Family 18 0
Putative NP ZINC04029215 Family 6 0
methanimine NP ZINC04027837 Family 18 0
ahydropyrano[3,2-c]chromene NP ZINC04023039 Family 16 2
Putative NP ZINC02132531 Family 4 0
3-azaniumyl-3-(4-methoxynaphthalen-1-yl)propanoate NP ZINC0027... 2 1
Putative NP ZINC01322649 Family 2 0
Putative NP ZINC38201335 Family 8 0
Putative NP ZINC00050501 Family 6 4
3-azaniumyl-3-(4-butoxyphenyl)butanoate NP 3-amino-3-(4-butoxy... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00028812 DAP000721 Approved Drug Atomoxetine
CFAMM00029001 DAP000186 Approved Drug Fluoxetine
CFAMM00029356 CHEMBL1257031 Bioactive S-(+)-Fluoxetine hydrochloride
CFAMM00029225 CHEMBL20768 Bioactive SureCN8092974
CFAMM00029089 CHEMBL129931 Bioactive N-(3-phenoxypropyl)-3-phenylpropan-1-amine
CFAMM00028862 CHEMBL1201082 Bioactive FLUOXETINE HYDROCHLORIDE
CFAMM00029081 CHEMBL334989 Bioactive 3-(4-methylphenyl)-N-(3-phenoxypropyl)propan-1-amine
CFAMM00028938 DNC008234 Investigative Drug 1-(4-(benzyloxy)phenethyl)pyrrolidine
CFAMM00028871 DNC008743 Investigative Drug (S)-Norfluoxetine
CFAMM00028907 DNC014532 Investigative Drug FLUOXETINE HYDROCHLORIDE
CFAMM00028870 DNC008744 Investigative Drug (R)-Norfluoxetine
CFAMM00028981 DNC010049 Investigative Drug 4-(2-((3-fluorophenoxy)methyl)phenyl)piperidine
CFAMM00029054 DNC010052 Investigative Drug 4-(2-(4-fluorobenzyloxy)phenyl)piperidine
CFAMM00029312 DNC012535 Investigative Drug [3-(Biphenyl-4-yloxy)-propyl]-dimethyl-amine
CFAMM00028986 DNC010047 Investigative Drug 4-(2-(2-fluorobenzyloxy)phenyl)piperidine
CFAMM00029439 DNC014051 Investigative Drug 1-(4-(benzyloxy)phenyl)propan-2-amine
CFAMM00029398 DNC010039 Investigative Drug 4-(2-(benzyloxy)-6-fluorophenyl)piperidine
CFAMM00029177 DNC010109 Investigative Drug (R)-2-(4-Benzylphenoxymethyl)pyrrolidine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21760 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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