CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Amiloride-sensitive sodium channel subunit alpha Ligand Amiloride Family
No. of Seeds 3 No. of Other Members 10
Family Centroid CFAMM00029573 Functional Category Approved Drug with Natural Product
Superfamily Amiloride-sensitive sodium channel subunit alpha Ligand Amiloride Superfamily
Class Class 150

Cousin Family NamesSeedsMembers
Amiloride-sensitive sodium channel subunit alpha ligand AGN-PC... 1 1


External ID

Functional Category

Molecule Name

CFAMM00029573 DAP000187 Approved Drug Amiloride
CFAMM00029588 CHEMBL1256020 Bioactive 5-(N,N-Dimethyl)amiloride hydrochloride
CFAMM00029577 CHEMBL1398126 Bioactive Amiloride hydrochloride dihydrate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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