CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Antithrombin-III Inhibitor Heparin Family
No. of Seeds 2 No. of Other Members 74
Family Centroid CFAMM00029611 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Antithrombin-III Inhibitor Heparin Superfamily
Class Class 152

Cousin Family NamesSeedsMembers
Kawain family 1 29
72 kDa type IV collagenase and Macrophage metalloelastase Inhi... 2 5
Prostaglandin E2 receptor EP3 subtype and Prostaglandin E2 rec... 2 4
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor Lorneic... 1 1
Histone deacetylase 2 and Histone deacetylase 8 inhibitor 2-hy... 1 1
Shiga toxin 1 variant B subunit and Shiga toxin 1 variant A su... 1 13
Retinoic acid receptor RXR-alpha and Retinoic acid receptor RX... 9 10
Peptidyl-glycine alpha-amidating monooxygenase inhibitor AGN-P... 1 0
Monoglyceride lipase inhibitor oxan-2-ylmethyl (E)-3-(4-phenyl... 1 2
Toll-like receptor 4 ligand dimethyl 2-[(2-fluorophenyl)methyl... 4 11
Benzyloxycarbonyls Metabolite Benzyl acetate Family 5 53
Aromatic Homomonocyclic Compounds Metabolite Dimethylbenzyl ca... 2 11
Cinnamic Acid Derivatives Metabolite Cinnamyl cinnamate Family 1 7
Cinnamic Acid Derivatives Metabolite Tetrahydrofurfuryl cinnam... 1 4
Phenylpropenes Metabolite alpha-Amylcinnamyl acetate Family 3 3
Phenylpropenes Metabolite alpha-Amylcinnamyl formate Family 1 1
Cinnamic Acid Derivatives Metabolite alpha-Terpinyl cinnamate ... 1 4


External ID

Functional Category

Molecule Name

CFAMM00029611 DAP000189 Approved Drug Heparin
CFAMM00029676 DNC007083 Investigative Drug 3-(2-cinnamylphenyl)acrylic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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