CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD168
Family Name Alpha adrenergic receptor Ligand Pseudoephedrine Family
No. of Seeds 4 No. of Other Members 96
Family Centroid CFAMM00029719 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Alpha adrenergic receptor Ligand Pseudoephedrine Superfamily
Class Class 154

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Tyrosine 3-monooxygenase Inhibitor L-tyrosine Family 4 36
Alpha-1B adrenergic receptor ligand Morpholine derivative Phen... 4 152
Muscarinic acetylcholine receptor M1 Ligand Trihexyphenidyl Fa... 14 199
Histamine H1 receptor ligand diphenylpiperidine analog Dipheny... 13 224
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Mu-type opioid receptor ligand opiate Methadyl Acetate Family 5 9
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Sulfen... 5 13
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 5 11
Substance-P receptor Ligand L-733060 Family 19 71
Adenosine receptor A3 and Mu-type opioid receptor Ligand GBR-1... 80 110
4-aminobutyrate aminotransferase, mitochondrial Inhibitor 4-hy... 2 6
Substance-P receptor Ligand SCH-388714 Family 26 8
Cytochrome P450 2D6 Inhibitor Bs 7840 Family 4 9
Sodium-dependent noradrenaline transporter Inhibitor (r)-1-((s... 3 8
Potassium voltage-gated channel subfamily A member 5 Ligand 2-... 3 1
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 11 3
Potassium voltage-gated channel subfamily H member 2 Ligand [1... 2 23
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 9 7
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 2 7
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 1 8
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-ri... 5 12
Sodium-dependent dopamine transporter and Sodium-dependent nor... 5 2
Sodium-dependent dopamine transporter and Sodium-dependent nor... 4 19
Vesicular acetylcholine transporter inhibitor BENZOVESAMICOL f... 7 4
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 13 0
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Vesicular acetylcholine transporter inhibitor (1R,2R)-2-spiro[... 3 2
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 4
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Sodium-dependent dopamine transporter and Sodium-dependent ser... 2 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 7
Phenylalanine--tRNA ligase alpha subunit inhibitor TCMDC-14030... 1 1
Membrane primary amine oxidase and Amine oxidase [flavin-conta... 2 0
Nuclear receptor ROR-gamma ligand Bio2_000636 family 3 3
Mannosyl-oligosaccharide 1,2-alpha-mannosidase and Endoplasmic... 2 2
Dibenzocycloheptenes Metabolite E-10-Hydroxynortriptyline Family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00029721 DAP000228 Approved Drug Ephedrine
CFAMM00029719 DAP000195 Approved Drug Pseudoephedrine
CFAMM00029741 DAP000899 Approved Drug Phenylpropanolamine
CFAMM00029778 CHEMBL1523964 Bioactive EPHEDRINE SULFATE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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