CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Plasminogen Inhibitor Tranexamic Acid Family
No. of Seeds 4 No. of Other Members 14
Family Centroid CFAMM00029895 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Plasminogen and Voltage-dependent T-type calcium channel subunit alpha-1I Binder Superfamily
Class Class 157

Cousin Family NamesSeedsMembers
Plasminogen Inhibitor Aminocaproic Acid Family 4 37
Gamma-aminobutyric acid B receptor Ligand Gabapentin Family 4 26
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 3 5
Glutamate receptor ionotropic, NMDA 1 Ligand Cycloleucine Family 2 4
Leukotriene A-4 hydrolase Inhibitor 8(s)-amino-2(r)-methyl-7-o... 2 9
Glutamate receptor ionotropic, kainate 1 Ligand (2s,4r)-4-(3-m... 2 7
Carboxypeptidase B2 and Carboxypeptidase B inhibitor 7-amino-2... 1 0
Group VII phospholipase A2 and Group 10 secretory phospholipas... 2 2
Amino Acids and Derivatives Metabolite L-Isoleucine Family 4 5


External ID

Functional Category

Molecule Name

CFAMM00029895 DAP000199 Approved Drug Tranexamic Acid
CFAMM00029896 DNC012971 Investigative Drug (S)-2-amino-2-cyclohexylacetic acid
CFAMM00029886 DNC012966 Investigative Drug rac-2-amino-5-cyclohexylpentanoic acid
CFAMM00029885 DNC012969 Investigative Drug (S)-2-amino-3-cyclohexylpropanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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