CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Plasminogen Inhibitor Aminocaproic Acid Family
No. of Seeds 4 No. of Other Members 37
Family Centroid CFAMM00029938 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Plasminogen Inhibitor Aminocaproic Acid Superfamily
Class Class 158

Cousin Family NamesSeedsMembers
NMDA receptor Ligand L-glutamic Acid Family 6 32
Plasminogen Inhibitor Tranexamic Acid Family 4 14
Delta-aminolevulinic acid dehydratase Inhibitor Aminolevulinic... 3 2
4-aminobutyrate aminotransferase, mitochondrial Inhibitor L-al... 3 23
Voltage-dependent T-type calcium channel subunit alpha-1I Liga... 3 5
Calmodulin Inhibitor N-trimethyllysine Family 1 14
Alanine racemase and Cyclin-dependent kinase 2 Inhibitor Lysin... 1 3
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]... 2 3
Leukotriene A-4 hydrolase Inhibitor 8(s)-amino-2(r)-methyl-7-o... 2 9
Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ... 2 10
Amino Acids and Derivatives Metabolite L-Isoleucine Family 4 5
Amino Acids and Derivatives Metabolite (3S,5S)-3,5-Diaminohexa... 1 0
Keto-Acids and Derivatives Metabolite (S)-5-Amino-3-oxohexanoa... 1 0
Amino Acids and Derivatives Metabolite L-Hypoglycin A Family 1 1
2,6-bis(azaniumyl)heptanedioate NP ZINC02124046 Family 5 4
Putative NP ZINC02108714 Family 22 9
pentanoate NP (2s)-2,5-diammoniopentanoate Family 2 2
(2S)-2-azaniumylhexanedioate NP L-2-aminoadipate Family 1 0


External ID

Functional Category

Molecule Name

CFAMM00029938 DAP000200 Approved Drug Aminocaproic Acid
CFAMM00029909 DNC002729 Investigative Drug Norleucine
CFAMM00029907 DNC002625 Investigative Drug Delta-Amino Valeric Acid
CFAMM00029906 DNC002567 Investigative Drug 4-Amino Hexanoic Acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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