CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD177
Family Name Cannabinoid receptor 1 Ligand Marinol Family
No. of Seeds 32 No. of Other Members 454
Family Centroid CFAMM00030461 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Cannabinoid receptor 1 Ligand Marinol Superfamily
Class Class 161

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Fatty-acid amide hydrolase 1 Inhibitor Propofol Family 5 428
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor Mycophenola... 4 353
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor ligand Dienestrol Family 35 440
D-alanyl-D-alanine carboxypeptidase Inhibitor B-lactams Family 59 1364
Ipriflavone family 62 2480
Rotenone family 16 107
Agrimophol family 10 22
Salicin family 5 629
Leukotriene B4 receptor 1 Ligand LY293111 Family 24 79
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Steryl-sulfatase Inhibitor Stx 64 Family 7 160
Cannabinoid receptor 1 Ligand Cbd Cannabis Derivative Family 1 3
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
Oxi4503 family 4 27
TS-071 family 8 36
Interleukin-1 beta Inhibitor Diacerein Family 3 77
Arachidonate 15-lipoxygenase Inhibitor Isoscopoletin Family 5 98
Platelet-activating factor receptor Ligand L-652731 Family 5 116
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Arachidonate 15-lipoxygenase Inhibitor Hydrohalisulfate 1 Family 6 6
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 127
Oestrogen receptor and Estrogen receptor beta Ligand 3,8-dihyd... 20 57
Tubulin beta chain Inhibitor Combretastatin Family 3 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Arachidonate 15-lipoxygenase and Arachidonate 5-lipoxygenase I... 3 18
Sodium/glucose cotransporter 2 Inhibitor Maackiain Family 1 5
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Androgen receptor Ligand 2-methoxy-4-(o-tolyloxy)benzonitrile ... 5 12
MO15-related protein kinase Pfmrk Inhibitor WR-289012 Family 2 17
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Arachidonate 12-lipoxygenase, 12S-type and Arachidonate 15-lip... 2 1
Androgen receptor Ligand 2'-hydroxy-3-methoxy-biphenyl-4-carbo... 2 13
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
NAD(P)H dehydrogenase [quinone] 1 Inhibitor Ethyl Bis(4-hydrox... 5 7
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Amine oxidase [flavin-containing] B Inhibitor 7-fluoro-2-p-tol... 4 11
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Cytochrome P450 3A4 Inhibitor Diethoxyflourescein Family 3 9
Epidermal growth factor receptor Ligand 3-(3-chloro-phenyl)-5,... 10 64
Protein farnesyltransferase subunit beta Inhibitor Cylindrol A... 3 43
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Tyrosinase Inhibitor Kazinol S Family 1 0
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Tyrosinase Inhibitor 4-adamantyl Resorcinol Family 1 1
Androgen receptor Ligand Palodesangren E Family 12 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 27
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand [(6aR... 1 0
Estrogen receptor beta and Estrogen receptor ligand 3-fluoro-4... 6 42
Cannabinoid receptor 1 ligand 6,6,9-trimethyl-3-(6-nitrohex-2-... 1 0
Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethy... 2 4
Estrogen receptor beta and Estrogen receptor ligand SureCN4017... 3 5
Vitamin D3 receptor ligand (1R,3S,5Z)-5-[(2E)-2-[(3aS,7aR)-1-[... 1 2
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand SureC... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand (6aR,... 1 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 4 0
Potassium voltage-gated channel subfamily A member 3 ligand CH... 10 11
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 5-(2-... 3 0
Neuropeptide Y receptor type 5 and Thioredoxin glutathione red... 13 6
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[2-... 1 0
Multidrug resistance protein 1 inhibitor CHEMBL1 family 2 0
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 2 19
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 1-[3,... 4 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 17
Benzoxepines Metabolite Enokipodin A Family 1 0
Phenols and Derivatives Metabolite 2-(Ethoxymethyl)phenol Family 1 14


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00030461 DAP000207 Approved Drug Marinol
CFAMM00030294 CHEMBL325389 Bioactive SureCN14447598
CFAMM00030529 CHEMBL124194 Bioactive (6aR,10aR)-6,6,9-trimethyl-3-nonyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030053 CHEMBL398905 Bioactive (6aR,10aR)-6,6,9-trimethyl-3-(2-methylhexan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030386 CHEMBL67464 Bioactive (6aR,10aR)-3-heptyl-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030076 CHEMBL390404 Bioactive (6aR,10aR)-3-(1-heptylcyclobutyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030478 CHEMBL239840 Bioactive (6aR,10aR)-6,6,9-trimethyl-3-oct-1-en-2-yl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030654 CHEMBL71401 Bioactive (6aR,10aR)-6,6,9-trimethyl-3-[(2S,3R)-3-methyloctan-2-yl]-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030308 CHEMBL231268 Bioactive (6aR,10aR)-3-(1-hexylcyclobutyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030624 CHEMBL231369 Bioactive (6aR,10aR)-3-(1-heptylcyclopentyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030585 CHEMBL252949 Bioactive SureCN14447595
CFAMM00030623 CHEMBL231368 Bioactive (6aR,10aR)-3-(1-heptylcyclopropyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030476 CHEMBL108868 Bioactive (6aR,10aR)-3-(1-hexylcyclopentyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030584 CHEMBL252947 Bioactive SureCN14447592
CFAMM00030238 CHEMBL119914 Bioactive (6S,6aR,9R,10aR)-6-(2-hydroxyethyl)-9-(hydroxymethyl)-6-methyl-3-(2-methyloctan-2-yl)-6a,7,8,9,10,10a-hexahydrobenzo[c]chromen-1-ol
CFAMM00029985 CHEMBL411626 Bioactive SureCN12544469
CFAMM00029995 CHEMBL600602 Bioactive SureCN12590215
CFAMM00030552 CHEMBL159611 Bioactive AGN-PC-04CF01
CFAMM00030020 CHEMBL19847 Bioactive (6aR,10aR)-3-(1-hexylcyclopropyl)-6,6,9-trimethyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030519 CHEMBL111148 Bioactive (6aR)-6,6,9-trimethyl-3-(2-methyloctan-2-yl)-6a,7,8,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030096 CHEMBL252742 Bioactive (6aR,10aR)-6,6,9-trimethyl-3-(2-methylheptan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
CFAMM00030658 CHEMBL57802 Bioactive (6aR,10aR)-6,6-dimethyl-9-methylidene-3-(2-methyloctan-2-yl)-7,8,10,10a-tetrahydro-6aH-benzo[c]chromen-1-ol
CFAMM00030249 DCL000436 Clinical Trial Drug Anti-oxLDL
CFAMM00030202 DCL000770 Clinical Trial Drug Dexanabinol
CFAMM00030049 DNCL001599 Clinical Trial Drug Nabiximols
CFAMM00030160 DNC012984 Investigative Drug AM-411
CFAMM00030227 DNC008782 Investigative Drug DELTA 8-TETRAHYDROCANNOBINOL
CFAMM00030071 DNC000746 Investigative Drug HU210
CFAMM00030613 DNC008716 Investigative Drug JWH-229
CFAMM00030420 DNC005430 Investigative Drug HU-210
CFAMM00030342 DNC011151 Investigative Drug NABILONE
CFAMM00030228 DNC008781 Investigative Drug KM-233

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21794 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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