CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD180
Family Name Lipoprotein lipase Inhibitor Gemfibrozil Family
No. of Seeds 1 No. of Other Members 28
Family Centroid CFAMM00030787 Functional Category Approved Drug with Human Metabolite
Superfamily Lipoprotein lipase Inhibitor Gemfibrozil Superfamily
Class Class 164

Cousin Family NamesSeedsMembers
Prostaglandin F2-alpha receptor ligand prostaglandin analog Tr... 4 35
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 3-ben... 4 74
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 6-meth... 2 36
Aromatase Inhibitor 3,4-bis(3,4-dimethoxyphenyl)furan-2(5h)-on... 4 86
Hormone-sensitive lipase Inhibitor 2-(3-methoxybenzylthio)-2-p... 1 19
Histone deacetylase 2 and Histone deacetylase 8 inhibitor AC1L... 2 2
Glutamate carboxypeptidase 2 inhibitor SureCN5486002 family 1 1
Free fatty acid receptor 1 ligand 3-[4-[2-[3-(trifluoromethoxy... 1 0
Cytosolic phospholipase A2 beta inhibitor 5-[3-(4-decoxyphenox... 2 15
Neuropeptide Y receptor type 5 and Thioredoxin glutathione red... 13 6
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
Thyroid hormone receptor beta and Thyroid hormone receptor alp... 1 1
Benzoxepines Metabolite 4,5-Dihydro-1-benzoxepin-3(2H)-one Family 1 2
Putative NP ZINC04043753 Family 8 6
benzofuran-2-one NP 5-hydroxybenzofuran-2(3h)-one Family 1 0
2-(2-methoxyphenyl)-5-oxooxolane-3-carboxylate NP ZINC00132596... 4 2
3-pentyl-5-(phenoxymethyl)oxolan-2-one NP ZINC02116245 Family 4 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00030787 DAP000210 Approved Drug Gemfibrozil

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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