CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD187
Family Name 5-hydroxytryptamine receptor Ligand Ramosetron Family
No. of Seeds 10 No. of Other Members 219
Family Centroid CFAMM00033485 Functional Category Approved Drug with Natural Product
Superfamily 5-hydroxytryptamine receptor Ligand Ramosetron Superfamily
Class Class 170

Cousin Family NamesSeedsMembers
Leutinizing-hormone-releasing hormone inhibitor peptide Leupro... 43 911
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Delavirdine Family 1 68
Reverse transcriptase Inhibitor Nevirapine Family 23 640
5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family 7 460
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Tubulin beta chain Inhibitor Mebendazole Family 12 84
Histamine H1 receptor Ligand Mizolastine Family 14 603
Prothrombin Inhibitor Dabigatran Family 7 182
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Purine nucleoside phosphorylase Inhibitor BCX-34 Family 2 31
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Growth hormone receptor Ligand EP-51216 Family 34 390
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
NS5A protein Inhibitor Bms 790052 Family 5 9
BIBT986 family 7 96
IPI-145 family 2 4
SB989 family 17 91
Histone deacetylase Inhibitor JNJ-26481585 Family 2 5
Vascular endothelial growth factor receptor 1 and Angiopoietin... 29 127
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
PHA848125 family 13 138
CC-486 family 7 103
JAK Inhibitor Momelotinib Family 33 83
Vascular endothelial growth factor receptor 2 Ligand XL999 Family 11 87
Lethal factor Inhibitor GM6001 Family 50 435
XL-888 family 16 85
Platelet activating factor, putative Inhibitor ABT-491 Family 22 62
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Somatostatin receptor type 2 Ligand L-054852 Family 13 88
D(4) dopamine receptor Ligand L-745,870 Family 30 205
5-hydroxytryptamine receptor 2B Ligand Sb 206553 Family 14 21
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 45
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[n... 12 10
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Serine/threonine-protein kinase Chk1 Inhibitor Granulatimide F... 1 1
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 2 3
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 4 33
Adenosine receptor A1 and Adenosine receptor A2a Ligand OSIP-3... 4 31
Telomerase reverse transcriptase Inhibitor NSC-745794 Family 3 1
Serine/threonine-protein kinase mTOR Inhibitor 4-(2-(1h-indol-... 2 15
Type-1 angiotensin II receptor Ligand [sar1,tdf3]angii Family 135 2
Glycogen synthase kinase-3 beta Inhibitor N-(8-(3-cyanophenyl)... 1 0
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand N-(9h-... 5 2
Proto-oncogene tyrosine-protein kinase Src Inhibitor 5,7-diphe... 2 11
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Glutamate receptor 1 Ligand Piriqualone Family 8 67
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Herpes simplex virus type 1 thymidine kinase Inhibitor N2-(3-t... 1 2
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Acetylcholinesterase and Cholinesterase Inhibitor 3-(2-diethyl... 12 160
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Histone deacetylase Inhibitor ST-5732 Family 8 6
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 2
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 2 4
Prothrombin inhibitor SureCN5856722 family 3 16
Orexin receptor type 2 and Orexin receptor type 1 ligand [(7R)... 10 10
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-amin... 10 48
Mu-type opioid receptor and Mu-type opioid receptor ligand Sur... 5 10
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA4D family 1 0
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 3 12
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 12
Poly [ADP-ribose] polymerase 1 inhibitor 2-(3-chlorophenyl)-1H... 4 38
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07ZE3... 6 1
Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family 3 6
Platelet-activating factor receptor ligand SureCN9384429 family 11 3
RAC-alpha serine/threonine-protein kinase inhibitor SureCN4728... 11 6
Macrophage colony-stimulating factor 1 receptor ligand SureCN1... 28 9
Macrophage colony-stimulating factor 1 receptor and Cytochrome... 13 3
Platelet-activating factor receptor ligand 5-methyl-2-[4-(2-me... 1 2
Transient receptor potential cation channel subfamily V member... 1 4
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Cannabinoid receptor 2 ligand AGN-PC-080WIY family 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 11
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
Cathepsin K and Potassium voltage-gated channel subfamily H me... 4 7
Serine/threonine-protein kinase pim-3 and Serine/threonine-pro... 4 6
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Mitogen-activated protein kinase 14 inhibitor N-cyclopropyl-4-... 4 10
RAC-alpha serine/threonine-protein kinase and Proline-rich AKT... 2 4
Adenosine receptor A2a ligand AGN-PC-01LVXW family 2 25
Adenosine receptor A2a ligand SureCN14156209 family 3 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M4U... 4 5
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-09M45... 8 1
Cell division cycle 7-related protein kinase and Cyclin-depend... 2 9
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Type-1 angiotensin II receptor and Type-2 angiotensin II recep... 3 6
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Coagulation factor X and Trypsin-1 inhibitor 2-(5-carbamimidoy... 5 2
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 1
5-hydroxytryptamine receptor 4 ligand 6-chloro-N-[[1-(2-methyl... 10 19
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 4 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 6 2
Inositol monophosphatase 1 and 15-hydroxyprostaglandin dehydro... 1 0
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 1
Renin and Cathepsin D inhibitor tert-butyl N-[(2S)-1-[[(2S)-1-... 2 2
Gonadotropin-releasing hormone receptor ligand 1-(7-azabicyclo... 4 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 1 1
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Insulin-like growth factor 1 receptor ligand AGN-PC-09QGLU family 3 1
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Platelet-activating factor receptor ligand SureCN7491834 family 28 15
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 2 2
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 18 3
Cannabinoid receptor 2 ligand AGN-PC-0A9SMV family 1 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 0
Tyrosine-protein kinase ITK/TSK and Receptor-type tyrosine-pro... 1 0
MAP kinase-activated protein kinase 2 inhibitor AGN-PC-0A9QGC ... 14 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 15 7
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801305 ... 2 0
Mitogen-activated protein kinase 9 and MAP kinase-activated pr... 1 0
Mitogen-activated protein kinase 14 inhibitor N-ethyl-5-methyl... 17 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 13 3
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 2 0
Renin inhibitor [2-[(3-fluoro-2-methylphenyl)methyl]-6-methyl-... 2 1
Coagulation factor X and Prothrombin inhibitor 2-carboxyindole... 2 8
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 14 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK3 ... 2 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Cytochrome P450 2D6 and Cytochrome P450 2C19 inhibitor Demethy... 1 4
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 2 1
Histamine H1 receptor and Histamine H4 receptor ligand [4-[2-[... 1 1
Heat shock protein HSP 90-beta inhibitor N-[(9R)-4-(3H-imidazo... 1 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
MAP kinase-activated protein kinase 2 inhibitor 4-fluoro-N-[4-... 25 1
Coagulation factor X inhibitor SureCN8289965 family 4 5
Ribosomal protein S6 kinase alpha-3 inhibitor N-(3-ethylimidaz... 2 2
3-phosphoinositide-dependent protein kinase 1 and RAC-alpha se... 10 4
Delta-type opioid receptor ligand ethyl N-[3-[(R)-[4-[ethyl(me... 2 6
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Dipeptidyl peptidase 4 and Potassium voltage-gated channel sub... 9 0
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor 6-[(3... 10 0
Aurora kinase B and Cyclin-dependent kinase 1 inhibitor 7-cycl... 3 16
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 3
Mast/stem cell growth factor receptor Kit and Mitogen-activate... 4 2
Casein kinase II subunit alpha and Serine/threonine-protein ki... 1 5
Insulin-like growth factor 1 receptor and Mitogen-activated pr... 3 4
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Prothrombin and Cationic trypsin inhibitor (2S)-1-[(2R)-3,3-di... 5 9
Protein kinase C theta type and Leucine-rich repeat serine/thr... 1 1
Heat shock protein HSP 90-beta inhibitor 1-(2-amino-4-methylqu... 1 2
Serine/threonine-protein kinase TBK1 and Inhibitor of nuclear ... 1 0
Vascular endothelial growth factor receptor 2 ligand (3Z)-3-[5... 4 11
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Dipeptidyl peptidase 4 inhibitor 2-[[2-[(3R)-3-aminopiperidin-... 1 0
Aurora kinase A and Aurora kinase B inhibitor [4-[[7-cyclopent... 6 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Glycogen synthase kinase-3 beta inhibitor N-[2-[4-(ethylsulfon... 3 1
Glycogen synthase kinase-3 beta inhibitor 2-(4-fluorophenyl)-N... 4 2
Type-1 angiotensin II receptor ligand 7-methyl-N-(2-phenylethy... 2 10
DNA gyrase subunit B inhibitor 5-[2-(ethylcarbamoyl)-4-[3-(tri... 2 4
Cyclin-dependent kinase 2 and Serine/threonine-protein kinase ... 2 2
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
Somatostatin receptor type 3 ligand tert-butyl 4-[(3R)-3-(5-ph... 2 2
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 2 0
Growth hormone secretagogue receptor type 1 ligand SureCN36660... 4 14
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(1-phenylimidaz... 2 1
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152412 family 8 0
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family 16 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 1
Metabotropic glutamate receptor 5 ligand 5-methyl-N-(4-methyl-... 1 2
Smoothened homolog inhibitor N-[4-methyl-3-(5-phenyl-1H-imidaz... 1 0
Eukaryotic translation initiation factor 2-alpha kinase 3 inhi... 11 2
Cdc2-related kinase inhibitor N-[6-(3,5-dimethylphenyl)-1-meth... 1 0
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Somatostatin receptor type 3 and Somatostatin receptor type 4 ... 5 1
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206058 family 5 0
P2X purinoceptor 7 inhibitor SureCN109432 family 10 28
P2X purinoceptor 7 inhibitor SureCN113576 family 2 1
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
CGMP-dependent protein kinase inhibitor SureCN14561191 family 4 0
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 1 0
Dipeptidyl peptidase 4 inhibitor 2-[(3R)-3-aminopiperidin-1-yl... 3 4
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 3 0
Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2 ... 16 0
Glycogen synthase kinase-3 beta inhibitor 3-(5-bromo-1-methyli... 1 0
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 10 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-pheny... 9 2
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 8
Orexin receptor type 2 and Orexin receptor type 1 ligand SureC... 2 0
C-C chemokine receptor type 5 ligand N-[3-[4-[3-cyclohexyl-5-(... 5 4
Eukaryotic translation initiation factor 2-alpha kinase 3 and ... 4 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 4-[4... 1 1
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 3
Histone deacetylase 1 inhibitor 1-methyl-N-[(1S)-7-oxo-1-(5-qu... 2 1
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Somatostatin receptor type 1 and Somatostatin receptor type 2 ... 3 0
RAF proto-oncogene serine/threonine-protein kinase and Serine/... 4 3
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Proteinase-activated receptor 1 and Prothrombin ligand (2S)-N-... 3 23
Platelet-derived growth factor receptor beta and Vascular endo... 1 0
Glycogen synthase kinase-3 beta inhibitor GSK-3beta Inhibitor ... 1 0
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[[3-(2-aminoet... 8 7
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Platelet-activating factor receptor ligand (1-ethylindol-3-yl)... 17 13
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 3 0
Alpha-1B adrenergic receptor and Alpha-1A adrenergic receptor ... 2 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 2
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 2 0
Type-1 angiotensin II receptor ligand 2-[(2-ethyl-5,7-dimethyl... 5 3
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 1 1
KiSS-1 receptor ligand SureCN5132924 family 2 4
Gamma-aminobutyric acid receptor subunit pi and Gamma-aminobut... 4 0
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 5 1
Cell division cycle 7-related protein kinase inhibitor Pyrrolo... 2 6
Epidermal growth factor receptor ligand (E)-5-[4-(3-bromoanili... 11 0
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 0
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... 3 2
Melanin-concentrating hormone receptor 1 ligand SureCN3834858 ... 2 1
Melanocortin receptor 3 and Melanocyte-stimulating hormone rec... 2 3
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 2 0
Dipeptidyl peptidase 4 inhibitor SureCN5776796 family 1 0
Egl nine homolog 1 inhibitor 2-[(1,6-diphenylimidazo[4,5-c]pyr... 1 5
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1
Tyrosine-protein kinase Lck inhibitor (3S)-3-[(1S)-1-[[4-(benz... 14 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor 2-[4-(5-sulfanylidene... 1 1
LIM domain kinase 2 inhibitor 3-[[(cyanoamino)-[(2S)-2-methyl-... 6 0
Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymeras... 4 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-077DC5 family 2 2
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor AGN-PC-07B2Q... 6 0
Neuropeptide Y receptor type 5 ligand SureCN8149543 family 1 0
Cannabinoid receptor 2 ligand [(4S,4aR,8aS)-4-hydroxy-4-phenyl... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935256 family 1 0
Mitogen-activated protein kinase kinase kinase 5 inhibitor 4-(... 2 0
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 inhibit... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00033485 DNAP001401 Approved Drug Ramosetron
CFAMM00033369 DAP000221 Approved Drug Ondansetron
CFAMM00033459 DAP000369 Approved Drug Alosetron
CFAMM00033393 CHEMBL325422 Bioactive (1-methyl-1h-indol-3-yl)(4,5,6,7-tetrahydro-1h-benzimidazol-5-yl)methanon
CFAMM00033376 CHEMBL1628632 Bioactive 3-(5-methyl-1H-imidazol-4-yl)-1-[1-(tritritiomethyl)indol-3-yl]propan-1-one
CFAMM00033571 CHEMBL122903 Bioactive 3-(5-methyl-1H-imidazol-4-yl)-1-(1-methylindol-3-yl)propan-1-one
CFAMM00033444 CHEMBL421424 Bioactive CHEMBL421424
CFAMM00033466 CHEMBL1628655 Bioactive [3H]ramosetron
CFAMM00033450 CHEMBL333737 Bioactive AGN-PC-02KNO4
CFAMM00033528 DNC008556 Investigative Drug (R)-ONDANSETRON

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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