CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Alpha-2 adrenergic receptor Ligand Clonidine Family
No. of Seeds 4 No. of Other Members 20
Family Centroid CFAMM00035476 Functional Category Approved Drug
Superfamily Alpha-2 adrenergic receptor Ligand Clonidine Superfamily
Class Class 175

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Proguanil Family 8 46
Metabotropic glutamate receptor 5 Ligand Mcn3377 Family 1 12
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 1 2
Nischarin and Alpha-2A adrenergic receptor ligand N-(2-chloro-... 1 2
5-hydroxytryptamine receptor 3E and 5-hydroxytryptamine recept... 1 0


External ID

Functional Category

Molecule Name

CFAMM00035476 DAP000231 Approved Drug Clonidine
CFAMM00035475 DAP000236 Approved Drug Apraclonidine
CFAMM00035472 CHEMBL2058631 Bioactive N-(2,6-dichlorophenyl)-5-methyl-4,5-dihydro-1H-imidazol-2-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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