CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Benzodiazepine receptor Ligand Alprazolam Family
No. of Seeds 4 No. of Other Members 35
Family Centroid CFAMM00036299 Functional Category Approved Drug with Human Metabolite
Superfamily Benzodiazepine receptor Ligand Alprazolam Superfamily
Class Class 180

Cousin Family NamesSeedsMembers
Benzodiazepine receptor Ligand Midazolam Family 5 160
Alpha adrenergic receptor Ligand Dapiprazole Family 1 7
Gamma-aminobutyric acid receptor Ligand Pitrazepine Family 1 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 2
Adenosine receptor A2b and Adenosine receptor A2a ligand CP-66... 3 33
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Nuclear rec... 9 6
Vasopressin V1a receptor and Vasopressin V2 receptor ligand 8-... 6 2
Cholecystokinin receptor type A and Gastrin/cholecystokinin ty... 1 0
Progesterone receptor and Cytochrome P450 2C19 ligand AGN-PC-0... 8 3
Platelet-activating factor receptor ligand 6-(2-fluorophenyl)-... 1 0


External ID

Functional Category

Molecule Name

CFAMM00036294 DAP000930 Approved Drug Estazolam
CFAMM00036329 DAP000244 Approved Drug Triazolam
CFAMM00036299 DAP000239 Approved Drug Alprazolam
CFAMM00036305 DAP001251 Approved Drug Adinazolam

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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