CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Beta-2 adrenergic receptor ligand catecholamine Orciprenaline Family
No. of Seeds 13 No. of Other Members 13
Family Centroid CFAMM00036545 Functional Category Approved Drug
Superfamily adrenergic receptor ligand catecholamine Superfamily
Class Class 62

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Alpha adrenergic receptor Ligand Pseudoephedrine Family 4 96
Dopamine receptor ligand L-Tyrosine derivative Levodopa Family 4 59
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
Beta-2 adrenergic receptor Ligand Bambuterol Family 4 9
D(1A) dopamine receptor Ligand Fenoldopam Family 4 78
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Alpha-1B adrenergic receptor ligand Phenylephrine analog Metho... 9 56
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Zucapsacin family 7 177
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
Muscarinic acetylcholine receptor M1 Ligand GSK573719 Family 2 0
D(3) dopamine receptor Ligand U-99194A Family 7 33
Vernakalant family 1 1
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70... 16 27
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Arachidonate 5-lipoxygenase Inhibitor Bw A360C Family 12 8
M-phase inducer phosphatase 1 Inhibitor Naphthoquinone Analogs... 11 56
Fibroblast growth factor receptor Ligand SU5403 Family 8 8
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Lethal factor Inhibitor N-(3,4,5-trihydroxyphenethyl)oleamide ... 1 3
Sodium-dependent dopamine transporter Inhibitor Secocularidine... 3 9
Beta-2 adrenergic receptor and Beta-3 adrenergic receptor liga... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
D(2) dopamine receptor and D(1A) dopamine receptor ligand (2R,... 3 2
Muscarinic acetylcholine receptor M3 and Beta-2 adrenergic rec... 2 1
Mu-type opioid receptor and Kappa-type opioid receptor ligand ... 1 0
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
Phenylalanine--tRNA ligase alpha subunit inhibitor TCMDC-14030... 1 1


External ID

Functional Category

Molecule Name

CFAMM00036545 DAP000811 Approved Drug Orciprenaline
CFAMM00036542 DAP000946 Approved Drug Fenoterol
CFAMM00036568 DAP000246 Approved Drug Terbutaline
CFAMM00036560 CHEMBL1800936 Bioactive 5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-hydroxyphenyl)butan-2-yl]amino]ethyl]benzene-1,3-diol
CFAMM00036562 CHEMBL2426777 Bioactive N-Cyclopentylbutanephrine
CFAMM00036537 CHEMBL1160544 Bioactive Terbutaline sulfate
CFAMM00036541 DNC007436 Investigative Drug (R,S)-(-)-fenoterol
CFAMM00036540 DNC007435 Investigative Drug (S,R)-(+)-fenoterol
CFAMM00036539 DNC007434 Investigative Drug (R,R)-(-)-fenoterol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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