CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD205
Family Name Beta-2 adrenergic receptor Ligand Formoterol Family
No. of Seeds 16 No. of Other Members 63
Family Centroid CFAMM00036659 Functional Category Approved Drug with Human Metabolite
Superfamily Beta-2 adrenergic receptor Ligand Formoterol Superfamily
Class Class 182

Cousin Family NamesSeedsMembers
Beta-2 adrenergic receptor Ligand Procaterol Family 7 42
Beta-2 adrenergic receptor Ligand Olodaterol Family 16 27
D(2) dopamine receptor Ligand Ar-c68397aa Family 18 81
Beta-3 adrenergic receptor Ligand Cgp 12177 Family 3 8
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor Liga... 40 90
Amyloid beta A4 protein Inhibitor SB-13 Family 1 2
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Beta-3 adrenergic receptor Ligand BMS-196085 Family 18 72
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Tyrosinase Inhibitor 1-(4-(benzyloxy)phenyl)-3-hydroxyurea Family 9 23
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 5 16
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 5
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 1
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 20 7
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 5 13
Beta-1 adrenergic receptor ligand 1-[2-[[(2S)-3-(2-cyanophenox... 10 4
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 2
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Beta-2 adrenergic receptor ligand SureCN5041910 family 12 1
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 2 3
Beta-3 adrenergic receptor ligand N-[5-[2-[[1-[4-[(Z)-(2-amino... 5 2
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Beta-2 adrenergic receptor ligand 4-[2-[2-[4-[[2-(4-chlorophen... 1 1
Beta-2 adrenergic receptor ligand 4-[2-[2-[4-[[2-(2,5-dimethox... 1 1
Beta-3 adrenergic receptor ligand N-[5-[(3R)-4-[[(1R)-1-(3,4-d... 1 0
Beta-3 adrenergic receptor ligand (2S)-N-(4-chlorophenyl)-2-[[... 1 8
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 3 6
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 8 0
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 0
D(3) dopamine receptor ligand SureCN2078708 family 1 0
Beta-3 adrenergic receptor and Beta-2 adrenergic receptor liga... 1 1
Estrogen receptor and Histone deacetylase 6 ligand N-[4-[[2-[4... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00036659 DAP000247 Approved Drug Formoterol
CFAMM00036580 DAP000943 Approved Drug Arformoterol
CFAMM00036575 CHEMBL1200811 Bioactive FORMOTEROL FUMARATE
CFAMM00036660 CHEMBL2133469 Bioactive eformoterol
CFAMM00036651 CHEMBL605993 Bioactive Foradil
CFAMM00036573 CHEMBL363260 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-(2-phenylethoxy)phenyl]ethylamino]ethyl]phenyl]formamide
CFAMM00036608 CHEMBL185052 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-(4-phenylbutoxy)phenyl]ethylamino]ethyl]phenyl]formamide
CFAMM00036579 CHEMBL1951071 Bioactive Arformoterol tartrate
CFAMM00036607 CHEMBL440561 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[3-(4-phenylbutoxy)phenyl]ethylamino]ethyl]phenyl]formamide
CFAMM00036593 CHEMBL363329 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[4-(3-phenylpropoxy)phenyl]ethylamino]ethyl]phenyl]formamide
CFAMM00036606 CHEMBL183948 Bioactive N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[2-[3-(3-phenoxypropoxy)phenyl]ethylamino]ethyl]phenyl]formamide
CFAMM00036591 DNCL002794 Clinical Trial Drug Aclidinium/formoterol
CFAMM00036645 DCL000563 Clinical Trial Drug Milveterol
CFAMM00036626 DCL000822 Clinical Trial Drug GSK-159797
CFAMM00036588 DCL000501 Clinical Trial Drug Budesonide & formoterol fumarate dihydrate
CFAMM00036655 DNCL002055 Clinical Trial Drug Mometasone furoate/ formoterol fumarate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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