CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD210
Family Name Alpha adrenergic receptor ligand phenothiazine derivative Thioridazine Family
No. of Seeds 4 No. of Other Members 10
Family Centroid CFAMM00036881 Functional Category Approved Drug with Human Metabolite
Superfamily Biogenic amine receptor, Calmodulin binding phenothiazine Superfamily
Class Class 32

Cousin Family NamesSeedsMembers
Calmodulin inhibitor phenothiazine derivative Trifluoperazine ... 3 30
D(2) dopamine receptor Ligand phenothiazine analog Prochlorper... 4 25
Muscarinic acetylcholine receptor M5 ligand phenothiazine deri... 8 37
Histamine H1 receptor ligand phenothiazine derivative Mequitaz... 3 2
5-hydroxytryptamine receptor 6 Ligand 4-(4-benzenesulfonamidop... 4 5
Cholinesterase Inhibitor N-cyclohexyl-1'h-phenothiazine-1'-car... 7 2
Sigma non-opioid intracellular receptor 1 ligand 3-[4-(azepan-... 8 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00036883 DAP000315 Approved Drug Thiethylperazine
CFAMM00036881 DAP000476 Approved Drug Thioridazine
CFAMM00036885 DAP000252 Approved Drug Mesoridazine
CFAMM00036895 CHEMBL611207 Bioactive 10-[2-[(2R)-1-methylpiperidin-2-yl]ethyl]-2-methylsulfinylphenothiazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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