CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD211
Family Name D(1A) dopamine receptor Ligand Fenoldopam Family
No. of Seeds 4 No. of Other Members 78
Family Centroid CFAMM00036980 Functional Category Approved Drug
Superfamily D(1A) dopamine receptor Ligand Fenoldopam Superfamily
Class Class 185

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand catecholamine Dopamine family 9 170
Noradrenergic re-uptake and Serotonin re-uptake inhibitor bicy... 6 375
Beta adrenergic receptor ligand catecholamine group Isoprotere... 7 130
Opioid receptor ligand opiate Levorphanol Family 18 537
Alpha adrenergic receptor ligand catecholamine Phenylephrine F... 4 39
Alpha-2 adrenergic receptor Ligand Oxymetazoline Family 5 4
Beta-2 adrenergic receptor ligand catecholamine Orciprenaline ... 13 13
Beta-2 adrenergic receptor ligand catecholamine Salbutamol Family 10 90
D(1B) dopamine receptor Ligand Apomorphine Family 30 271
Muscarinic acetylcholine receptor M3 Ligand Tolterodine Family 8 171
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Kappa-type opioid receptor Ligand Dezocine Family 36 46
Noradrenergic re-uptake Inhibitor Desvenalfaxine Succinate Family 2 4
Zucapsacin family 7 177
Eptazocine Hbr family 6 8
Noradrenergic re-uptake and Opioid receptor Ligand Tapentadol ... 21 79
CORT-108297 family 46 44
5-hydroxytryptamine receptor 1A Ligand (s)-uh-301 Family 35 20
D(2) dopamine receptor and D(1A) dopamine receptor Ligand A-70... 16 27
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 6 40
Acetylcholinesterase and Cholinesterase Inhibitor N,n'-(1',10'... 12 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 9 16
Squalene synthase Inhibitor 3-[7'-(methoxy)-napht-2'-yl]-quinu... 53 30
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 44 3
D(2) dopamine receptor and D(1A) dopamine receptor Ligand SK&F... 8 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 9
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 3 4
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 1 2
Tubulin beta chain Inhibitor Colchinol Family 3 109
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TF5... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
D(2) dopamine receptor and D(1A) dopamine receptor ligand (2R,... 3 2
D(1A) dopamine receptor ligand (5S)-5-(4-azidophenyl)-8-iodo-3... 2 0
D(1A) dopamine receptor ligand (5R)-8-bromo-3-methyl-5-phenyl-... 6 15
Matrix metalloproteinase-9 and 72 kDa type IV collagenase inhi... 2 4
D(1A) dopamine receptor and D(2) dopamine receptor ligand Biom... 3 1
Sodium-dependent dopamine transporter and Sodium-dependent ser... 1 0
5-hydroxytryptamine receptor 2C ligand (3aS,4R,8bS)-6-chloro-7... 1 4
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 1 0
D(1A) dopamine receptor and D(1B) dopamine receptor ligand Sur... 6 6
D(1A) dopamine receptor and D(2) dopamine receptor ligand (5R)... 2 0
D(1A) dopamine receptor and D(1B) dopamine receptor ligand (6a... 1 0
D(1A) dopamine receptor and D(1B) dopamine receptor ligand met... 1 1
D(1A) dopamine receptor and D(1B) dopamine receptor ligand N-[... 1 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 2
Alpha-2A adrenergic receptor and Alpha-1B adrenergic receptor ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00036980 DAP000254 Approved Drug Fenoldopam
CFAMM00036978 CHEMBL553503 Bioactive (+/-)-6-Chloro-PB hydrobromide
CFAMM00036946 DNC012467 Investigative Drug SCH-24518
CFAMM00036965 DNC001339 Investigative Drug SKF 38393

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21783 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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