CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Gamma-aminobutyric acid B receptor Ligand Baclofen Family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00037045 Functional Category Approved Drug with Natural Product
Superfamily Gamma-aminobutyric acid B receptor Ligand Baclofen Superfamily
Class Class 187

Cousin Family NamesSeedsMembers
Tyrosine 3-monooxygenase Inhibitor L-phenylalanine Family 19 144
ATP-sensitive inward rectifier potassium channel 10 Ligand Nat... 3 233
Chymase Inhibitor Phenylalanylmethane Family 1 8
Voltage-dependent calcium channel gamma-1 subunit Ligand 2-ami... 2 0
Glutamate receptor ionotropic, kainate 2 ligand (2S,3S,4S)-4-[... 14 2
Vasopressin V1a receptor ligand (2R)-3-(4-chlorophenyl)-2-[[2-... 6 2
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-3-... 1 5
Sodium-dependent dopamine transporter and Transporter inhibito... 1 1
Sodium- and chloride-dependent GABA transporter 1 inhibitor Su... 8 8
Glutamate receptor ionotropic, kainate 1 and Glutamate recepto... 1 1
Botulinum neurotoxin type A inhibitor (3R)-3-(2,4-dichlorophen... 1 0


External ID

Functional Category

Molecule Name

CFAMM00037045 DAP000257 Approved Drug Baclofen
CFAMM00037058 CHEMBL1256351 Bioactive Fenclonine
CFAMM00037039 DNCL003114 Clinical Trial Drug STX209
CFAMM00037041 DNC014636 Investigative Drug (R)-5-Amino-3-(4-chloro-phenyl)-pentanoic acid
CFAMM00037048 DNC014692 Investigative Drug 4-Amino-3-(2-chloro-phenyl)-butyric acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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