CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Lipoprotein lipase Inhibitor Clofibrate Family
No. of Seeds 3 No. of Other Members 28
Family Centroid CFAMM00038481 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Lipoprotein lipase Inhibitor Clofibrate Superfamily
Class Class 191

Cousin Family NamesSeedsMembers
Acetyl-CoA carboxylase 2 Inhibitor 2-[4-(2,4-dichlorophenoxy)p... 1 10
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 2 14
Prostaglandin D2 receptor 2 Ligand 2-(4-chloro-2-cyclohexylphe... 7 25
Prostaglandin D2 receptor 2 Ligand 2-(4-cyano-2-cyclohexylphen... 6 3
Prostaglandin G/H synthase 1 Inhibitor Acetic Acid 2-heptylsel... 1 14
4-hydroxyphenylpyruvate dioxygenase Inhibitor (4-hydroxy-pheno... 1 13
D-amino-acid oxidase inhibitor 5-hydroxy-2-(phenoxymethyl)pyra... 2 2
D-amino-acid oxidase inhibitor 2-[(4-chlorophenoxy)methyl]-5-h... 2 3
Benzo-p-Dioxins Metabolite 1,4-Benzodioxin-2(3H)-one Family 1 3
(3R,4S,5S)-2-(4-chlorophenoxy)-6-(iodomethyl)tetrahydro-2H-pyr... 3 0


External ID

Functional Category

Molecule Name

CFAMM00038481 DAP000262 Approved Drug Clofibrate
CFAMM00038449 DNC000630 Investigative Drug Etomoxir
CFAMM00038463 DNC000646 Investigative Drug Fibrates

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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