CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Mu-type opioid receptor ligand opiate Remifentanil Family
No. of Seeds 10 No. of Other Members 24
Family Centroid CFAMM00038524 Functional Category Approved Drug with Human Metabolite
Superfamily opioid receptor ligand opiate Remifentanil Alfentanil Superfamily
Class Class 193

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Motilin receptor Ligand GSK962040 Family 30 457
Tumor necrosis factor Inhibitor Pirfenidone Family 2 38
Serine/threonine-protein kinase mTOR Inhibitor CC-223 Family 12 135
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Mitogen-activated protein kinase 14 Inhibitor Dihydro-quinolin... 3 14
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 5 47
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Aldose reductase Inhibitor (4-methyl-2-oxo-2h-quinolin-1-yl)-a... 1 15
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 2 1
B2 bradykinin receptor ligand AGN-PC-074WA4 family 2 3
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 10 12
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 1 8
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 4 6
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 1
5-hydroxytryptamine receptor 7 ligand 3-ethyl-3-[4-[4-(4-fluor... 3 1
Mu-type opioid receptor ligand AGN-PC-00NCMY family 2 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand 1-[4... 1 0
5-hydroxytryptamine receptor 4 ligand 2-PIPERIDIN-1-YLETHYL PH... 1 3
Sodium- and chloride-dependent GABA transporter 1 and Sodium- ... 1 3
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0


External ID

Functional Category

Molecule Name

CFAMM00038524 DAP000264 Approved Drug Remifentanil
CFAMM00038498 CHEMBL2311157 Bioactive methyl 1-phenethyl-4-(N-propanoylanilino)piperidine-4-carboxylate
CFAMM00038495 CHEMBL81328 Bioactive AGN-PC-002JDJ
CFAMM00038506 CHEMBL200392 Bioactive 2-fluoranylethyl 1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
CFAMM00038512 CHEMBL371710 Bioactive methyl 1-(5-fluoranylpentyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
CFAMM00038505 CHEMBL200456 Bioactive fluoranylmethyl 1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
CFAMM00038514 CHEMBL178035 Bioactive AGN-PC-001OE8
CFAMM00038519 DNC003328 Investigative Drug Carfentanil
CFAMM00038521 DNC011480 Investigative Drug LOFENTANIL

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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