CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD226
Family Name Peroxisome proliferator-activated receptor gamma Ligand Pioglitazone Family
No. of Seeds 2 No. of Other Members 29
Family Centroid CFAMM00039868 Functional Category Approved Drug
Superfamily Peroxisome proliferator-activated receptor gamma Ligand Pioglitazone Superfamily
Class Class 198

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mepyramine Family 5 65
Amyloid beta A4 protein Inhibitor Florbetapir F-18 Family 8 265
Smoothened homolog Inhibitor LDE225 Family 3 76
5-hydroxytryptamine receptor 1A Ligand P-MPPI Family 33 81
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
Fatty-acid amide hydrolase 1 Inhibitor Pyridin-3-yl 4-butoxybe... 10 5
Nitric oxide synthase, inducible and Nitric oxide synthase, br... 2 3
Metabotropic glutamate receptor 5 Ligand 3-methoxy-n-(6-methyl... 3 15
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA5M family 4 14
Muscarinic acetylcholine receptor M2 and Muscarinic receptor 3... 4 3
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
5-hydroxytryptamine receptor 3A ligand 6-methyl-5-[4-[3-[(2R)-... 12 3
Histamine H3 receptor ligand 3-[4-[3-[(2R)-2-methylpyrrolidin-... 1 5
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(4-fluo... 7 1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cGMP-inhib... 18 10
Peroxisome proliferator-activated receptor gamma and Cytochrom... 1 1
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Free fatty acid receptor 1 ligand Cpd-B family 1 4
Matrilysin and 72 kDa type IV collagenase inhibitor (3S,6R,7S)... 2 2
Farnesyl pyrophosphate synthase inhibitor [phosphono-[[4-(4-pr... 6 0
Transient receptor potential cation channel subfamily V member... 2 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 2
Pol polyprotein inhibitor tert-butyl N-[(2S,3R)-3-hydroxy-4-[[... 1 1
5-(4-methoxyphenyl)-4-oxo-1H-pyrido[2,3-d]pyrimidin-2-olate NP... 1 0
4-[(4-pyridin-1-ium-2-ylpiperazin-1-yl)methyl]chromen-2-one NP... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00039860 DAP000271 Approved Drug Rosiglitazone
CFAMM00039868 DAP000272 Approved Drug Pioglitazone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21785 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543