CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin E2 receptor EP2 subtype Ligand Iloprost Family
No. of Seeds 2 No. of Other Members 37
Family Centroid CFAMM00039917 Functional Category Approved Drug with Human Metabolite
Superfamily Prostaglandin E2 receptor EP2 subtype Ligand Iloprost Superfamily
Class Class 199

Cousin Family NamesSeedsMembers
Prostaglandin E2 receptor EP2 subtype Ligand Alprostadil Family 11 127
Prostacyclin receptor Ligand Dinoprost Tromethamine Family 2 1
Prostacyclin receptor Ligand Epoprostenol Family 4 33
Unoprostone Isopropyl Ester family 1 3
Prostaglandin G/H synthase 2 Inhibitor Prostaglandin G2 Family 2 0


External ID

Functional Category

Molecule Name

CFAMM00039917 DAP000273 Approved Drug Iloprost
CFAMM00039919 CHEMBL494 Bioactive ILOPROST

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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