CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Prostaglandin F2-alpha receptor ligand prostaglandin analog Travoprost Family
No. of Seeds 4 No. of Other Members 35
Family Centroid CFAMM00039957 Functional Category Approved Drug
Superfamily Prostaglandin F2-alpha receptor ligand prostaglandin analog Travoprost Enprostil Sulprostone Superfamily
Class Class 200

Cousin Family NamesSeedsMembers
Lipoprotein lipase Inhibitor Gemfibrozil Family 1 28
Beraprost family 3 1
Enprostil family 1 2
Carbonic anhydrase 9 and Carbonic anhydrase 12 Inhibitor Ethox... 12 80
Kappa-type opioid receptor Ligand Anisocoumarin H Family 3 5
Prostaglandin F2-alpha receptor and Prostaglandin E2 receptor ... 2 8
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
3-pentyl-5-(phenoxymethyl)oxolan-2-one NP ZINC02116245 Family 4 0


External ID

Functional Category

Molecule Name

CFAMM00039957 DAP000274 Approved Drug Travoprost
CFAMM00039942 DNAP001264 Approved Drug Tafluprost
CFAMM00039970 CHEMBL185484 Bioactive UNII-WJ68R08KX9
CFAMM00039948 CHEMBL334398 Bioactive AC1NSK9T

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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