CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name Vitamin D3 receptor ligand Vitamin D analog Cholecalciferol Family
No. of Seeds 7 No. of Other Members 270
Family Centroid CFAMM00041730 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Vitamin D3 receptor ligand Vitamin D analog Superfamily
Class Class 165

Cousin Family NamesSeedsMembers
Vitamin D3 receptor ligand Vitamin D analog Calcitriol Family 49 120
Corticosteroid-binding globulin Inhibitor Rimexolone Family 6 138
Androgen receptor ligand anabolic androgenic steroid Testoster... 8 198
Progesterone receptor ligand steroidal progestin Medroxyproges... 6 20
Glucocorticoid receptor ligand corticosteroid Prednisone Family 2 1
Progesterone receptor Ligand Desogestrel Family 2 5
Trimegestone family 7 25
HE3286 family 5 34
Nuclear receptor subfamily 1 group I member 2 Ligand Pregnenol... 1 1
Lanosterol synthase Inhibitor Lanosterol Family 2 62
Nuclear receptor ROR-alpha Ligand Cholesterol-sulfate Family 1 0
Tyrosine-protein phosphatase non-receptor type 1 Ligand Uvaol ... 3 24
Farnesyltransferase beta subunit, putative and Protein farnesy... 1 2
DNA polymerase and Glycogen phosphorylase, muscle form Inhibit... 32 22
DNA topoisomerase 2-beta Inhibitor Lupeol Family 2 23
Prostaglandin G/H synthase 2 Inhibitor 8alpha,19-dihydroxylabd... 2 10
Acetylcholinesterase and Cholinesterase Inhibitor 24-ethylchol... 1 2
Sex hormone-binding globulin inhibitor (3R,5S,7R,8S,9R,10S,13S... 1 0
Estrogen receptor beta and Androgen receptor ligand (8R,9S,10S... 1 5
Vitamin D3 receptor ligand (2E,4R,6S)-2-[(2Z)-2-[(7aR)-1-[(2R)... 2 0
7-dehydrocholesterol reductase inhibitor [(3R)-3-[(3S,10R,13R)... 1 5
Potassium-transporting ATPase alpha chain 2 and Sodium/potassi... 1 0
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase and 7-dehydr... 1 0
Protein kinase C zeta type and Transcription factor p65 inhibi... 2 0
Prenol Lipids Metabolite 4a-Carboxy-4b-methyl-5a-cholesta-8,24... 4 0
Prenol Lipids Metabolite Zeaxanthin Family 10 4
Steroids and Steroid Derivatives Metabolite Cholesteryl acetat... 4 55
Prenol Lipids Metabolite Camelliol B Family 1 20
Prenol Lipids Metabolite Fasciculol C Family 1 8


External ID

Functional Category

Molecule Name

CFAMM00041822 DNAP001486 Approved Drug Secalciferol
CFAMM00041600 DAP000365 Approved Drug Dihydrotachysterol
CFAMM00041454 DAP000290 Approved Drug Calcidiol
CFAMM00041453 DAP000291 Approved Drug Ergocalciferol
CFAMM00041730 DAP001273 Approved Drug Cholecalciferol
CFAMM00041799 DNC000425 Investigative Drug Cholesterol
CFAMM00041546 DNC003289 Investigative Drug Cholesterol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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