CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD240
Family Name Sodium channel protein type 10 subunit alpha Ligand Tetracaine Family
No. of Seeds 6 No. of Other Members 166
Family Centroid CFAMM00042683 Functional Category Approved Drug with Human Metabolite & Natural Product
Superfamily Sodium channel lignad Chloroprocaine Tetracaine Superfamily
Class Class 108

Cousin Family NamesSeedsMembers
Sodium/potassium-transporting ATPase subunit alpha-1 Inhibitor... 1 10
Retinoic acid receptor alpha Ligand Tamibarotene Family 5 95
Prostaglandin G/H synthase 1 Inhibitor Mesalazine Family 2 30
Prostaglandin G/H synthase 2 Inhibitor Mefenamic Acid Family 7 137
Dopamine reuptake and Noradrenergic re-uptake Inhibitor Cocain... 13 136
Lipase Inhibitor Cetilistat Family 1 13
Histone deacetylase 1 and Tyrosine-protein kinase JAK2 Inhibit... 2 3
M402 family 1 16
Beta-lactamase Inhibitor 4-[(methylsulfonyl)amino]benzoic Acid... 1 7
Neuraminidase Inhibitor 4-(acetylamino)-3-amino Benzoic Acid F... 2 27
Tyrosine-protein phosphatase non-receptor type 1 Ligand 2-(oxa... 3 11
3-oxo-5-alpha-steroid 4-dehydrogenase 2 Inhibitor 4-[4-(benzyl... 2 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 17 50
Cholinesterase Inhibitor 4-[4-(benzyloxy)piperidino]butyl-4-ni... 1 7
Carbonic anhydrase 2 Inhibitor 4-(4-tert-butylbenzylideneamino... 3 15
Trypsin Inhibitor 2-(2-iodo-phenyl)-benzo[d][1,3]oxazin-4-one ... 1 16
Acrosin and Trypsin-1 inhibitor (4-methylphenyl) 4-(diaminomet... 10 13
Retinal dehydrogenase 1 and Menin inhibitor CHEMBL1507858 family 1 6
Sodium-dependent dopamine transporter inhibitor (1R,3S)-3-(4-a... 1 0
Dipeptidyl peptidase 4 inhibitor 2-cyanopyrrolidine 24b family 1 1
Sodium-dependent serotonin transporter and D(2) dopamine recep... 8 6
Ras guanyl-releasing protein 3 and Protein kinase C alpha type... 4 47
Sodium-dependent dopamine transporter inhibitor 2-(4-nitrophen... 2 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 4-[[1... 2 5
Protein farnesyltransferase subunit beta and Protein farnesylt... 2 4
Type-2 angiotensin II receptor ligand (2S)-4-(dipentylcarbamoy... 1 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 8
Phosphoethanolamine/phosphocholine phosphatase and Ras-related... 1 1
Casein kinase I isoform alpha inhibitor methyl (2Z)-3-oxo-2-(2... 1 0
Multidrug resistance protein 1 inhibitor [(2R,3S,4R)-4-[[(2S)-... 1 5
5-hydroxytryptamine receptor 6 ligand AGN-PC-00ADLV family 1 0
DNA polymerase beta and Nuclear receptor ROR-gamma ligand AN-3... 1 3
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 1 1
Prenol Lipids Metabolite alpha-Terpinyl anthranilate Family 1 4
NP Methyl 3-acetyl-4-oxo-1,4-dihydroquinoline-8-carboxylate Fa... 2 0
Putative NP ZINC35345693 Family 7 1
2-oxo-1H-quinoline-4-carboxylate NP ZINC19735150 Family 5 4
Putative NP ZINC03999141 Family 2 1
[[(2R,3R,4R)-2,3,4,5-tetraacetyloxypentanoyl]amino]benzoate NP... 3 0
Putative NP ZINC00192342 Family 2 1
Putative NP ZINC12659473 Family 5 0
Putative NP ZINC32123992 Family 1 0
Putative NP ZINC00849538 Family 4 1
NP Methyl 4-(2-(2-(hydroxymethyl)-5-methoxy-4-oxopyridin-1(4h)... 1 0
3-[(Z)-3-chlorobut-2-enyl]-2-methyl-4-oxo-1H-quinoline-6-carbo... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00042587 DAP000296 Approved Drug Procaine
CFAMM00042683 DAP001431 Approved Drug Tetracaine
CFAMM00042582 DAP000514 Approved Drug Benzonatate
CFAMM00042708 DAP001234 Approved Drug Benzocaine
CFAMM00042518 DNC010020 Investigative Drug methyl 4-(4-hydroxybenzylideneamino)benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21760 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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