CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD247
Family Name Beta adrenergic receptor Ligand Levobunolol Family
No. of Seeds 6 No. of Other Members 133
Family Centroid CFAMM00043639 Functional Category Approved Drug with Natural Product
Superfamily Adrenergic receptor ligand Propranolol Levobunolol Metipranolol Superfamily
Class Class 80

Cousin Family NamesSeedsMembers
Alpha-1 adrenergic receptor ligand arylethanolamine derivative... 4 37
Beta adrenergic receptor ligand naphthol derivative Propranolo... 11 218
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Beta-1 adrenergic receptor Ligand Esmolol Family 5 39
Beta-1 adrenergic receptor Ligand Metoprolol Family 29 90
Beta adrenergic receptor Ligand Metipranolol Family 5 1
Potassium voltage-gated channel subfamily H member 2 Ligand Am... 2 16
Sodium channel protein type 5 subunit alpha Ligand Dyclonine F... 6 174
Acetylcholinesterase Inhibitor Donepezil Family 23 242
Beta adrenergic receptor Ligand Dipivefrin Family 3 55
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Alpha adrenergic receptor Ligand Bevantolol Family 4 48
Muscarinic acetylcholine receptor Ligand Flavoxate Family 9 350
Beta-2 adrenergic receptor Ligand Salmeterol Xinafoate Family 9 51
5-hydroxytryptamine receptor 2A Ligand Sarpogrelate Family 2 15
Growth hormone secretagogue receptor type 1 Ligand TZP-101 Family 28 263
Extracellular calcium-sensing receptor Ligand Ronacaleret Family 2 9
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
5-hydroxytryptamine receptor 2A and Sodium-dependent serotonin... 2 5
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Tyrosine-protein phosphatase non-receptor type 1 Ligand PNU177... 1 5
Plasmepsin-2 Inhibitor PS-662477 Family 7 55
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Leukotriene B4 receptor 1 Ligand SC-51146 Family 6 315
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 14
Histamine H3 receptor Ligand A-349821 Family 49 228
Extracellular calcium-sensing receptor and Potassium voltage-g... 3 11
Cannabinoid receptor 1 Ligand N-(4-methoxyphenethyl)oleamide F... 10 36
Beta-2 adrenergic receptor Ligand Gnf-pf-1694 Family 4 70
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 4 10
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 8
Sodium-dependent dopamine transporter and Sigma non-opioid int... 7 5
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 2 18
Extracellular calcium-sensing receptor and Sodium-dependent no... 2 2
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 6 1
Multidrug resistance protein 1 inhibitor 1-[2-[(2R)-3-[4-(2,3-... 2 41
Hypoxia-inducible factor 1-alpha and Cytochrome P450 2D6 inhib... 1 2
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 1 0
Pol polyprotein inhibitor AGN-PC-075V7I family 7 1
Neuronal acetylcholine receptor subunit alpha-7 ligand 2,7-bis... 3 0
Beta-1 adrenergic receptor ligand N-[2-[[(2S)-3-(2-cyanophenox... 1 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand (5Z,8... 4 2
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 14 1
Histamine H3 receptor ligand SureCN7244264 family 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 5
Neprilysin and Angiotensin-converting enzyme inhibitor (2S)-2-... 1 0
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 1 3
Sodium-dependent noradrenaline transporter and Cytochrome P450... 11 2
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 3 2
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 4 0
Histamine H1 receptor and Cysteinyl leukotriene receptor 1 lig... 1 15
Reverse transcriptase/RNaseH inhibitor AC1L9WPU family 1 1
Trace amine-associated receptor 1 ligand SureCN13886619 family 1 1
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 2 1
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 3
2-[4-(6-methoxy-2-oxochromen-3-yl)phenoxy]acetamide NP (s)-n-(... 7 0
3-methyl-4-oxo-2-phenylchromene-8-carboxamide NP N-(1,3-dihydr... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00043634 DAP000497 Approved Drug Propafenone
CFAMM00043639 DAP000303 Approved Drug Levobunolol
CFAMM00043555 CHEMBL482397 Bioactive AGN-PC-04Y2VA
CFAMM00043553 CHEMBL281294 Bioactive ethyl 2-[3-(tert-butylamino)-2-hydroxypropoxy]benzoate
CFAMM00043613 CHEMBL1201063 Bioactive PROPAFENONE HYDROCHLORIDE
CFAMM00043625 CHEMBL132196 Bioactive 1-[4-[2-hydroxy-3-(propan-2-ylamino)propoxy]-3-prop-2-enylphenyl]butan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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