CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD250
Family Name Calcium channel ligand dihydropyridine derivative Nisoldipine Family
No. of Seeds 18 No. of Other Members 94
Family Centroid CFAMM00043918 Functional Category Approved Drug
Superfamily Calcium channel ligand dihydropyridine derivative Nisoldipine Nicardipine Superfamily
Class Class 212

Cousin Family NamesSeedsMembers
Calcium channel ligand dihydropyridine derivative Nicardipine ... 10 16
Voltage-dependent L-type calcium channel subunit alpha-1F and ... 4 17
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 1 0
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 1 10
Nuclear receptor ROR-gamma and Huntingtin ligand CHEMBL1456749... 1 12
Voltage-dependent L-type calcium channel subunit alpha-1C liga... 2 3
Voltage-dependent L-type calcium channel subunit alpha-1F and ... 7 1
Voltage-dependent L-type calcium channel subunit alpha-1C and ... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00043918 DAP000595 Approved Drug Nisoldipine
CFAMM00043980 DAP000529 Approved Drug Nifedipine
CFAMM00043970 DAP000306 Approved Drug Nimodipine
CFAMM00043904 DAP001263 Approved Drug Nitrendipine
CFAMM00043932 CHEMBL599337 Bioactive 3-O-methyl 5-O-pentyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CFAMM00043987 CHEMBL2092919 Bioactive 8-[(4R)-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl]oxyoctyl-trimethylazanium;iodide
CFAMM00043931 CHEMBL599336 Bioactive 3-O-methyl 5-O-pentyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
CFAMM00043998 CHEMBL592155 Bioactive AGN-PC-068M7S
CFAMM00043929 CHEMBL1098840 Bioactive AGN-PC-07ZEYB
CFAMM00043961 CHEMBL1097880 Bioactive AGN-PC-07ZET8
CFAMM00043935 CHEMBL1096501 Bioactive AGN-PC-07ZEYA
CFAMM00043874 CHEMBL1094740 Bioactive AGN-PC-00M8YS
CFAMM00043965 CHEMBL1094406 Bioactive 2-Chloromethyl-3,5-dicarboethoxy-4-(m-nitrophenyl)-6-methyl-1,4-dihydropyridine
CFAMM00043909 CHEMBL1098856 Bioactive AGN-PC-07ZEYD
CFAMM00043889 CHEMBL1098210 Bioactive AGN-PC-07ZEV4
CFAMM00043945 DNCL001956 Clinical Trial Drug ARC029
CFAMM00043911 DCL000288 Clinical Trial Drug Cilnidipine
CFAMM00043982 DNC014337 Investigative Drug MEBUDIPINE

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

21767 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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