CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFAD251
Family Name Cannabinoid receptor 1 Ligand Rimonabant Family
No. of Seeds 20 No. of Other Members 260
Family Centroid CFAMM00044221 Functional Category Approved Drug
Superfamily Cannabinoid receptor 1 Ligand Rimonabant Superfamily
Class Class 213

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Cannabinoid receptor 1 Ligand TM38837 Family 20 15
Fibroblast growth factor receptor 2 Ligand Interferon Alfa (if... 14 162
Cannabinoid receptor 2 Ligand SR144528 Family 3 4
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Cannabinoid receptor 1 ligand AGN-PC-04YSUM family 7 6
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 1 2
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor 2-... 18 2
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 19
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 2 1
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 8 0
Cannabinoid receptor 1 ligand 5-(4-chlorophenyl)-1-(2,4-dichlo... 1 0
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 3
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Cannabinoid receptor 1 ligand SureCN4819820 family 11 5
Cannabinoid receptor 1 and Peroxisome proliferator-activated r... 2 5
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Coagulation factor X inhibitor SureCN8169809 family 12 18
Cannabinoid receptor 1 ligand SureCN4454684 family 2 0
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 6
Metabotropic glutamate receptor 5 ligand 5-(4-chlorophenyl)-1,... 3 1
Serine/threonine-protein kinase Chk1 inhibitor PDK1 inhibitor,... 1 4
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
Progesterone receptor ligand AGN-PC-00OK6G family 7 8
Cannabinoid receptor 1 ligand AGN-PC-07NHJ5 family 9 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 3 22
Cannabinoid receptor 1 ligand AGN-PC-07R5TU family 11 0
Cannabinoid receptor 1 ligand AGN-PC-07NHI2 family 4 1
Cannabinoid receptor 1 ligand AGN-PC-07R6O8 family 5 2
Cannabinoid receptor 1 ligand AGN-PC-07RA6C family 21 2
Cannabinoid receptor 1 ligand AGN-PC-07RA3R family 15 0
Cannabinoid receptor 1 ligand SureCN3822127 family 5 0
Cannabinoid receptor 1 ligand 1-(2-chlorophenyl)-5-(4-chloroph... 2 0
Cannabinoid receptor 1 ligand AGN-PC-07R6QS family 5 0
Cannabinoid receptor 1 ligand AGN-PC-07R9T4 family 27 0
Cannabinoid receptor 1 ligand AGN-PC-07R61A family 1 0
Cannabinoid receptor 1 and Translocator protein ligand AGN-PC-... 1 9


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00044221 DAP000307 Approved Drug Rimonabant
CFAMM00044033 CHEMBL2448073 Bioactive 5-(4-cyclobutylphenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide;hydrochloride
CFAMM00044005 CHEMBL563081 Bioactive AGN-PC-04VC6W
CFAMM00044207 CHEMBL511907 Bioactive 4-tert-butyl-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-piperidin-1-ylpyrazole-3-carboxamide
CFAMM00044249 CHEMBL484505 Bioactive 5-(4-chloro-2-methylphenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
CFAMM00044031 CHEMBL559655 Bioactive SureCN4589412
CFAMM00044117 CHEMBL541216 Bioactive AGN-PC-00BXNU
CFAMM00044268 CHEMBL560450 Bioactive AGN-PC-04TH1D
CFAMM00044124 CHEMBL160963 Bioactive SureCN5157539
CFAMM00044185 CHEMBL376700 Bioactive NESS 0327
CFAMM00044137 CHEMBL224609 Bioactive AGN-PC-00CNOX
CFAMM00044238 CHEMBL605108 Bioactive AGN-PC-07R6LQ
CFAMM00044028 CHEMBL287610 Bioactive SureCN7134813
CFAMM00044154 CHEMBL1788112 Bioactive [3H]RIMONABANT
CFAMM00044047 CHEMBL596163 Bioactive AGN-PC-07R5TV
CFAMM00044147 CHEMBL550982 Bioactive SureCN14155489
CFAMM00044106 DNC005420 Investigative Drug SR-147778
CFAMM00044024 DNC006099 Investigative Drug RIMONABANT HYDROCHLORIDE
CFAMM00044042 DNC009072 Investigative Drug AM-281
CFAMM00044135 DNC000189 Investigative Drug AM251

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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