CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name D(2) dopamine receptor Ligand Loxapine Family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00044565 Functional Category Approved Drug with Human Metabolite
Superfamily D(2) dopamine receptor Ligand Loxapine Superfamily
Class Class 217

Cousin Family NamesSeedsMembers
C-C chemokine receptor type 1 Ligand BX-471 Family 10 67
Progesterone receptor ligand CHEMBL253735 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00044557 DAP001149 Approved Drug Amoxapine
CFAMM00044565 DAP000311 Approved Drug Loxapine
CFAMM00044571 CHEMBL1201155 Bioactive Loxapine succinate
CFAMM00044561 CHEMBL213912 Bioactive AGN-PC-00HD58
CFAMM00044569 DNC011498 Investigative Drug ISOLOXAPINE

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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